Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RELA (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5970 Official gene symbol RELA Full name v-rel reticuloendotheliosis viral oncogene homolog A (avian) Aliases ,MGC131774,NFKB3,p65, Gene summary NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM] Location Chromosome: 11   Locus: 11q13 Gene position 65430443 - 65421067  Map Viewer Gene orientation minus Gene size 9377 bp Gene sequence >RELA:complement(10726862..10736238):Length=9377 AGCGCGCAGGCGCGGCCGGATTCCGGGCAGTGACGCGACGGCGGGCCGCGCGGCGCATTT CCGCCTCTGGCGAATGGCTCGTCTGTAGTGCACGCCGCGGGCCCAGCTGCGACCCCGGCC CCGCCCCCGGGACCCCGGCCATGGACGGTGAGGTCGCCCTCTGACCCCGCGGGGTGGCAT CGCCGGGGCCGCCGCGGCTGTGGCGGGAGCCCCCGCGCCGCTTTCCGCCCCTTCCTGCGC CGACGGGCGCTGCGCAGGGAGCGGTCGGCCTGCCGGATGGTGGCGCGGGGCGGGGCAGGC GGGGAGGGGTCTGACTCAGTTTCCCCTCTGGGTGGAGGGGGTGGCCCTTGACTCAGCATC CTCCCTGGGTGGGGGAGCAGAGGGAACCTTGACTCAGTTTCCCTCCACACCGTCCATGGG GGCAGCTCTGGCTTCGTTTCCCTATTAGGGGAGAACGCATCTGATTCAGTTTCCTCTCTG GAGGGAGGTGGGGCGTGCCCTCCCTCAATTTTCCTTAAGAAAGTACAACAGGCCCTGATT CAGCTTCCCTCTGGAGAAGAAGGATTCCTTACCCCGTTTTCCCTCAAGAAGCAGGTGTTT CTGGTTCCTTTCCTCCACCCCTTAGTTTCACCGCAGGTTCTAGGGAGCAGGTCCTGACTC AGTTCCCCTGGGAGGGAGCCTGGCTTCTCCTCTCCGTGGAGAGCAGATTCCTCCTTGTGA GAATGGGCATTGGGTGTGTGCTGACCCTGATCTCCCTCCCCTTTCAGAACTGTTCCCCCT CATCTTCCCGGCAGGTAAGTGGCCCCCGCGGCGGTCGGGGAGGTGCTCCCTGGGGTAGGG CAGTGGGGGCAGCCGCCTAATGGGGCTGCGGTGTCCCCTGGCAGAGCCAGCCCAGGCCTC TGGCCCCTATGTGGAGATCATTGAGCAGCCCAAGCAGCGGGGCATGCGCTTCCGCTACAA GTGCGAGGGGCGCTCCGCGGGCAGCATCCCAGGCGAGAGGAGCACAGATACCACCAAGAC CCACCCCACCATCAAGGTCAGCACTGCGCCAGGGTGTGCGGGGAAGGGACTGTGGAACCC CAGCCCTCTGTGTTTGGGAGTCAGGTTTGGATGTCTGGGCCTCTGTACTTTGGACAGATC AATGGCTACACAGGACCAGGGACAGTGCGCATCTCCCTGGTCACCAAGGACCCTCCTCAC CGGCCTCACCCCCACGAGCTTGTAGGAAAGGACTGCCGGGATGGCTTCTATGAGGCTGAG CTCTGCCCGGACCGCTGCATCCACAGGTGAGGTCCCTGCAGGCTAGGAGGCCCAGCATGA GGGGACAGGAGGCGGGCTATGAAGTAGCCGCTACAGTGTTACTCCTTTCTGGACCCAGGG CAGAATTCCTCACTCCTTGCCCTGACTCAGCTCTGCAAGTAAACTGCCTTTGTCTTGAAA TTATCTATTTGTACGTTTACTCTAGCAGATGAGTTCCAGGGGATACGGATGGGTCCCTAA TCACTTCTGAATTCCTGACCCCTGTAGCTGGAAGGACAAGTCCCTCAGAGTCACGTCTCT TGTTTGAGGAAGAAAACCATTGAACCAGCACTCTCCCCTGGAGTTGACATTGCAGTTGAC AGAGACAGGCTGTAAAAAAATATACAGGCCGGGCATAGTGGCTCATGCTTATAATCCTAG CACTTCGGGAGGCCAAGGCAGGAAGATCTCTTGAGCCTAGGAATTCAAGACTAGCCAAGG CAACATAGTGAGACCCCATGTCTACAAAAAATAAGAAATTAGCTGGGTATGGTGGCATGC GCCTATAGTCCCAGGGAGGCTGAGGTGGGAGGATCGCCTGAGCCCAGGAGGTCACTGCTG CGGCAAGCTATGATTGCACCACTGCACTTGGGTGGCAGGGCGATACCTTGTCTTTTTTTT TTTTTTTTTTTTTTTAAGAAAGAGTCTTGCTCTGTCCCCAGACTGGAGTGCAGTGGCGCG ATCTCAGCTCACTGCAACCTCCACCTTCCGGGTTCATGCCATTCTCCTGCCTCAGCTTCC CGAATAGCTGGGACTACAGGTGCCTGCCACCACGCCTGGCTAATTTTTTGTATTTTTTAG TAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCAATCTCCTGACCTTGTGATCTG CCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGCTTGAGCCACCGCACCCGGCCCGAC ACTGTGTCTCTTAAAAATAAATAAATACACAGATAAATAAACAAGGTGCTGTCAGAGTAA CAGTTTCAGTCCTGAAAATAAAACGAGGTCATAGGATAGAAGGATAACCTGGGGTGGGGG AGTTAGGGGAGCTGGTGTGTGATGACTTTAGATTGGGAGGTCAGGGAAGGCCTCCCTCAG CTAAGACTTGAATGGTGAGAAGGAGGAGAGAAGTAGGAAAAGAACATTCCAAGCCGACCA AACAAGTGCAAAGGCCTTGAGGTGGGAATGAGTGTCCTGTGTTTAGAGAGTGGAAAAGGA GCCCCGGTGGCTGTAAGCAGGGAGCCCACAGGGAGGCTGGCAGGGGCAGGGGCACGGAGG TGCTTGTCAGCTGAGTGAAGGGACAGGGTTCGTTGCAGCACAGTAGGAAGCCACTGGAGA GGGTTAGGCATGGAGCGATGATCTAGGGGTGGGCAGAGTAGGAAGGAGCAGGCTGGGCAA GGCAGGAAGGTCTGGGCTCTGTGAGAGACAGTGGGACAGACGACTGGGGGCGCTCAGTTT CCAGAACCTGGGAATCCAGTGTGTGAAGAAGCGGGACCTGGAGCAGGCTATCAGTCAGCG CATCCAGACCAACAACAACCCCTTCCAAGGTGAGGGCAAACCTGCCTGCCACACCCGCAC CCTCTGTCACCCTCCCCAGCCCGCCTTTCCTGCATCTCCCTCACTGGCCAAGACACAGTA AAGCTGGAATCTTGGTGCCCATTCAGTACTCTCCCACTTTACCACTGGGAAACTGAGTCC CAGGAGGGGACATGACATTCAGGCCACAGTGGAGTCAGTGCTGGGTTCTGCCTCCTCTAG GACTTGTGTTTCACACACGCACCAGCGGCCCTCCCAGCGCAGAGCTCCCTGCCCCCACTG ATAGCACCTATATCCCCACTTCCCCTGCTCTCCTGATCGCCTGTTTTCTTGGCAGTTCCT ATAGAAGAGCAGCGTGGGGACTACGACCTGAATGCTGTGCGGCTCTGCTTCCAGGTGACA GTGCGGGACCCATCAGGCAGGCCCCTCCGCCTGCCGCCTGTCCTTTCTCATCCCATCTTT GACAATCGTGAGTAGCGAGGGAGACGCAGGAAGGGGAGAGGGTGGGCCTGAATAGGAGGA AGGGGGTTGGGGTGAGTGTGGCCTGCAAGAGGCGCTCTGGCTTCATTCAATCATCTTGCG TATTTGTCTACTCTTCTCTGCCCAGCTCTTTGTTGGCTGGGGAGAGAGGGCAAAGAAGAC CCAGAGCTGTCCTTGAGGTGTAGCTCTGGCCTGGCAGGAAGTCTAGCAGAGAGTCTGATG GGAGATGGGCATTTTCAGTATTGTGTGATGAGAAGGTGGTGTGCCCACAACTGCGATAAT GACTCTAGGAAATGAACTCCCAGGAACAAGATAGTGTTCGAGAATGATGATTCAGTGATG GAAGCCCACAGATGAATTGGGCTGACTGATCAGCTGCAGTCTTTAGTTAAGTAACCAGCA GGATGAATGGAAATAAAACGAATCTGGAGCCCCAAGGATGGGAAACCAGGATAAACTGGG GGTCAGGAGGGAAGGGCTCATTGCCAAGGTGGGTATGGACTGGCCTTAAAGATTGCTTTG GTCAGGTGGAGAAAGAGTGTGATCAGATTGGCACCCACTGGACTATAAGCTCCGGGAGAG CAGAGAGGTTTGGGTTTTGTGTGTGGTCGTATTCTTGCTTAGATCAGTGTTGAGTGCACA GTAGGCAAATACTTGTTGAATCGGTTGGGGTGAGGAGCTAATAAGAAGGTCTGACTTTGG CTACAAAGGTGTAGGTGGCAAGCTCTGGGCAACCTTGACTCTGGGCTGGGCAGGGAAGTT GCATCTCCTGCAGGCCACCCTGGGGACCTCTCGTGGCTCAGGTCATCCTCCCTTGTTTTC ACTGCCTCAGGTGCCCCCAACACTGCCGAGCTCAAGATCTGCCGAGTGAACCGAAACTCT GGCAGCTGCCTCGGTGGGGATGAGATCTTCCTACTGTGTGACAAGGTGCAGAAAGGTATA CATCAGGAGGCAGGGGTGGGCTCTTGGGAGCAAGGGGTGAAGCTGAGCAGAGAAGTGGAG TGTCAGGTAACTGGCTTTGGATACTTCCTCCTGTGCCTCGGGGGCCTCAGGTGGGCCGAA GGGTGATGTATCAGAAGACAAGCATCAGAAGTTGAGGGGGAGACCATGGAGGGTTAGACA CACTGACCCACACTGCCACCGCATCTCCTGCAGAGGACATTGAGGTGTATTTCACGGGAC CAGGCTGGGAGGCCCGAGGCTCCTTTTCGCAAGCTGATGTGCACCGACAAGTGGCCATTG TGTTCCGGACCCCTCCCTACGCAGACCCCAGCCTGCAGGCTCCTGTGCGTGTCTCCATGC AGCTGCGGCGGCCTTCCGACCGGGAGCTCAGTGAGCCCATGGAATTCCAGTACCTGCCAG ATACAGGTACACAGCTGGGGTGGCAGCATCAGGGCAGCTGGGCTCTGTGCCGTGAGAGAG AGGCCAAGACTGCATGTCTGGGGCTGTGGTTGAGGGCCAGAAGCTGGAGTCAGAGCTTGG GATCCAAGAAACTGGAATCCATTTCTTGCCTCATTTAATAATAATGATACCTCAGACATT GAGCTAGTACTACACATCTGCCCCTATTCCAGGCACTTCACTGGATTACCTGATTTTAAT CTCATGACCCTTTTGAAGTAGGAGATAGTGTCCAACTTGCCTGGGTTCACGTGGCTAGTA AGTAGCAGAGTCTAGCAGAGTCAGCGTTGGAACCCAGGCCATCTGGCTTCAGGATCCTTT TGCCACACTGGTTGTCTTGTCACTACCATACAGCCCAGCCACATTTTGGTCGAGGTTTGA GTGTCCACTTGGTACCAGGGCCTGTGCCAGGTATTGTGAATACAAAAAATGAGTAAGACA TGCTCCCTGCCCTTCAGAGTCTCAGTCACTTGAGGAAGACAAATGTGCAAAACAGATCCT TAAGTCACGGAATGACATGTGAAATGGAGGTGTGCGCAGAGAAGCACGGGGGCACAGTGG CCTCCGGGGAGCTGGAGACAGCTGCATGGAGAAGGTGGCATTGAAGCTGGAGAAAGACAC AGAAGTGTGTTCTCCAGGCAGGTGGCCCAGCACCTGGAAGGGAAGGGGTGTTGGCAACTG CACGGCCTATTCAGGGCCACCTTCGTGGTTTGAGCTGATGTTGGGCAGTGAGCAGGCTCA GAGATTGGAGGGCCTGGTTAAGCTGAAGGCCTCTAAGCAGAGAGGTGACAGGAGCAGATT TGGAAGTTGACTCAGGAGGCCACGTGTAGAAGATCAGAGACAGACAGACTCAAAGCAGGG AGGCCATTCTGGAAATGTTGCTGTAGTCCAGGAAGAGAAGATGCGGCACAAACCTTACAG AAGGAATAGCAGAGCAAGATCACATCTCCACCACTGTCCTCAGTTACCCTTCAGCCCTGC AGCCGTTTTGCGTCTTACAGACCAAGCTCAGTCTCACCTCAGGACCTGTGTCTAGCTGTT GCCTCTGCTTGGAATGCCCAAGGTTTTAATGCAAGTGGCTCATGCCAGTCCTTCCCTGAC CTCTAAATTAGCCCTTCCCTCTACATTTAGACTGTCCTGACCTCACTTCCAGTATTGTTA CATCACCATATCGTCCCTGGACCACCGTCACTTGAGATTTTCTGGTTTGGTTTTGTTTGT TTGTTTGAGACAGAGTCTCACTCTTGTCGCCCAGGCTGGAGTGCAGTGGTGCAATCTCGG CTCACTGCAACCTCCACCTCCCGGGTTCAAGTGATTCTCCCTGCCTCAGCCTCCCGAGTA GCTGGGACTACAGGCGCCCGCCACCACATCCGGCTAATTTTTTGTATTTTTAGTAGAGAC GGGGTTTTCACCATGTTGGCCAGGGTGGTCTCGATCTCTTGACCTCGTGATCCACCCGCC TCGACCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCTGGCCGAGATTTTCT GGTTTGTATATATGATTGTGTCCCTCTCACTTTTTCACTAGGATGCCAACTTTTTGGGAG CAGACACCTTGTGTGCATACTCACGGCCACATCCCCAGTGTCTAGAAGGGAGGCTGGCAC ATAGTAGGTGCTTGATAAATATATGTCAAGTTACTGGCGGGGAGTGAGAGAAAAGAAGAT AATCATTCCAAGGTTTCTAGCTTTGGTGACAGGGCAGATGGCGGATGGTCAGGGAATGCA GGAGAAAGAACCTAGTTTTTGAGGGATGATGAGGTTGTCTTTGAATTGATGGAATTGAAG TGCTTTGGAGCTACTGAAATACCACTGTAATTAGAAAGACAGTTCTGAAAGCTCTGACTA AAATATGAAACCATTAGAGATAAGAATAAGAGTCTCTGCTGAAGTCTTAAGGCAGTTGTG CCTCAGCTGCCCCAGAGTGCCAAGAAATTCTCGCCAGGCCTGGGTGGAGGCTGACAATGA GCCAGGATGTGAGCAGTGCAGGAAGGTGTGAGCTGGAGGCTGGGGCCCCCCAGGTCTCCT CTTTGCCCAGAGCATGGCCCCTGTACTCGGCCTCACCATGTGGTCTTAGAGGGGCAGATT CAGCCAACAGAGGCCTCCAAAAGCTGTGGGATTCTCAGAACTGCTGAGTGTCACACATCC CTTCTCATTGGCAGAGAAGGTTGGGAGAATGGGTCTTGGGAAAGCCTGGCTCCTCCCCTT CCTCCTGAGGGACCTTTGAGAGCGTCGGGGACCCACCTGAGGAGAGCAAGTCCCACTTCT CCCCCTTACTTTCCCAGACGATCGTCACCGGATTGAGGAGAAACGTAAAAGGACATATGA GACCTTCAAGAGCATCATGAAGAAGAGTCCTTTCAGCGGTGAGATGGGGACTGGGAAAGC CAGAGAGGAAGGCAGCGGGCAGGGAGGGGACACCCTGGGGCTGAGAACTGACCTAGCCCT TGCCCTACAGGACCCACCGACCCCCGGCCTCCACCTCGACGCATTGCTGTGCCTTCCCGC AGCTCAGCTTCTGTCCCCAAGCCAGGTAAGGATTTCCTTTTGTCCCACTGGAACGACAGG TTCAGCTCTGTTCAGCTGAGGAGCAGTGGAGATGAAGACTCCTGGGCCCCATTACAGACC TACTGAATCAGAGGCTTTGAAAGGATGGCGCAGGAACCAGCGACTTCCTGGGATGCTAAT GCACACTGAAGCCTGGGAACCACCGTGCCACTTAAATTCTATATTGGGTATCTTGGGAAT CAGAAGTTAAAAATGCAGAATCTCTGCTCTCATCTCTCACTTGAATTGGGGGAACAAAAA TCACCTCTAAATTAGCAAGATGTGTGTGCCTGTGCGAGGCTCAAAAACTGACAAGCTCTG CACTTCAGGCCGCTGCTCACTTGGTGCTCCATGGGCTCATTGCCTCTCAGGACTTAGTTT TTCAGCTGTAAACTGAGGAGTCCAGCTTATCTCTCCAAGTGTCCCTTCCTCTAAAAGGCT GGAAGAGTTTCGTGGGCTTGAGTAGTCAGGGAGGACTCCAAGGTGGAGGTGTGGCTAGAA CTGGACCCTACAGGCTGGGTCAGATGGGGTAAGAGGAAGGAGATAGGGTGTTGGCAGTGA CTCCCTAGAGAGGGATTGAGCCTGAGCACCATGAAGAGGGGCTGGGGTACAGAGGACGGG GTGGATCTCTAGGGCTTTCTCTGACCCCTGCCTCTCTGTCTCTCTCCTCCAGCACCCCAG CCCTATCCCTTTACGTCATCCCTGAGCACCATCAACTATGATGAGTTTCCCACCATGGTG TTTCCTTCTGGGCAGATCAGCCAGGCCTCGGCCTTGGCCCCGGCCCCTCCCCAAGTCCTG CCCCAGGCTCCAGCCCCTGCCCCTGCTCCAGCCATGGTATCAGCTCTGGCCCAGGCCCCA GCCCCTGTCCCAGTCCTAGCCCCAGGCCCTCCTCAGGCTGTGGCCCCACCTGCCCCCAAG CCCACCCAGGCTGGGGAAGGAACGCTGTCAGAGGCCCTGCTGCAGCTGCAGTTTGATGAT GAAGACCTGGGGGCCTTGCTTGGCAACAGCACAGACCCAGCTGTGTTCACAGACCTGGCA TCCGTCGACAACTCCGAGTTTCAGCAGCTGCTGAACCAGGGCATACCTGTGGCCCCCCAC ACAACTGAGCCCATGCTGATGGAGTACCCTGAGGCTATAACTCGCCTAGTGACAGGGGCC CAGAGGCCCCCCGACCCAGCTCCTGCTCCACTGGGGGCCCCGGGGCTCCCCAATGGCCTC CTTTCAGGAGATGAAGACTTCTCCTCCATTGCGGACATGGACTTCTCAGCCCTGCTGAGT CAGATCAGCTCCTAAGGGGGTGACGCCTGCCCTCCCCAGAGCACTGGGTTGCAGGGGATT GAAGCCCTCCAAAAGCACTTACGGATTCTGGTGGGGTGTGTTCCAACTGCCCCCAACTTT GTGGATGTCTTCCTTGGAGGGGGGAGCCATATTTTATTCTTTTATTGTCAGTATCTGTAT CTCTCTCTCTTTTTGGAGGTGCTTAAGCAGAAGCATTAACTTCTCTGGAAAGGGGGGAGC TGGGGAAACTCAAACTTTTCCCCTGTCCTGATGGTCAGCTCCCTTCTCTGTAGGGAACTC TGGGGTCCCCCATCCCCATCCTCCAGCTTCTGGTACTCTCCTAGAGACAGAAGCAGGCTG GAGGTAAGGCCTTTGAGCCCACAAAGCCTTATCAAGTGTCTTCCATCATGGATTCATTAC AGCTTAATCAAAATAACGCCCCAGATACCAGCCCCTGTATGGCACTGGCATTGTCCCTGT GCCTAACACCAGCGTTTGAGGGGCTGGCCTTCCTGCCCTACAGAGGTCTCTGCCGGCTCT TTCCTTGCTCAACCATGGCTGAAGGAAACCAGTGCAACAGCACTGGCTCTCTCCAGGATC CAGAAGGGGTTTGGTCTGGGACTTCCTTGCTCTCCCTCTTCTCAAGTGCCTTAATAGTAG GGTAAGTTGTTAAGAGTGGGGGAGAGCAGGCTGGCAGCTCTCCAGTCAGGAGGCATAGTT TTTACTGAACAATCAAAGCACTTGGACTCTTGCTCTTTCTACTCTGAACTAATAAATCTG TTGCCAAGCTGGCTAGA OMIM ID 164014