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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TRIM21 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000209 protein polyubiquitination IDA GO:0006513 protein monoubiquitination IDA GO:0016567 protein ubiquitination IDA GO:0031648 protein destabilization IMP GO:0032088 negative regulation of NF-kappaB transcription factor activity IDA GO:0045787 positive regulation of cell cycle IMP GO:0051865 protein autoubiquitination IDA GO:0070206 protein trimerization IDA GO:0090086 negative regulation of protein deubiquitination IMP cellular_component GO:0000932 cytoplasmic mRNA processing body IEA GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0019005 SCF ubiquitin ligase complex IDA GO:0030529 ribonucleoprotein complex IEA molecular_function GO:0003677 DNA binding IEA GO:0003723 RNA binding IEA GO:0004842 ubiquitin-protein ligase activity IDA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0016874 ligase activity IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for TRIM21 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NIF3L1 Two-hybrid physical 16189514 TRIM21 Two-hybrid physical 11331580 NCOA1 Affinity Capture-MS physical 11971985 NCOA3 Affinity Capture-MS physical 11971985 USP4 Two-hybrid physical 11461834 UBC Affinity Capture-Western physical 18312418 IRF8 Affinity Capture-MS physical 17579016 IRF8 Affinity Capture-Western physical 17579016 IRF8 Reconstituted Complex physical 17579016 IRF8 Biochemical Activity physical 17579016 USP19 Affinity Capture-MS physical 19615732 SKP2 Affinity Capture-MS physical 16880511 SKP2 Affinity Capture-Western physical 16880511 CUL1 Affinity Capture-Western physical 16880511 SKP2 Affinity Capture-Western physical 16880511 SKP1 Affinity Capture-Western physical 16880511 CUL1 Co-fractionation physical 16880511 SKP2 Co-fractionation physical 16880511 SKP1 Co-fractionation physical 16880511 FBXW11 Reconstituted Complex physical 16880511 FBXW11 Affinity Capture-Western physical 16880511 SKP2 Reconstituted Complex physical 16880511 CUL1 Reconstituted Complex physical 16880511 CDKN1B Affinity Capture-Western physical 16880511 USP4 Biochemical Activity physical 16472766 APC Two-hybrid physical 20936779 UBC Affinity Capture-Western physical 12127959 HDAC1 Affinity Capture-MS physical 20585571 TRIM21 Biochemical Activity physical 16403452 UBC Affinity Capture-Western physical 16403452 USP4 Biochemical Activity physical 16403452 UBC Affinity Capture-MS physical 16335966 IRF3 Affinity Capture-MS physical 19265157 IRF3 Affinity Capture-Western physical 19265157 IRF3 Reconstituted Complex physical 19265157 IRF3 Affinity Capture-Western physical 19265157 FADD Affinity Capture-MS physical 21183682 FADD Affinity Capture-Western physical 21183682 FADD Reconstituted Complex physical 21183682 UBC Affinity Capture-Western physical 21183682 EIF2C3 Affinity Capture-MS physical 19167051 EIF2C4 Affinity Capture-MS physical 19167051 IKBKB Affinity Capture-Western physical 19675099 IKBKB Biochemical Activity physical 19675099 TRIM21 Biochemical Activity physical 18022694 UBC Reconstituted Complex physical 18022694 HLA-DRB1 Two-hybrid physical 18022694 HLA-DRB1 Affinity Capture-Western physical 18022694 NCOA3 Affinity Capture-MS physical 16051665 SQSTM1 Affinity Capture-Western physical 19201866 SQSTM1 Affinity Capture-Western physical 19201866 UBC Affinity Capture-Western physical 19201866 YWHAG Affinity Capture-MS physical 15324660 YWHAZ Affinity Capture-MS physical 15324660 IRF7 Affinity Capture-Western physical 20668674 UBC Affinity Capture-MS physical 21987572