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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRIM21 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6737
Official gene symbolTRIM21
Full nametripartite motif-containing 21
Aliases,RNF81,RO52,SSA,SSA1,
Gene summaryThis gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p15.5
Gene position4414926 - 4406127  Map Viewer
Gene orientationminus
Gene size8800 bp
Gene sequence
OMIM ID109092