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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for SFRP1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001649
osteoblast differentiation
IEP
GO:0001657
ureteric bud development
IEA
GO:0001756
somitogenesis
IEA
GO:0001843
neural tube closure
IEA
GO:0001944
vasculature development
IBA
GO:0001954
positive regulation of cell-matrix adhesion
ISS
GO:0002244
hemopoietic progenitor cell differentiation
IDA
GO:0006309
DNA fragmentation involved in apoptotic nuclear change
IDA
GO:0007420
brain development
IBA
GO:0008284
positive regulation of cell proliferation
IDA
GO:0008285
negative regulation of cell proliferation
IDA
GO:0008406
gonad development
IBA
GO:0008584
male gonad development
IEA
GO:0008585
female gonad development
IEA
GO:0009267
cellular response to starvation
IEP
GO:0009790
embryo development
IBA
GO:0009950
dorsal/ventral axis specification
IDA
GO:0010564
regulation of cell cycle process
IMP
GO:0010629
negative regulation of gene expression
IDA
GO:0010719
negative regulation of epithelial to mesenchymal transition
IDA
GO:0014034
neural crest cell fate commitment
IEA
GO:0014070
response to organic cyclic compound
IDA
GO:0021915
neural tube development
IEA
GO:0022601
menstrual cycle phase
IEP
GO:0030177
positive regulation of Wnt receptor signaling pathway
IDA
GO:0030178
negative regulation of Wnt receptor signaling pathway
IDA
GO:0030178
negative regulation of Wnt receptor signaling pathway
IMP
GO:0030279
negative regulation of ossification
IDA
GO:0030279
negative regulation of ossification
IMP
GO:0030307
positive regulation of cell growth
IDA
GO:0030308
negative regulation of cell growth
IDA
GO:0030336
negative regulation of cell migration
IDA
GO:0030514
negative regulation of BMP signaling pathway
IEA
GO:0032855
positive regulation of Rac GTPase activity
ISS
GO:0033689
negative regulation of osteoblast proliferation
IMP
GO:0035019
somatic stem cell maintenance
IEA
GO:0042493
response to drug
IDA
GO:0043065
positive regulation of apoptosis
IDA
GO:0043065
positive regulation of apoptosis
IMP
GO:0043066
negative regulation of apoptosis
IMP
GO:0044344
cellular response to fibroblast growth factor stimulus
IDA
GO:0044345
stromal-epithelial cell signaling involved in prostate gland development
IEA
GO:0045578
negative regulation of B cell differentiation
IMP
GO:0045600
positive regulation of fat cell differentiation
IDA
GO:0045668
negative regulation of osteoblast differentiation
IEA
GO:0045671
negative regulation of osteoclast differentiation
IEA
GO:0045765
regulation of angiogenesis
ISS
GO:0045880
positive regulation of smoothened signaling pathway
IMP
GO:0045892
negative regulation of transcription, DNA-dependent
IDA
GO:0045892
negative regulation of transcription, DNA-dependent
IMP
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
GO:0045893
positive regulation of transcription, DNA-dependent
IMP
GO:0046676
negative regulation of insulin secretion
IDA
GO:0046851
negative regulation of bone remodeling
IMP
GO:0048147
negative regulation of fibroblast proliferation
IDA
GO:0050679
positive regulation of epithelial cell proliferation
IMP
GO:0050680
negative regulation of epithelial cell proliferation
IDA
GO:0050732
negative regulation of peptidyl-tyrosine phosphorylation
IDA
GO:0051496
positive regulation of stress fiber assembly
ISS
GO:0051894
positive regulation of focal adhesion assembly
ISS
GO:0060070
canonical Wnt receptor signaling pathway
IDA
GO:0060071
Wnt receptor signaling pathway, planar cell polarity pathway
IEA
GO:0060218
hemopoietic stem cell differentiation
IDA
GO:0060346
bone trabecula formation
IEA
GO:0060527
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
IEA
GO:0060687
regulation of branching involved in prostate gland morphogenesis
IEA
GO:0060766
negative regulation of androgen receptor signaling pathway
IDA
GO:0071305
cellular response to vitamin D
IEP
GO:0071347
cellular response to interleukin-1
IEP
GO:0071356
cellular response to tumor necrosis factor
IDA
GO:0071363
cellular response to growth factor stimulus
IDA
GO:0071380
cellular response to prostaglandin E stimulus
IEP
GO:0071391
cellular response to estrogen stimulus
IDA
GO:0071392
cellular response to estradiol stimulus
IEP
GO:0071456
cellular response to hypoxia
IEP
GO:0071481
cellular response to X-ray
IEA
GO:0071504
cellular response to heparin
IDA
GO:0071560
cellular response to transforming growth factor beta stimulus
IEP
GO:0071773
cellular response to BMP stimulus
IEP
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
IDA
GO:0090090
negative regulation of canonical Wnt receptor signaling pathway
IMP
GO:0090263
positive regulation of canonical Wnt receptor signaling pathway
IDA
GO:2000052
positive regulation of non-canonical Wnt receptor signaling pathway
IDA
GO:2000054
negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification
IDA
GO:2000080
negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation
IDA
GO:2000117
negative regulation of cysteine-type endopeptidase activity
IMP
GO:2000270
negative regulation of fibroblast apoptosis
IDA
GO:2000271
positive regulation of fibroblast apoptosis
IDA
cellular_component
GO:0005576
extracellular region
IEA
GO:0005578
proteinaceous extracellular matrix
IDA
GO:0005615
extracellular space
IDA
GO:0005622
intracellular
IDA
GO:0005829
cytosol
IDA
GO:0005886
plasma membrane
IBA
GO:0005886
plasma membrane
ISS
GO:0009986
cell surface
IDA
GO:0031012
extracellular matrix
IDA
GO:0042995
cell projection
ISS
molecular_function
GO:0004197
cysteine-type endopeptidase activity
IMP
GO:0005109
frizzled binding
IPI
GO:0008144
drug binding
IDA
GO:0008201
heparin binding
IDA
GO:0017147
Wnt-protein binding
IPI
GO:0030165
PDZ domain binding
IBA
GO:0042802
identical protein binding
IPI
GO:0042813
Wnt-activated receptor activity
IBA
Protein-protein interaction details for SFRP1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
WNT1
Affinity Capture-Western
physical
10347172
WNT2
Affinity Capture-Western
physical
10347172
FZD6
Affinity Capture-Western
physical
10347172
FZD6
Affinity Capture-Western
physical
10347172
WNT4
Reconstituted Complex
physical
11287180