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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STAT1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6772
Official gene symbolSTAT1
Full namesignal transducer and activator of transcription 1, 91kDa
Aliases,DKFZp686B04100,ISGF-3,STAT91,
Gene summaryThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q32.2
Gene position191878976 - 191833762  Map Viewer
Gene orientationminus
Gene size45215 bp
Gene sequence
OMIM ID600555