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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TLR1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7096 Official gene symbol TLR1 Full name toll-like receptor 1 Aliases ,CD281,DKFZp547I0610,DKFZp564I0682,KIAA0012,MGC104956,MGC126311,MGC126312,TIL,TIL. LPRS5,rsc786, Gene summary The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq] Location Chromosome: 4   Locus: 4p14 Gene position 38806412 - 38797876  Map Viewer Gene orientation minus Gene size 8537 bp Gene sequence >TLR1:complement(5957238..5965774):Length=8537 ACAGACTGCCAAATGGAACAGACAAGCAGGTTGTCTTGGTAAGCAACACATTCTTTTCTT TTGTAAAAGAAAATAATTGTATAGCTAGTTATTAAGTACAGAAGTCTCAAAAATCTGTGT AAGTCCTGGGTGTTTTTCTAAGTGGGTTATATTTCTGATATGTATATAGTTACTGTGTAG TTTGTACTGGCATTTGTGTATCAGTTCTGAGTCCTAAATCAGAGAAAGTCCCCACACTCC TCTGGGAATAACACCTCGTGTGTGATTTGCTTATAGGAAATATTTTTGAGTTGGGAAATG AATATTTGGGTCACACACGTCTTCTGGTTTTCTTCCAGAGCAGCTGCTAGTTGTTGATTT TGACAGCATTTCTCTTCACCTAATCCCGCCATTTGTATTCTCTTCTCAGTGTTAAAGAAA ATGAGATATAAGTCAGTTACTCCCGGAGGCAATGCTGCTGTTCAGCTCTTCTGTTTTTGT GGCCAGGTTTGTTTCAGTTTTTCTCTCTGGGGCCTTCCCACTAGCTAGTCCTTCTGTTTC TCAGGCCACTAACACTGTTCTGGGGAGCTAGACGTGAGGTAGAATTGCAGGTTTTGAAAA TGTTTCCCAGGCTACATCCAATTTGGTCAAAAGACTTGAAAGTGAATTTGTTTTATAACA AAGCAAGAGTTCACAAAACCGCATAGAAAGCAAAGCAGAACAGTTCTTGAACTGTCTCAG ATTCTTTTAACCTTTGGTTAATAGCTATTTGGTCTTGTGCAGAGAAGGCCCTTAGTAAAT ATTTACAGGACTAAACTTAATGGGCCAGATAGATTGTATGGGTATTGTCCATTAAGACCA GTCAAAGCCTTGATTTGATGCCTCCAAAGTCTCCAAAAGAAGACAAATTAAATGTATTGA TTCATTGTATCATATAATGTGAGGCTAAACCTATCATAATAATGAAAATTCACAGAAGCT CACCTAGAGGCATTTTACACTTTCAAATTAAAGCATCCTTTTCTGCTCAGCTTATTTTTT GGATAGTAAAAGAGTTTAAAGGTTCTAAAATAGATGAGGCTCAGTCATGGTCATTAAGAC GTTGATCAAAAAATTCTTTGGTCTAGGAAACTGAGACATTGATTTTCATGGATTTAGCAA GTTTGGTATATAAAATTCAAAGATCCTGGAAGTATTAAAAATCAGTTATTCCTGTGTATA ACATTTTGATTTCTTAATTATAGAAATAAGAATGGTTTCATAAACTGAGTACTTAAAATT AATGACTTTAAATGAAAGGGCAAGATGGAGGTTAGGCAAATAGAAGATATTTGAGTCAAT TAATTTAGCTCGACATAAAACTGAAGCTATGCTTTCATTAAATGCTTGCGTTAGCAGTGG TGAATCCATATGGGTCGTAGAAACTTAATTCTTGCCTCCTCAGTGGAAAGAATTTGTGTG AGGGGCATAAGGCAGAGTGAGAGACCGAGGCAAGTTTTAGAGTAAGAGAGAGAGTGTCAC GCCCAGGGCCAGGTTCCAGCCCATACTGAGGTCTGAGGGGAGGGGGTGGATGAGCAGATA GCTGAAAGAACACTCAGGGGGCCGTAGGCAGGTGAAAGGTGATTTTATTCAGCAACAGCT CTCATTAGCAGCTTACTTACAGTAGTTCTCTCAGACTGTCCGCCTTGTCCTGGCTGCTTA GTTCGGCAGCTTCCACACACAACTGTGCGTCCGGCTCTCCCTTGCCCTCAGGGTCAGCAG CTTAACTCTTTCTCTCTCTGGGTACAAGCAAGCCGAGCTGTGTCCTGGCTCCCCTCAGTC CATCTGCAAAGATGGACAGCTTTGGCTCTCTCTCTCTCTCTTTCTCTGGCTGCCAATGCA CCTGTACAGCGTCAGCAGGGCAATTATACCATTTACGGACAATAGTGGCTTAGAGCCAAG GGATGAACCTTCCCTATGTTATGGCTATGGTAAGCTTCTCTATGTTATGTCTACATGGCT ATGATAAAAAGTGAGTTATACGCCTGCGCTCTAAACTCGCTGAGTCACTCTGGATGTTTA CCTTGGCCTATCCTTGACCAAAGCACAGCCATATTCCTTACAGAGAGTTTATTAAGAAGT TTTAGATCAGGAACGAAAGGAAATAAAGTACACTTGGAGGAGGGCCAAGTGGGCAACTTG AGAGATCCAAGTGCCCAGTTTAACCTATTACTTGGGGCTTATTTGTTGGCAGGCTTCTGG AGTCTTGCGTCTCTTCTCCCCTGATTCTTCCCTTGGGGTGGGCTGTCTGCATGTGCAGTG GCCTGCCAGCCCTTGGGATGGGCTGCACACACACTGTGTTTACTGAAGTTGTGTACATGC TCATTGGAGACATTTTTCCCTTGCCAGACAAGTCTTCCTAGAGGAAGGTCACATACCCGT TGAAGTCCGCCATTTTGCCTCTTGGTATGCATGCTCAAGCCTGCTTGCCCAGCTCCTGAG AGTTTGTCAGGAGTCTGCTAACCACCAGCTTCAGGTGTGTTTTCTATCTATTAGGAGACT GACTTTCCCTGATGCTGGCTGCAAACAATTATTATTCTAGAGAGACTGTTTTTTTGTTTT TGTTTGTTTGTTTTTGAGACAGAGTCTAGCCCTGTTGCCCAGGCTGGAGTGCAATGGCAT GATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCTTC CCCAGTAGCTGGGATTACAGGCACCTGCCATCACGCCCGGCTAATTTTTGTATTTTTAGT AGAGACAGGGTTTCACCATGCTGGCCAGACTAGTCTCAAACTCCCGACCTCAAGTGATCC ACCTATCTCAGCCTCCCGAAGTGCTGGAATTACAGGCGTGAGCCATGGCCCCCGGCTTAG AGAGACTGTTTAACAACTGCCTGATCATCACCTGATGGTCACCTGATATTCCTGGTTGGG GGGCCCCTCTCCTGTCCTGCTCATGTCTGCCTAAGTACCTACTCTAACACTTGGGGGCAG GCAGTTATATAAATTTATATATTTTTGTGATGATAGCTGTTGTTAAGGGAAAAAGGACAA CTTTCATCTTGCGTGTGGTAGGTTCTGCGAGCCAAGCTCTCGCACTCATGCACGGGGTCC TGTGTGCCTCTGATCACTTTTGAATACCACGCCTGACTGTGCTGATCACTGCTTCCATGA ACTCTGGAGTTGGCTAGGAGGTGGAAAGAGCCTTGATCTGGATTCAGGCATAGGAATAAG CAGGGAACCCCACTTAGGCCTTAAGACCAGGCCACTTTTGCTTCGACCTAGCTTGGCACT GCCCCAGGGTATTATTTTTATTCCCATTATTTTAGTCTGTTTAAATTGCTGTAACAAAGT ACCAGAATGGGTGACTTATAAACAACAGACACTTACTTTTCACAGTTCTGGAAGGTAGAA GTCTAAGATCAGGGTGGTAGTGTTGGGTTCTGGCGAAGGCCCTCTTCTGGTTTGCGGATG CCTCCTTCTTGTATTTTCATATGGCAGAATGACAGCCTGAGGCTCTCTGGGGTCTTTTTT ATAAAGGTACTAATCTGACTCATAAAGGCTCTATTCTTATGACCTAATTACTTCACAATT TTCTCCTGCTAATACCATCACCTTGGGGGTTAGGATTTCAACATAAGAATTTCACAGGGC ACAAACATTCAAGCTATAACATCCATTGAAATATTGCTCCTTGTGTGAGTAGCTCTTTAA GGAAGCTGGAGAGGAAGAATTGGGAAATTTCCGGGTCTTTCAGCCAAATACAGTTAATGT CATAAAAACACCACCTTGACTTTTAACATGAACATTAATGTCTGCATCATCTTCCTTGCT CAGGGTCTTCATGAACACTAATAGGGGTACCAGGCCCTCTTCCTCGTTAGAAGAAATCAG GATAACAAAGGCATATTGGGCACCCCTACAAAAGGGTAAGTCCAAGGAAGGCTCCAAAAC CCAGATAAGTTTGCACATCTAAATTGGGGAACTTTTGTAACCGAGGGTTGTTTGTAGCAG CTAAATTATTTAGGTTCTCTGTGCTCATTGAGATATGGGAGGGGATATGTGAAGAGGAAT TTGGTGCTTTGCTGATACTAATGCCCTGCTTGTCTAATGGTTCTAGGGGATTTTGAATAA GTTCCTTGTGAGAACTGGGTAGCTGTGTAATCACGGCTGAAAGGGTCTCTGGAGGTGAGG ACTGCACACTCTAGAGTTCATCCCAACACAGCTCCCTCTGTTCTCATACGCCACTGGAAT GCTGACCACAAAATGGTGTCTTAGCTAGAGCAGTTTGAATACTGGTACAATAGGCATAAC CTAGAACAGTGCCTACCACTGCATGGAGAATAAATACATATTTGATGAATGAATGAAAAA AGTATTCTGAATAAGAGAGAGGAGGAAACAACTCCCTTTCTCAAAACCTCCCAGTGTTCT CCACCCTCTCATCATTTTTGGAATAGAATCCCAACTCCTTGCAATGATCAACAAAGCCTG AGTGATCTTGGCCCTAACTCCTCTCATCTTCCCTAACTCCTTACTAACATTGACCTTCCC GTTCCTTCTCAGACAAGCCAAGCTCAATTCCATCTCAGGTCCTTTATACTTGCCTTTTCT TTTGCCAGAAATGCTGTAGGTTACCCAGATCTTCCCATAGGTTACTCATTCACTTCATTT TGATTTCTACTCTAGTGTCATCATCTCAAAAAGGCCTTCTCTAACTAATCACTCAAAAAT AGCCACCCCCAAGCACTGTCTCATACCTACAATTTACCCTGCTTTATTTTTCTCTACAGA ACTTATCACTACAGGAACTTGAGTTTAGTCATTCATTTATTTTCTGTCTCCCCACTAGAT AAAAACTCCTTGAGAATTCGGACTTTATCTTGTTCACTGCTCTATCTCCAGTTCTTAAAA CATGGCCAGTAGGTGATCAATAAATACTGGTTGAATAAATAAATGGATGAATAAATGGAT CTTCTGAGAGGCCTTTTATCAGGATCTAATTACCTTTTGAGTAAGACCAAAGTTAGACCC AAACCGTGTATAGGTCATAAAGGGTAATAGAAGAGCAGTCCCAATACCACCATTAGGAAC ACCTCTTGAGAAAGTCATGGGGAGATGTACGTCAAAGAGTGAAAGTACACCAGTTGAGTC TTAGCTGGAGTTCTAAATAATTTTGGGAAGCTTGGGGCCAGAAAACTTTCTATGAACCCA CCTGTATTAGTTTCCTGAGGCTGCTGTAACAGATGATCATAAACGTGGTGGCTTTGCCCT CAACGTTCTGGAGAGCAGAAGTCGAAACTCAAGGTGTCAGCAGGGCCACCATCACTCCAG AGCCTCCTCTAGCTTCTGGCGCCTGTTGATGTTCCTTGCCTTGTAGCTGCTGCACTCCAG TCTCTGCCTCCACTGTCACAAGGCCTTCTCCTCTGTGTCTCAATTGCCTCTTCTCTTGTC TCTTTGTCAAATATCCCTCTGCCTTTCTCTTAAAAAAGCACTTGTCATTGGATTTATGGA CCACCTGGATAATTTGGGATGATCTCCTCATCTCAAGATCCTTAACTTTATTATCTCTGC AAAGACCCCTTTTCTAAGGAAGGTAACATTCATGGTTTCTGGGGATTAGGACATGGTTAA GATGTAGACATATCTTTTGGTGAGCCACCATTCAACCTATTACACCATCCATATTAAAAC TTATTTGATTAGAGCTGGCATCATTATTTACCAATATATATACTTCTCTAGTTTTAGGCC ATGTAACCCAAAAGAATGTAGCCTCCACTTTATAAGTCTGTAACAAAAAAAAGTTTAATG TCAGCCATGACTAATTTCGTGTATTTTAAAAATGTATGTAATGTATTTCATCATTTCATT ATTTTTTTTCTAGAATCTGTATCTGTATCAAGATGATCTGAAGAACAGCTTCTACCTTTA GGAATGTCTAGTGTTCCAAAATGACTAGCATCTTCCATTTTGCCATTATCTTCATGTTAA TACTTCAGATCAGAATACAATTATCTGAAGAAAGTGAATTTTTAGTTGATAGGTCAAAAA ACGGTCTCATCCACGTTCCTAAAGACCTATCCCAGAAAACAACAATCTTAAATATATCGC AAAATTATATATCTGAGCTTTGGACTTCTGACATCTTATCACTGTCAAAACTGAGGATTT TGATAATTTCTCATAATAGAATCCAGTATCTTGATATCAGTGTTTTCAAATTCAACCAGG AATTGGAATACTTGGATTTGTCCCACAACAAGTTGGTGAAGATTTCTTGCCACCCTACTG TGAACCTCAAGCACTTGGACCTGTCATTTAATGCATTTGATGCCCTGCCTATATGCAAAG AGTTTGGCAATATGTCTCAACTAAAATTTCTGGGGTTGAGCACCACACACTTAGAAAAAT CTAGTGTGCTGCCAATTGCTCATTTGAATATCAGCAAGGTCTTGCTGGTCTTAGGAGAGA CTTATGGGGAAAAAGAAGACCCTGAGGGCCTTCAAGACTTTAACACTGAGAGTCTGCACA TTGTGTTCCCCACAAACAAAGAATTCCATTTTATTTTGGATGTGTCAGTCAAGACTGTAG CAAATCTGGAACTATCTAATATCAAATGTGTGCTAGAAGATAACAAATGTTCTTACTTCC TAAGTATTCTGGCGAAACTTCAAACAAATCCAAAGTTATCAAATCTTACCTTAAACAACA TTGAAACAACTTGGAATTCTTTCATTAGGATCCTCCAGCTGGTTTGGCATACAACTGTAT GGTATTTCTCAATTTCAAACGTGAAGCTACAGGGTCAGCTGGACTTCAGAGATTTTGATT ATTCTGGCACTTCCTTGAAGGCCTTGTCTATACACCAAGTTGTCAGCGATGTGTTCGGTT TTCCGCAAAGTTATATCTATGAAATCTTTTCGAATATGAACATCAAAAATTTCACAGTGT CTGGTACACGCATGGTCCACATGCTTTGCCCATCCAAAATTAGCCCGTTCCTGCATTTGG ATTTTTCCAATAATCTCTTAACAGACACGGTTTTTGAAAATTGTGGGCACCTTACTGAGT TGGAGACACTTATTTTACAAATGAATCAATTAAAAGAACTTTCAAAAATAGCTGAAATGA CTACACAGATGAAGTCTCTGCAACAATTGGATATTAGCCAGAATTCTGTAAGCTATGATG AAAAGAAAGGAGACTGTTCTTGGACTAAAAGTTTATTAAGTTTAAATATGTCTTCAAATA TACTTACTGACACTATTTTCAGATGTTTACCTCCCAGGATCAAGGTACTTGATCTTCACA GCAATAAAATAAAGAGCATTCCTAAACAAGTCGTAAAACTGGAAGCTTTGCAAGAACTCA ATGTTGCTTTCAATTCTTTAACTGACCTTCCTGGATGTGGCAGCTTTAGCAGCCTTTCTG TATTGATCATTGATCACAATTCAGTTTCCCACCCATCGGCTGATTTCTTCCAGAGCTGCC AGAAGATGAGGTCAATAAAAGCAGGGGACAATCCATTCCAATGTACCTGTGAGCTAGGAG AATTTGTCAAAAATATAGACCAAGTATCAAGTGAAGTGTTAGAGGGCTGGCCTGATTCTT ATAAGTGTGACTACCCGGAAAGTTATAGAGGAACCCTACTAAAGGACTTTCACATGTCTG AATTATCCTGCAACATAACTCTGCTGATCGTCACCATCGTTGCCACCATGCTGGTGTTGG CTGTGACTGTGACCTCCCTCTGCAGCTACTTGGATCTGCCCTGGTATCTCAGGATGGTGT GCCAGTGGACCCAGACCCGGCGCAGGGCCAGGAACATACCCTTAGAAGAACTCCAAAGAA ATCTCCAGTTTCATGCATTTATTTCATATAGTGGGCACGATTCTTTCTGGGTGAAGAATG AATTATTGCCAAACCTAGAGAAAGAAGGTATGCAGATTTGCCTTCATGAGAGAAACTTTG TTCCTGGCAAGAGCATTGTGGAAAATATCATCACCTGCATTGAGAAGAGTTACAAGTCCA TCTTTGTTTTGTCTCCCAACTTTGTCCAGAGTGAATGGTGCCATTATGAACTCTACTTTG CCCATCACAATCTCTTTCATGAAGGATCTAATAGCTTAATCCTGATCTTGCTGGAACCCA TTCCGCAGTACTCCATTCCTAGCAGTTATCACAAGCTCAAAAGTCTCATGGCCAGGAGGA CTTATTTGGAATGGCCCAAGGAAAAGAGCAAACGTGGCCTTTTTTGGGCTAACTTAAGGG CAGCCATTAATATTAAGCTGACAGAGCAAGCAAAGAAATAGATTACACATCAAGTGAAAA ATATTCCTCCTGTTGATATTGCTGCTTTTGGAAGTTCCAACAATGACTTTATTTTGCATC AGCATAGATGTAAACACAATTGTGAGTGTATGATGTAGGTAAAAATATATACCTTCGGGT CGCAGTTCACCATTTATATGTGGTATTAAAAATTAATGAAATGATATAACTTTGATTTAA ACAGTTCTGACACATAA OMIM ID 601194