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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SFRP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6422
Official gene symbolSFRP1
Full namesecreted frizzled-related protein 1
Aliases,FRP,FRP-1,FRP1,FrzA,SARP2,
Gene summaryThis gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq]
LocationChromosome: 8   Locus: 8p12-p11.1
Gene position41166990 - 41119476  Map Viewer
Gene orientationminus
Gene size47515 bp
Gene sequence
OMIM ID604156