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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IFIH1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID64135
Official gene symbolIFIH1
Full nameinterferon induced with helicase C domain 1
Aliases,Hlcd,IDDM19,MDA-5,MDA5,MGC133047,
Gene summaryDEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q24
Gene position163175039 - 163123589  Map Viewer
Gene orientationminus
Gene size51451 bp
Gene sequence
OMIM ID606951