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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for TLR1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002224
toll-like receptor signaling pathway
IEA
GO:0002282
microglial cell activation involved in immune response
IEA
GO:0006954
inflammatory response
IEA
GO:0006955
immune response
TAS
GO:0007165
signal transduction
IEA
GO:0032493
response to bacterial lipoprotein
IEA
GO:0042116
macrophage activation
NAS
GO:0042495
detection of triacyl bacterial lipopeptide
IDA
GO:0042535
positive regulation of tumor necrosis factor biosynthetic process
IEA
GO:0042535
positive regulation of tumor necrosis factor biosynthetic process
ISS
GO:0042742
defense response to bacterium
IEA
GO:0045087
innate immune response
IEA
GO:0045410
positive regulation of interleukin-6 biosynthetic process
IEA
GO:0045410
positive regulation of interleukin-6 biosynthetic process
ISS
GO:0052033
pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
IEA
GO:0071727
cellular response to triacyl bacterial lipopeptide
IDA
cellular_component
GO:0005886
plasma membrane
IEA
GO:0005887
integral to plasma membrane
TAS
GO:0016020
membrane
NAS
GO:0030670
phagocytic vesicle membrane
IEA
GO:0031410
cytoplasmic vesicle
IEA
GO:0035354
Toll-like receptor 1-Toll-like receptor 2 protein complex
IDA
molecular_function
GO:0004872
receptor activity
IEA
GO:0004888
transmembrane signaling receptor activity
NAS
GO:0046982
protein heterodimerization activity
IDA
GO:0071723
lipopeptide binding
IEA
Protein-protein interaction details for TLR1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
TLR2
Affinity Capture-Western
physical
12077222
TLR2
Affinity Capture-Western
physical
12077222
TLR4
Affinity Capture-Western
physical
11932926