Entrez gene ID | | 5978 |
Official gene symbol | | REST |
Full name | | RE1-silencing transcription factor |
Aliases | | ,NRSF,XBR, |
Gene summary | | This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q12 |
Gene position | | 57774042 - 57802010 Map Viewer |
Gene orientation | | plus |
Gene size | | 27969 bp |
Gene sequence |
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OMIM ID | | 600571 |