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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CCL2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001525 angiogenesis TAS GO:0001666 response to hypoxia IEA GO:0001938 positive regulation of endothelial cell proliferation IEA GO:0002548 monocyte chemotaxis IDA GO:0006468 protein phosphorylation TAS GO:0006874 cellular calcium ion homeostasis IEA GO:0006916 anti-apoptosis IDA GO:0006935 chemotaxis IEA GO:0006954 inflammatory response IEA GO:0006959 humoral immune response TAS GO:0007155 cell adhesion TAS GO:0007165 signal transduction NAS GO:0007166 cell surface receptor linked signaling pathway TAS GO:0007179 transforming growth factor beta receptor signaling pathway IEA GO:0007186 G-protein coupled receptor protein signaling pathway TAS GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger TAS GO:0007259 JAK-STAT cascade TAS GO:0007568 aging IEA GO:0009408 response to heat IEA GO:0009612 response to mechanical stimulus IEA GO:0009617 response to bacterium IEP GO:0009887 organ morphogenesis TAS GO:0010332 response to gamma radiation IEA GO:0010574 regulation of vascular endothelial growth factor production IEA GO:0010759 positive regulation of macrophage chemotaxis IEA GO:0014823 response to activity IEA GO:0016525 negative regulation of angiogenesis IEA GO:0019079 viral genome replication TAS GO:0019221 cytokine-mediated signaling pathway IDA GO:0019725 cellular homeostasis TAS GO:0030593 neutrophil chemotaxis IEA GO:0031100 organ regeneration IEA GO:0032570 response to progesterone stimulus IEA GO:0033552 response to vitamin B3 IEA GO:0035684 helper T cell extravasation ISS GO:0042493 response to drug IEA GO:0043200 response to amino acid stimulus IEA GO:0043277 apoptotic cell clearance ISS GO:0043615 astrocyte cell migration IDA GO:0045471 response to ethanol IEA GO:0046677 response to antibiotic IEA GO:0048010 vascular endothelial growth factor receptor signaling pathway IEA GO:0048246 macrophage chemotaxis IDA GO:0048247 lymphocyte chemotaxis IEA GO:0050806 positive regulation of synaptic transmission IEA GO:0050870 positive regulation of T cell activation ISS GO:0051384 response to glucocorticoid stimulus IEA GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process ISS GO:0060137 maternal process involved in parturition IEA GO:0070098 chemokine-mediated signaling pathway IEA GO:0071222 cellular response to lipopolysaccharide ISS GO:0071346 cellular response to interferon-gamma ISS GO:0071347 cellular response to interleukin-1 ISS GO:0071356 cellular response to tumor necrosis factor ISS GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages IEA cellular_component GO:0005576 extracellular region TAS GO:0005615 extracellular space IEA GO:0005737 cytoplasm IEA GO:0043025 neuronal cell body IEA molecular_function GO:0001664 G-protein-coupled receptor binding IEA GO:0004672 protein kinase activity TAS GO:0004871 signal transducer activity TAS GO:0005102 receptor binding TAS GO:0008009 chemokine activity IEA GO:0008201 heparin binding IEA GO:0031727 CCR2 chemokine receptor binding ISS GO:0031727 CCR2 chemokine receptor binding TAS

Protein-protein interaction details for CCL2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID DARC Reconstituted Complex physical 13679391 CCL2 Reconstituted Complex physical 7651403 CCR3 Reconstituted Complex physical 8642344 CCL5 Phenotypic Enhancement genetic 11350939 VCAN Reconstituted Complex physical 11083865 CDC6 Affinity Capture-Western physical 21383955 ORC2L Affinity Capture-Western physical 21383955 ORC4L Affinity Capture-Western physical 21383955 MCM2 Affinity Capture-Western physical 21383955 MCM3 Affinity Capture-Western physical 21383955 MCM7 Affinity Capture-Western physical 21383955 CDC45 Affinity Capture-Western physical 21383955 PCNA Affinity Capture-Western physical 21383955 CDC6 Affinity Capture-Western physical 21383955 ORC2L Affinity Capture-Western physical 21383955 ORC4L Affinity Capture-Western physical 21383955 MCM2 Affinity Capture-Western physical 21383955 MCM3 Affinity Capture-Western physical 21383955 MCM7 Affinity Capture-Western physical 21383955 CDC45 Affinity Capture-Western physical 21383955 PCNA Affinity Capture-Western physical 21383955