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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for CCL5 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002407
dendritic cell chemotaxis
TAS
GO:0002676
regulation of chronic inflammatory response
TAS
GO:0006935
chemotaxis
NAS
GO:0006955
immune response
IEA
GO:0007159
leukocyte cell-cell adhesion
IDA
GO:0007267
cell-cell signaling
IDA
GO:0007568
aging
IEA
GO:0009615
response to virus
TAS
GO:0009617
response to bacterium
IEA
GO:0009651
response to salt stress
IEA
GO:0010535
positive regulation of activation of JAK2 kinase activity
TAS
GO:0010628
positive regulation of gene expression
IEA
GO:0010759
positive regulation of macrophage chemotaxis
IDA
GO:0010820
positive regulation of T cell chemotaxis
IDA
GO:0014068
positive regulation of phosphatidylinositol 3-kinase cascade
IDA
GO:0014070
response to organic cyclic compound
IEA
GO:0014823
response to activity
IEA
GO:0014911
positive regulation of smooth muscle cell migration
IDA
GO:0018894
dibenzo-p-dioxin metabolic process
IEA
GO:0031269
pseudopodium assembly
IEA
GO:0031328
positive regulation of cellular biosynthetic process
IDA
GO:0031584
activation of phospholipase D activity
IDA
GO:0031622
positive regulation of fever generation
IEA
GO:0031667
response to nutrient levels
IEA
GO:0032868
response to insulin stimulus
IEA
GO:0033634
positive regulation of cell-cell adhesion mediated by integrin
IDA
GO:0034112
positive regulation of homotypic cell-cell adhesion
IDA
GO:0034341
response to interferon-gamma
IEA
GO:0042102
positive regulation of T cell proliferation
IDA
GO:0042119
neutrophil activation
IDA
GO:0042327
positive regulation of phosphorylation
IDA
GO:0042493
response to drug
IEA
GO:0042531
positive regulation of tyrosine phosphorylation of STAT protein
IDA
GO:0043526
neuroprotection
IEA
GO:0043623
cellular protein complex assembly
IDA
GO:0043627
response to estrogen stimulus
IEA
GO:0045070
positive regulation of viral genome replication
TAS
GO:0045071
negative regulation of viral genome replication
IDA
GO:0045089
positive regulation of innate immune response
TAS
GO:0045666
positive regulation of neuron differentiation
IEA
GO:0045672
positive regulation of osteoclast differentiation
IEA
GO:0045766
positive regulation of angiogenesis
IEA
GO:0045785
positive regulation of cell adhesion
IDA
GO:0045948
positive regulation of translational initiation
NAS
GO:0046427
positive regulation of JAK-STAT cascade
TAS
GO:0046470
phosphatidylcholine metabolic process
IEA
GO:0048245
eosinophil chemotaxis
IDA
GO:0048246
macrophage chemotaxis
TAS
GO:0048247
lymphocyte chemotaxis
IEA
GO:0048661
positive regulation of smooth muscle cell proliferation
IDA
GO:0050667
homocysteine metabolic process
IEA
GO:0050863
regulation of T cell activation
IDA
GO:0050904
diapedesis
IEA
GO:0050918
positive chemotaxis
IDA
GO:0051262
protein tetramerization
IDA
GO:0051384
response to glucocorticoid stimulus
IEA
GO:0060548
negative regulation of cell death
IEA
GO:0060754
positive regulation of mast cell chemotaxis
IEA
GO:0070098
chemokine-mediated signaling pathway
TAS
GO:0070100
negative regulation of chemokine-mediated signaling pathway
IDA
GO:0070233
negative regulation of T cell apoptosis
IDA
GO:0070234
positive regulation of T cell apoptosis
IDA
GO:0070723
response to cholesterol
IEA
GO:0071222
cellular response to lipopolysaccharide
IEA
GO:0071307
cellular response to vitamin K
IEA
GO:0071315
cellular response to morphine
IEA
GO:0071356
cellular response to tumor necrosis factor
IEA
GO:0071361
cellular response to ethanol
IEA
GO:0071403
cellular response to high density lipoprotein particle stimulus
IEA
GO:0071448
cellular response to alkyl hydroperoxide
IEA
GO:0071560
cellular response to transforming growth factor beta stimulus
IEA
GO:0090026
positive regulation of monocyte chemotaxis
IDA
cellular_component
GO:0005576
extracellular region
TAS
GO:0005615
extracellular space
IEA
GO:0005625
soluble fraction
IEA
GO:0005737
cytoplasm
IEA
molecular_function
GO:0008009
chemokine activity
IDA
GO:0008009
chemokine activity
NAS
GO:0008201
heparin binding
IEA
GO:0030298
receptor signaling protein tyrosine kinase activator activity
IDA
GO:0031726
CCR1 chemokine receptor binding
IDA
GO:0031726
CCR1 chemokine receptor binding
TAS
GO:0031729
CCR4 chemokine receptor binding
TAS
GO:0031730
CCR5 chemokine receptor binding
IPI
GO:0042056
chemoattractant activity
IDA
GO:0042379
chemokine receptor binding
IPI
GO:0042803
protein homodimerization activity
IDA
GO:0043621
protein self-association
IDA
GO:0046817
chemokine receptor antagonist activity
IDA
Protein-protein interaction details for CCL5 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
SDC1
Affinity Capture-Western
physical
14637022
SDC4
Affinity Capture-Western
physical
14637022
CCR5
Affinity Capture-Western
physical
14637022
IL8
Reconstituted Complex
physical
11509627
CCBP2
Reconstituted Complex
physical
9405404
CCR3
Reconstituted Complex
physical
8642344
CCR4
Reconstituted Complex
physical
8573157
CCL2
Phenotypic Enhancement
genetic
11350939
CCR1
Reconstituted Complex
physical
11449371
CCR3
Reconstituted Complex
physical
11449371
CCR5
Reconstituted Complex
physical
11449371
CCR1
Reconstituted Complex
physical
11116158
CCR5
Reconstituted Complex
physical
11116158
VCAN
Reconstituted Complex
physical
11083865