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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SHMT2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006544 glycine metabolic process IEA GO:0006563 L-serine metabolic process IEA GO:0006564 L-serine biosynthetic process IEA GO:0006730 one-carbon metabolic process IDA GO:0008284 positive regulation of cell proliferation IEA GO:0019264 glycine biosynthetic process from serine IEA GO:0051289 protein homotetramerization IEA cellular_component GO:0005739 mitochondrion IDA GO:0005739 mitochondrion IEA GO:0005743 mitochondrial inner membrane IDA GO:0005743 mitochondrial inner membrane IEA GO:0005758 mitochondrial intermembrane space IEA GO:0005759 mitochondrial matrix IDA GO:0005759 mitochondrial matrix IEA GO:0015630 microtubule cytoskeleton IDA GO:0042645 mitochondrial nucleoid IDA molecular_function GO:0003682 chromatin binding IDA GO:0004372 glycine hydroxymethyltransferase activity IDA GO:0004372 glycine hydroxymethyltransferase activity IEA GO:0008168 methyltransferase activity IEA GO:0008732 L-allo-threonine aldolase activity IEA GO:0016597 amino acid binding IEA GO:0016740 transferase activity IEA GO:0030170 pyridoxal phosphate binding IEA GO:0042802 identical protein binding IEA

Protein-protein interaction details for SHMT2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EIF1B Affinity Capture-MS physical 17353931 GNAS Affinity Capture-MS physical 17353931 BRCC3 Affinity Capture-MS physical 19615732 BRE Affinity Capture-MS physical 19615732 C19orf62 Affinity Capture-MS physical 19615732 DDA1 Affinity Capture-MS physical 20562859 UBA5 Affinity Capture-MS physical 20562859 ICT1 Affinity Capture-MS physical 20186120 PPARD Two-hybrid physical 15604093 HDAC5 Affinity Capture-MS physical 21081666 UBC Affinity Capture-MS physical 21987572