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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TOP3A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006265 DNA topological change IEA GO:0007126 meiosis TAS cellular_component GO:0005634 nucleus TAS GO:0005694 chromosome IEA GO:0016605 PML body IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding TAS GO:0003916 DNA topoisomerase activity TAS GO:0003917 DNA topoisomerase type I activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008270 zinc ion binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for TOP3A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BLM Reconstituted Complex physical 10734115 BLM Far Western physical 11470874 BLM Affinity Capture-Western physical 11470874 BLM Co-localization physical 11406610 BLM Far Western physical 10825162 BLM Affinity Capture-Western physical 10734115 BLM Far Western physical 10734115 FANCA Affinity Capture-MS physical 12973351 RECQL5 Affinity Capture-Western physical 10710432 BLM Affinity Capture-Western physical 11406610 BLM Affinity Capture-Western physical 11406610 FANCA Affinity Capture-Western physical 21240188 APITD1 Affinity Capture-MS physical 20347429 FANCM Affinity Capture-Western physical 20064461 FANCM Reconstituted Complex physical 20064461 RMI1 Affinity Capture-Western physical 20064461 FANCM Affinity Capture-Western physical 16116422 BLM Affinity Capture-MS physical 12724401 BLM Affinity Capture-Western physical 12724401 FANCA Affinity Capture-MS physical 12724401 FANCA Affinity Capture-Western physical 12724401 RPA1 Affinity Capture-Western physical 12724401 FANCA Affinity Capture-Western physical 12724401 BLM Affinity Capture-Western physical 12724401 RPA1 Affinity Capture-Western physical 12724401 FANCG Affinity Capture-Western physical 12724401