Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for REST (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5978
Official gene symbolREST
Full nameRE1-silencing transcription factor
Aliases,NRSF,XBR,
Gene summaryThis gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described [provided by RefSeq]
LocationChromosome: 4   Locus: 4q12
Gene position57774042 - 57802010  Map Viewer
Gene orientationplus
Gene size27969 bp
Gene sequence
OMIM ID600571