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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CCL5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6352
Official gene symbolCCL5
Full namechemokine (C-C motif) ligand 5
Aliases,D17S136E,MGC17164,RANTES,SCYA5,SISd,TCP228,
Gene summaryThis gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q11.2-q12
Gene position34207377 - 34198495  Map Viewer
Gene orientationminus
Gene size8883 bp
Gene sequence
OMIM ID187011