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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IFIH1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0009597 detection of virus TAS GO:0032480 negative regulation of type I interferon production TAS GO:0032727 positive regulation of interferon-alpha production TAS GO:0032728 positive regulation of interferon-beta production TAS GO:0042981 regulation of apoptosis IEA GO:0044419 interspecies interaction between organisms IEA GO:0045087 innate immune response TAS cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding IEA GO:0003725 double-stranded RNA binding TAS GO:0004386 helicase activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008270 zinc ion binding IDA GO:0016817 hydrolase activity, acting on acid anhydrides IEA GO:0043021 ribonucleoprotein binding IPI GO:0046872 metal ion binding IEA

Protein-protein interaction details for IFIH1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MAVS Affinity Capture-Western physical 16127453 IDE Affinity Capture-MS physical 21903422 MAVS Affinity Capture-MS physical 21903422 UBC Affinity Capture-Western physical 21910972 SUMO1 Affinity Capture-Western physical 21156324 PIAS2 Affinity Capture-Western physical 21156324 PIAS2 Affinity Capture-Western physical 21156324 UBC Affinity Capture-Western physical 21156324