Entrez gene ID | | 7156 |
Official gene symbol | | TOP3A |
Full name | | topoisomerase (DNA) III alpha |
Aliases | | ,TOP3, |
Gene summary | | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17p12-p11.2 |
Gene position | | 18218321 - 18177235 Map Viewer |
Gene orientation | | minus |
Gene size | | 41087 bp |
Gene sequence |
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OMIM ID | | 601243 |