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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RELA (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001889 liver development IEA GO:0001942 hair follicle development IEA GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0006117 acetaldehyde metabolic process IEA GO:0006351 transcription, DNA-dependent IDA GO:0006916 anti-apoptosis IDA GO:0006916 anti-apoptosis TAS GO:0006952 defense response IEA GO:0006954 inflammatory response IDA GO:0006968 cellular defense response NAS GO:0007568 aging IEA GO:0008063 Toll signaling pathway TAS GO:0008284 positive regulation of cell proliferation IEA GO:0009612 response to mechanical stimulus IEA GO:0009617 response to bacterium IEA GO:0009887 organ morphogenesis IEA GO:0010033 response to organic substance IDA GO:0010035 response to inorganic substance IEA GO:0010224 response to UV-B IDA GO:0014040 positive regulation of Schwann cell differentiation IEA GO:0014070 response to organic cyclic compound IEA GO:0019221 cytokine-mediated signaling pathway IDA GO:0031293 membrane protein intracellular domain proteolysis TAS GO:0032332 positive regulation of chondrocyte differentiation IEA GO:0032495 response to muramyl dipeptide IEA GO:0032570 response to progesterone stimulus IEA GO:0032868 response to insulin stimulus IEA GO:0033590 response to cobalamin IEA GO:0034097 response to cytokine stimulus IEA GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0042177 negative regulation of protein catabolic process IEA GO:0042493 response to drug IEA GO:0042542 response to hydrogen peroxide IEA GO:0043066 negative regulation of apoptosis IMP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEP GO:0043200 response to amino acid stimulus IEA GO:0043278 response to morphine IEA GO:0044419 interspecies interaction between organisms IEA GO:0045084 positive regulation of interleukin-12 biosynthetic process IEA GO:0045087 innate immune response TAS GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IMP GO:0046627 negative regulation of insulin receptor signaling pathway IEA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0050727 regulation of inflammatory response IEA GO:0050727 regulation of inflammatory response ISS GO:0050852 T cell receptor signaling pathway TAS GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS GO:0051591 response to cAMP IEA GO:0051607 defense response to virus NAS GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway IDA GO:0070555 response to interleukin-1 IGI GO:0071222 cellular response to lipopolysaccharide IEA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005667 transcription factor complex IDA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol IEA GO:0005829 cytosol TAS GO:0043234 protein complex IEA molecular_function GO:0003677 DNA binding IDA GO:0003682 chromatin binding IDA GO:0003682 chromatin binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003705 sequence-specific distal enhancer binding RNA polymerase II transcription factor activity IDA GO:0003705 sequence-specific distal enhancer binding RNA polymerase II transcription factor activity IEA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IEA GO:0008134 transcription factor binding IPI GO:0019901 protein kinase binding IEA GO:0019901 protein kinase binding IPI GO:0031625 ubiquitin protein ligase binding IPI GO:0033613 activating transcription factor binding IPI GO:0042301 phosphate ion binding IDA GO:0042802 identical protein binding IDA GO:0042802 identical protein binding IPI GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IDA GO:0047485 protein N-terminus binding IPI GO:0051059 NF-kappaB binding IPI GO:0070491 repressing transcription factor binding IPI GO:0071532 ankyrin repeat binding IEA

Protein-protein interaction details for RELA (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FOS Two-hybrid physical 10488148 PIAS3 Two-hybrid physical 15140884 RNF25 Two-hybrid physical 12748188 PPP1R13L Two-hybrid physical 10336463 ING4 Two-hybrid physical 15029197 MAP3K8 Affinity Capture-MS physical 14743216 REL Affinity Capture-MS physical 14743216 NFKB1 Affinity Capture-MS physical 14743216 NFKB2 Affinity Capture-MS physical 14743216 IQGAP2 Affinity Capture-MS physical 14743216 AKAP8L Affinity Capture-MS physical 14743216 RELB Affinity Capture-MS physical 14743216 NCOA6 Reconstituted Complex physical 10847592 BARD1 Affinity Capture-Western physical 12700228 BRCA1 Reconstituted Complex physical 12700228 BRCA1 Affinity Capture-Western physical 12700228 DHX9 Affinity Capture-Western physical 15355351 DHX9 Reconstituted Complex physical 15355351 TNIP2 Affinity Capture-MS physical 14743216 TBK1 Affinity Capture-MS physical 14743216 PIAS3 Reconstituted Complex physical 15140884 PIAS3 Affinity Capture-Western physical 15140884 PIAS3 Affinity Capture-Western physical 15140884 CREBBP Affinity Capture-Western physical 15140884 ING4 Affinity Capture-Western physical 15029197 UNC5CL Affinity Capture-Western physical 14769797 RNF25 Reconstituted Complex physical 12748188 RNF25 Reconstituted Complex physical 12748188 RNF25 Affinity Capture-Western physical 12748188 TRIB3 Affinity Capture-Western physical 12736262 TRIB3 Affinity Capture-Western physical 12736262 CEBPB Affinity Capture-Western physical 12707271 BRCA1 Reconstituted Complex physical 12700228 HMGA2 Reconstituted Complex physical 12693954 NFKBIB Affinity Capture-Western physical 12672800 NFKBIB Reconstituted Complex physical 12672800 HMGB1 Affinity Capture-Western physical 12665595 NCOR2 Two-hybrid physical 12589049 NCOR2 Affinity Capture-Western physical 12589049 HDAC3 Affinity Capture-Western physical 11533489 HDAC3 Affinity Capture-Western physical 11533489 NFKBIA Reconstituted Complex physical 11533489 EP300 Biochemical Activity physical 12419806 HDAC1 Affinity Capture-Western physical 12419806 HDAC2 Affinity Capture-Western physical 12419806 NFKBIA Reconstituted Complex physical 12419806 NFKBIA Reconstituted Complex physical 12419806 NCF1 Reconstituted Complex physical 12618429 NCF1 Affinity Capture-Western physical 12618429 HDAC1 Affinity Capture-Western physical 11931769 HDAC1 Affinity Capture-Western physical 11931769 HDAC1 Reconstituted Complex physical 11931769 HDAC1 Reconstituted Complex physical 11931769 CREBBP Reconstituted Complex physical 11931769 CREBBP Affinity Capture-Western physical 11931769 HDAC1 Affinity Capture-Western physical 11564889 HDAC1 Reconstituted Complex physical 11564889 CSNK2A1 Affinity Capture-Western physical 10938077 CSNK2A2 Affinity Capture-Western physical 10938077 CSNK2A1 Biochemical Activity physical 10938077 CSNK2A2 Biochemical Activity physical 10938077 CREBBP Reconstituted Complex physical 9548485 CREBBP Two-hybrid physical 9548485 CREBBP Phenotypic Enhancement genetic 9548485 CREBBP Phenotypic Suppression genetic 9482849 CREBBP Phenotypic Enhancement genetic 9096323 CREBBP Two-hybrid physical 9096323 EP300 Two-hybrid physical 9096323 CREBBP Affinity Capture-Western physical 9096323 EP300 Affinity Capture-Western physical 9096323 EP300 Phenotypic Enhancement genetic 9096323 CREBBP Reconstituted Complex physical 9096323 EP300 Reconstituted Complex physical 9096323 HEXIM1 Reconstituted Complex physical 12581153 NFKB1 Reconstituted Complex physical 8798655 JUN Two-hybrid physical 10488148 FOS Phenotypic Enhancement genetic 10488148 JUN Phenotypic Enhancement genetic 10488148 MEN1 Reconstituted Complex physical 11526476 MEN1 Affinity Capture-Western physical 11526476 PPP2CA Reconstituted Complex physical 11591705 PPP2CB Reconstituted Complex physical 11591705 CDK9 Reconstituted Complex physical 12173051 CDK9 Affinity Capture-Western physical 12173051 PML Affinity Capture-Western physical 12540841 NOTCH1 Affinity Capture-Western physical 8642313 ETHE1 Affinity Capture-Western physical 12398897 ETHE1 Reconstituted Complex physical 12398897 AHR Affinity Capture-Western physical 11114727 SRF Reconstituted Complex physical 8670842 PPARA Reconstituted Complex physical 10542237 ITGB3BP Affinity Capture-Western physical 12244126 TERT Affinity Capture-Western physical 12517770 APBA2 Two-hybrid physical 10777610 APBA2 Affinity Capture-Western physical 10777610 APBA2 Affinity Capture-Western physical 10777610 RFC1 Affinity Capture-Western physical 12509469 RFC1 Reconstituted Complex physical 12509469 RFC1 Affinity Capture-Western physical 12509469 SP1 Affinity Capture-Western physical 12055073 NFKBIA Affinity Capture-Western physical 9990853 BTRC Affinity Capture-Western physical 9990853 NFKBIA Affinity Capture-Western physical 9990853 BTRC Affinity Capture-Western physical 9990853 RXRA Reconstituted Complex physical 10075655 SP1 Reconstituted Complex physical 7933095 SP1 Reconstituted Complex physical 7933095 PGR Reconstituted Complex physical 8626413 PPP1R13L Reconstituted Complex physical 12134007 NFKBIE Two-hybrid physical 9315679 NFKBIE Reconstituted Complex physical 9315679 NFKBIE Affinity Capture-Western physical 9315679 NR3C1 Affinity Capture-Western physical 8290595 NFKBIA Affinity Capture-Western physical 11313474 AES Two-hybrid physical 10660609 AES Reconstituted Complex physical 10660609 AES Affinity Capture-Western physical 10660609 TLE1 Affinity Capture-Western physical 10660609 NFKBIB Affinity Capture-Western physical 8816457 NFKBIB Reconstituted Complex physical 8816457 REL Reconstituted Complex physical 8139561 NFKBIA Affinity Capture-Western physical 8139561 REL Affinity Capture-Western physical 8139561 AHR Affinity Capture-Western physical 12181450 NFKBIA Reconstituted Complex physical 9738011 NKRF Reconstituted Complex physical 10562553 ASCC1 Reconstituted Complex physical 12077347 ASCC2 Reconstituted Complex physical 12077347 ASCC3 Reconstituted Complex physical 12077347 ASCC1 Two-hybrid physical 12077347 ASCC2 Two-hybrid physical 12077347 ASCC3 Two-hybrid physical 12077347 NCOR2 Two-hybrid physical 10777532 NCOR2 Two-hybrid physical 10777532 NCOR2 Reconstituted Complex physical 10777532 NCOR2 Reconstituted Complex physical 10777532 PPP4C Reconstituted Complex physical 9837938 PARP1 Affinity Capture-Western physical 11590148 PARP1 Reconstituted Complex physical 11590148 MTPN Reconstituted Complex physical 11971907 MTPN Affinity Capture-Western physical 11971907 NFKB2 Reconstituted Complex physical 8413211 NFKB2 Affinity Capture-Western physical 8413211 PRKCZ Biochemical Activity physical 11684013 PRKCZ Affinity Capture-Western physical 11684013 POU2F1 Reconstituted Complex physical 12019209 POU2F1 Affinity Capture-Western physical 12019209 TAF1 Reconstituted Complex physical 9584164 TBP Reconstituted Complex physical 9584164 TAF6 Reconstituted Complex physical 9584164 TAF11 Reconstituted Complex physical 9584164 TWIST1 Affinity Capture-Western physical 12553906 MYC Affinity Capture-Western physical 12027803 TBP Reconstituted Complex physical 7706261 GTF2B Reconstituted Complex physical 7706261 TBP Phenotypic Enhancement genetic 7706261 KPNA2 Reconstituted Complex physical 12504098 REL Reconstituted Complex physical 11967310 REL Two-hybrid physical 11967310 NKX2-1 Affinity Capture-Western physical 12040027 PPP1R13L Reconstituted Complex physical 10336463 RELA Two-hybrid physical 10336463 PPP1R13L Affinity Capture-Western physical 10336463 TAF4B Reconstituted Complex physical 9724652 TAF4B Reconstituted Complex physical 9724652 HDAC2 Affinity Capture-Western physical 12138131 HDAC2 Reconstituted Complex physical 12138131 STAT3 Affinity Capture-Western physical 12057007 STAT3 Reconstituted Complex physical 12057007 EGR1 Reconstituted Complex physical 10671503 NFKBIA Reconstituted Complex physical 9751059 CEBPB Reconstituted Complex physical 9570146 CEBPD Reconstituted Complex physical 9570146 FUS Affinity Capture-Western physical 11278855 FUS Reconstituted Complex physical 11278855 NR3C1 Reconstituted Complex physical 10995388 NR3C1 Reconstituted Complex physical 7659084 IRF8 Reconstituted Complex physical 8550813 IRF2 Reconstituted Complex physical 8550813 IRF9 Reconstituted Complex physical 8550813 DHX9 Two-hybrid physical 15355351 TBP Affinity Capture-Western physical 10839990 ETHE1 Affinity Capture-Western physical 17353187 ING4 Affinity Capture-Western physical 18779315 ING4 Reconstituted Complex physical 18779315 PDLIM2 Affinity Capture-Western physical 17468759 UBC Reconstituted Complex physical 17468759 UBC Affinity Capture-Western physical 17183367 UBC Affinity Capture-Western physical 17183367 COMMD1 Biochemical Activity physical 17183367 SOCS1 Reconstituted Complex physical 17183367 SOCS1 Reconstituted Complex physical 17183367 KDM2A Affinity Capture-Western physical 20080798 NSD1 Affinity Capture-Western physical 20080798 KDM2A Biochemical Activity physical 20080798 SETD7 Biochemical Activity physical 19262565 SETD7 Affinity Capture-Western physical 19262565 SETD7 Reconstituted Complex physical 19262565 NFKBIA Affinity Capture-Western physical 19219072 SIRT5 Affinity Capture-Western physical 19135889 SIRT6 Affinity Capture-Western physical 19135889 SIRT6 Reconstituted Complex physical 19135889 SIRT6 Reconstituted Complex physical 19135889 USP31 Affinity Capture-Western physical 16214042 HDAC1 Affinity Capture-Western physical 20001970 HDAC1 Affinity Capture-Western physical 20001970 USF2 Two-hybrid physical 20936779 SETD7 Biochemical Activity physical 19864627 ATF4 Affinity Capture-Western physical 19648113 BANP Affinity Capture-Western physical 18981184 SIRT1 Affinity Capture-Western physical 17041012 BRMS1 Affinity Capture-Western physical 17000776 BRMS1 Affinity Capture-Western physical 17000776 BRMS1 Reconstituted Complex physical 17000776 HDAC1 Affinity Capture-Western physical 17000776 C11orf17 Affinity Capture-Western physical 16998474 NFKB1 Affinity Capture-Western physical 16740634 SETD7 Affinity Capture-Western physical 18650421 ESR1 Affinity Capture-Western physical 16497877 CARM1 Affinity Capture-Western physical 16497732 HDAC1 Affinity Capture-Western physical 16483679 NCOR2 Reconstituted Complex physical 16382138 CHUK Biochemical Activity physical 16382138 NFKB1 Co-localization physical 16319923 NFKB1 Co-localization physical 16319923 ATF3 Reconstituted Complex physical 16291753 ATF3 Affinity Capture-Western physical 16291753 PARP1 Reconstituted Complex physical 16204234 PARP1 Reconstituted Complex physical 16204234 NFKB1 Reconstituted Complex physical 16204234 NFKB1 Reconstituted Complex physical 16204234 EP300 Affinity Capture-Western physical 12403783 NFKBIA Affinity Capture-Western physical 16105840 NFKB1 Affinity Capture-Western physical 16105840 NFKBIA Affinity Capture-Western physical 7878004 CARM1 Affinity Capture-Western physical 15616592 CARM1 Reconstituted Complex physical 15616592 MYC Affinity Capture-Western physical 15616592 EP300 Reconstituted Complex physical 11585920 NFKBIA Affinity Capture-Western physical 20980497 NFKB1 Affinity Capture-Western physical 20237821 EP300 Affinity Capture-Western physical 11567019 SNIP1 Reconstituted Complex physical 11567019 PARP1 Affinity Capture-Western physical 18280497 EP300 Affinity Capture-Western physical 18280497 CARM1 Affinity Capture-Western physical 18280497 PRMT1 Affinity Capture-Western physical 18280497 PRMT1 Affinity Capture-Western physical 18280497 RELA Affinity Capture-Western physical 18280497 EP300 Affinity Capture-Western physical 18280497 PARP1 Affinity Capture-Western physical 18280497 CARM1 Affinity Capture-Western physical 18280497 PRMT1 Reconstituted Complex physical 18280497 HDAC2 Affinity Capture-Western physical 11395507 SP1 Affinity Capture-Western physical 18249093 SP1 Affinity Capture-Western physical 18249093 CREBBP Affinity Capture-Western physical 18241676 MAFK Affinity Capture-Western physical 18241676 CHUK Biochemical Activity physical 15489227 IKBKB Biochemical Activity physical 15489227 TBK1 Biochemical Activity physical 15489227 IKBKE Biochemical Activity physical 15489227 TAF9 Reconstituted Complex physical 15489227 AES Reconstituted Complex physical 15489227 HDAC2 Affinity Capture-Western physical 10958685 CREBBP Affinity Capture-Western physical 10542243 EP300 Affinity Capture-Western physical 15192014 HDAC1 Affinity Capture-Western physical 15192014 HDAC3 Affinity Capture-Western physical 15192014 HDAC1 Affinity Capture-Western physical 15192014 HDAC3 Affinity Capture-Western physical 15192014 RPS3 Affinity Capture-Western physical 18045535 RPS3 Affinity Capture-Western physical 18045535 EP300 Reconstituted Complex physical 10235267 CREBBP Reconstituted Complex physical 10235267 MED15 Reconstituted Complex physical 10235267 MED23 Reconstituted Complex physical 10235267 MED7 Reconstituted Complex physical 10235267 PPARD Affinity Capture-Western physical 18037904 CREBBP Reconstituted Complex physical 9659924 PSMD10 Affinity Capture-Western physical 17904523 PSMD10 Affinity Capture-Western physical 17904523 PSMD10 Reconstituted Complex physical 17904523 PSMD10 Reconstituted Complex physical 17904523 ESR1 Affinity Capture-Western physical 17932106 ESR1 Reconstituted Complex physical 17932106 HDAC1 Affinity Capture-Western physical 17827154 HDAC2 Affinity Capture-Western physical 17827154 NFKBIA Affinity Capture-Western physical 11231305 DPF2 Reconstituted Complex physical 20460684 CREBBP Affinity Capture-Western physical 17362989 HDAC2 Affinity Capture-Western physical 20388487 NFKBIA Affinity Capture-Western physical 8887633 NFKBIA Reconstituted Complex physical 8887633 NFKBIA Affinity Capture-Western physical 8978697 NFKBIA Affinity Capture-Western physical 7628694 NFKBIA Affinity Capture-Western physical 11287411 NFKBIA Affinity Capture-Western physical 20065107 HDAC2 Affinity Capture-Western physical 20065107 SP1 Affinity Capture-Western physical 20861353 COMMD1 Affinity Capture-Western physical 19270718 CUL2 Affinity Capture-Western physical 19270718 PLK1 Reconstituted Complex physical 21610149 UBC Affinity Capture-Western physical 20048074 UBC Affinity Capture-Western physical 20048074 COMMD1 Affinity Capture-Western physical 20048074 NFKBIA Affinity Capture-Western physical 20551178 NFKBIA Affinity Capture-Western physical 20551178 NFKBIA Affinity Capture-Western physical 10066434 NFKB1 Reconstituted Complex physical 2050119 KAT2A Affinity Capture-Western physical 19339690 COMMD1 Affinity Capture-Western physical 19339690 UBC Affinity Capture-Western physical 19339690 UBC Reconstituted Complex physical 19339690 KAT2A Affinity Capture-Western physical 19339690 KAT2A Reconstituted Complex physical 19339690 AFF1 Affinity Capture-MS physical 21030982 AFF1 Affinity Capture-Western physical 21030982 UBC Affinity Capture-Western physical 19064727 KEAP1 Two-hybrid physical 21262351 KEAP1 Affinity Capture-Western physical 21262351 KEAP1 Affinity Capture-Western physical 21262351 KEAP1 Reconstituted Complex physical 21262351 TP63 Affinity Capture-Western physical 22020940 TP63 Affinity Capture-Western physical 22020940 UBC Affinity Capture-Western physical 22020940 UBC Affinity Capture-Western physical 19330832 NFKBIA Affinity Capture-Western physical 20797629 AATF Affinity Capture-Western physical 17157788 NFKBIA Affinity Capture-Western physical 22022389 CHUK Affinity Capture-MS physical 21903422 RPL13 Two-hybrid physical 21900206 MAPK14 Two-hybrid physical 21900206 NFKBIB Affinity Capture-Western physical 22081069 NFKBIA Affinity Capture-Western physical 22081069 NFKBIA Affinity Capture-Western physical 22081069 NFKBIB Affinity Capture-Western physical 22081069 NFKBIA Biochemical Activity physical 22081069 SOCS1 Affinity Capture-Western physical 21084693 SOCS1 Affinity Capture-Western physical 21084693 UBC Affinity Capture-Western physical 21084693 UBC Affinity Capture-Western physical 21084693