| Entrez gene ID | | 6472 |
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| Official gene symbol | | SHMT2 |
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| Full name | | serine hydroxymethyltransferase 2 (mitochondrial) |
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| Aliases | | ,GLYA,SHMT, |
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| Gene summary | | This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
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| Location | | Chromosome: 12 Locus: 12q12-q14 |
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| Gene position | | 57623356 - 57628718 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 5363 bp |
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| Gene sequence |
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| OMIM ID | | 138450 |
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