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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CCL5 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002407dendritic cell chemotaxisTAS
GO:0002676regulation of chronic inflammatory responseTAS
GO:0006935chemotaxisNAS
GO:0006955immune responseIEA
GO:0007159leukocyte cell-cell adhesionIDA
GO:0007267cell-cell signalingIDA
GO:0007568agingIEA
GO:0009615response to virusTAS
GO:0009617response to bacteriumIEA
GO:0009651response to salt stressIEA
GO:0010535positive regulation of activation of JAK2 kinase activityTAS
GO:0010628positive regulation of gene expressionIEA
GO:0010759positive regulation of macrophage chemotaxisIDA
GO:0010820positive regulation of T cell chemotaxisIDA
GO:0014068positive regulation of phosphatidylinositol 3-kinase cascadeIDA
GO:0014070response to organic cyclic compoundIEA
GO:0014823response to activityIEA
GO:0014911positive regulation of smooth muscle cell migrationIDA
GO:0018894dibenzo-p-dioxin metabolic processIEA
GO:0031269pseudopodium assemblyIEA
GO:0031328positive regulation of cellular biosynthetic processIDA
GO:0031584activation of phospholipase D activityIDA
GO:0031622positive regulation of fever generationIEA
GO:0031667response to nutrient levelsIEA
GO:0032868response to insulin stimulusIEA
GO:0033634positive regulation of cell-cell adhesion mediated by integrinIDA
GO:0034112positive regulation of homotypic cell-cell adhesionIDA
GO:0034341response to interferon-gammaIEA
GO:0042102positive regulation of T cell proliferationIDA
GO:0042119neutrophil activationIDA
GO:0042327positive regulation of phosphorylationIDA
GO:0042493response to drugIEA
GO:0042531positive regulation of tyrosine phosphorylation of STAT proteinIDA
GO:0043526neuroprotectionIEA
GO:0043623cellular protein complex assemblyIDA
GO:0043627response to estrogen stimulusIEA
GO:0045070positive regulation of viral genome replicationTAS
GO:0045071negative regulation of viral genome replicationIDA
GO:0045089positive regulation of innate immune responseTAS
GO:0045666positive regulation of neuron differentiationIEA
GO:0045672positive regulation of osteoclast differentiationIEA
GO:0045766positive regulation of angiogenesisIEA
GO:0045785positive regulation of cell adhesionIDA
GO:0045948positive regulation of translational initiationNAS
GO:0046427positive regulation of JAK-STAT cascadeTAS
GO:0046470phosphatidylcholine metabolic processIEA
GO:0048245eosinophil chemotaxisIDA
GO:0048246macrophage chemotaxisTAS
GO:0048247lymphocyte chemotaxisIEA
GO:0048661positive regulation of smooth muscle cell proliferationIDA
GO:0050667homocysteine metabolic processIEA
GO:0050863regulation of T cell activationIDA
GO:0050904diapedesisIEA
GO:0050918positive chemotaxisIDA
GO:0051262protein tetramerizationIDA
GO:0051384response to glucocorticoid stimulusIEA
GO:0060548negative regulation of cell deathIEA
GO:0060754positive regulation of mast cell chemotaxisIEA
GO:0070098chemokine-mediated signaling pathwayTAS
GO:0070100negative regulation of chemokine-mediated signaling pathwayIDA
GO:0070233negative regulation of T cell apoptosisIDA
GO:0070234positive regulation of T cell apoptosisIDA
GO:0070723response to cholesterolIEA
GO:0071222cellular response to lipopolysaccharideIEA
GO:0071307cellular response to vitamin KIEA
GO:0071315cellular response to morphineIEA
GO:0071356cellular response to tumor necrosis factorIEA
GO:0071361cellular response to ethanolIEA
GO:0071403cellular response to high density lipoprotein particle stimulusIEA
GO:0071448cellular response to alkyl hydroperoxideIEA
GO:0071560cellular response to transforming growth factor beta stimulusIEA
GO:0090026positive regulation of monocyte chemotaxisIDA
cellular_component
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
GO:0005625soluble fractionIEA
GO:0005737cytoplasmIEA
molecular_function
GO:0008009chemokine activityIDA
GO:0008009chemokine activityNAS
GO:0008201heparin bindingIEA
GO:0030298receptor signaling protein tyrosine kinase activator activityIDA
GO:0031726CCR1 chemokine receptor bindingIDA
GO:0031726CCR1 chemokine receptor bindingTAS
GO:0031729CCR4 chemokine receptor bindingTAS
GO:0031730CCR5 chemokine receptor bindingIPI
GO:0042056chemoattractant activityIDA
GO:0042379chemokine receptor bindingIPI
GO:0042803protein homodimerization activityIDA
GO:0043621protein self-associationIDA
GO:0046817chemokine receptor antagonist activityIDA

Protein-protein interaction details for CCL5 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
SDC1Affinity Capture-Westernphysical14637022
SDC4Affinity Capture-Westernphysical14637022
CCR5Affinity Capture-Westernphysical14637022
IL8Reconstituted Complexphysical11509627
CCBP2Reconstituted Complexphysical9405404
CCR3Reconstituted Complexphysical8642344
CCR4Reconstituted Complexphysical8573157
CCL2Phenotypic Enhancementgenetic11350939
CCR1Reconstituted Complexphysical11449371
CCR3Reconstituted Complexphysical11449371
CCR5Reconstituted Complexphysical11449371
CCR1Reconstituted Complexphysical11116158
CCR5Reconstituted Complexphysical11116158
VCANReconstituted Complexphysical11083865