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Gene information for TOP3A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7156
Official gene symbolTOP3A
Full nametopoisomerase (DNA) III alpha
Aliases,TOP3,
Gene summaryThis gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq]
LocationChromosome: 17   Locus: 17p12-p11.2
Gene position18218321 - 18177235  Map Viewer
Gene orientationminus
Gene size41087 bp
Gene sequence
OMIM ID601243