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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CCL2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6347 Official gene symbol CCL2 Full name chemokine (C-C motif) ligand 2 Aliases ,GDCF-2,HC11,HSMCR30,MCAF,MCP-1,MCP1,MGC9434,SCYA2,SMC-CF, Gene summary This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq] Location Chromosome: 17   Locus: 17q11.2-q12 Gene position 32582296 - 32584222  Map Viewer Gene orientation plus Gene size 1927 bp Gene sequence >CCL2:7319290..7321216:Length=1927 GAGGAACCGAGAGGCTGAGACTAACCCAGAAACATCCAATTCTCAAACTGAAGCTCGCAC TCTCGCCTCCAGCATGAAAGTCTCTGCCGCCCTTCTGTGCCTGCTGCTCATAGCAGCCAC CTTCATTCCCCAAGGGCTCGCTCAGCCAGGTAAGGCCCCCTCTTCTTCTCCTTGAACCAC ATTGTCTTCTCTCTGAGTTATCATGGACCATCCAAGCAGACGTGGTACCCACAGTCTTGC TTTAACGCTACTTTTCCAAGATAAGGTGACTCAGAAAAGGACAAGGGGTGAGCCCAACCA CACAGCTGCTGCTCGGCAGAGCCTGAACTAGAATTCCAGCTGTGAACCCCAAATCCAGCT CCTTCCAGGATTCCAGCTCTGGGAACACACTCAGCGCAGTTACTCCCCCAGCTGCTTCCA GCAGAGTTTGGGGATCAGGGTAATCAAAGAGAGGGTGGGTGTGTAGGCTGTTTCCAGACA CGCTGGAGACCCAGAATCTGGTCTGTGCTTCATTCACCTTAGCTTCCAGAGACGGTGACT CTGCAGAGGTAATGAGTATCAGGGAAACTCATGACCAGGCATAGCCTATTCAGAGTCTAA AAGGAGGCTCATAGTGGGGCTCCCCAGCTGATCTTCCCTGGTGCTGATCATCTGGATTAT TGGTCCGTCTTAATGACACTTGTAGGCATTATCTAGCTTTAACAGCTCCTCCTTCTCTCT GTCCATTATCAATGTTATATACCCATTTTACAGCATAGGAAACTGAGTCATTGGGTCAAA GATCACATTCTAGCTCTGAGGTATAGGCAGAAGCACTGGGATTTAATGAGCTCTTTGTCT TCTCCTGCCTGCCTTTTGCTTTTTCCTCATGACTCTTTTCTGCTCTTAAGATCAGAATAA TCCAGTTCATCCTAAAATGCTTTTTCTTTGTGGTTTATTTTCCAGATGCAATCAATGCCC CAGTCACCTGCTGTTATAACTTCACCAATAGGAAGATCTCAGTGCAGAGGCTCGCGAGCT ATAGAAGAATCACCAGCAGCAAGTGTCCCAAAGAAGCTGTGATGTGAGTTCAGCACACCA ACCTTCCCTGGCCTGAAGTTCTTCCTTGTGGAGCAAGGGACAAGCCTCATAAACCTAGAG TCAGAGAGTGCACTATTTAACTTAATGTACAAAGGTTCCCAATGGGAAAACTGAGGCACC AAGGGAAAAAGTGAACCCCAACATCACTCTCCACCTGGGTGCCTATTCAGAACACCCCAA TTTCTTTAGCTTGAAGTCAGGATGGCTCCACCTGGACACCTATAGGAGCAGTTTGCCCTG GGTTCCCTCCTTCCACCTGCGTTCCTCCTCTAGCTCCCATGGCAGCCCTTTGGTGCAGAA TGGGCTGCACTTCTAGACCAAAACTGCAAAGGAACTTCATCTAACTCTGTCCTCCCTCCC CACAGCTTCAAGACCATTGTGGCCAAGGAGATCTGTGCTGACCCCAAGCAGAAGTGGGTT CAGGATTCCATGGACCACCTGGACAAGCAAACCCAAACTCCGAAGACTTGAACACTCACT CCACAACCCAAGAATCTGCAGCTAACTTATTTTCCCCTAGCTTTCCCCAGACACCCTGTT TTATTTTATTATAATGAATTTTGTTTGTTGATGTGAAACATTATGCCTTAAGTAATGTTA ATTCTTATTTAAGTTATTGATGTTTTAAGTTTATCTTTCATGGTACTAGTGTTTTTTAGA TACAGAGACTTGGGGAAATTGCTTTTCCTCTTGAACCACAGTTCTACCCCTGGGATGTTT TGAGGGTCTTTGCAAGAATCATTAATACAAAGAATTTTTTTTAACATTCCAATGCATTGC TAAAATATTATTGTGGAAATGAATATTTTGTAACTATTACACCAAATAAATATATTTTTG TACAAAA OMIM ID 158105