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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NR1H2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7376 Official gene symbol NR1H2 Full name nuclear receptor subfamily 1, group H, member 2 Aliases ,LXR-b,LXRB,NER,NER-I,RIP15,UNR, Gene summary The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM] Location Chromosome: 19   Locus: 19q13.3-q13.3 Gene position 50879685 - 50886267  Map Viewer Gene orientation plus Gene size 6583 bp Gene sequence >NR1H2:23147903..23154485:Length=6583 AAGTTTCACGCTCCGCCCCTCTTCCGGACGTGACGCAAGGGCGGGGTTGCCGGAAGAAGT GGCGAAGTTACTTTTGAGGGTATTTGAGTAGCGGCGGTGTGTCAGGGGCTAAAGAGGAGG ACGAAGAAAAGCAGAGCAAGGGAACCCAGGTAGGTGCACCCGAGAGTGGGGAGACGCAGG AGGAGCCCCGAACCCGGGGCTTCTCGGCGCTCCCCGCGTACTCCGCTCTGCCCCCTTCTC TCCTTCCATTTCCTCCCCTCGGTAATTCGCGCCTCCCGCGGCTGTTTCCAGGGCAACAGG AGTAGTTCACTCCGCGAGAGGCCGTCCACGAGACCCCCGCGCGCAGCCATGAGCCCCGCC CCCCGCTGTTGCTTGGAGAGGGGCGGGACCTGGAGAGAGGTGCGAGGGCGGAGCATGAAT GGAGGAGGCGGGGCGGGGCATGATGGGAGGTGATGGGGCGGGACCTGCAGCGCGGTGCGG GGGCGGGGCATGAAGGGAGGAGGCGGGGCTGGGGGCGGGGCATGATGGGAGGAGATGTGG CGGGGCCTGGAGCGAGGTTGTGGGGGTGCAGTAGGAAGGGAGGAGGCGGGGCGGGGGCGG GGCATGATGGGAGGGGATGGGGACCTGGAGCGAGGTTGTGGGGGTGAGGCTTGGAGGGAG GGATGCATATGGGGCGGGGCAAGGTGTTGGGAGGCCCATGATGGGGGCTTTAGGGGCTGA ACCTGGAAGGTTGAGGGCGGAGCATAGTAGGAGGAGGTGGGGTCAGAATGAGAAATAGGG ATGCTTGGGGCAGAAGTGAGGTAGAGTCTTAAGAAGAGGAGGTGGGGGGAAACTACATGG CATGGAGGCCGTGAAGGCAGAGCATGATTAAAGGAGAATGGGCCCTACCTAGAAAAAGCA GGTGGATTGGACCTGAGGGGGCGGGGCCTACAGCAGGGGCGGGGCTTAAGACCAAGCTGA AGGCTGGCGTGGAACAGAAGGGGGCAGGTCTTGTTAGAAGGATGGGGAGGGTTTGTAGGC TGGCAGGAACCAGGGTTGTGGCTGAGAGTAGGGTCTTTGGAGAGATGGAAAAAAAAGGGA AAGCCCTGTCAGGACCTGTAACTGACCTAACCTAACCCTTCTTAGCCCCACAAGGCTCTC AATCCCCTGTATTCTACAGGCTGCTCCGTGACCCCACCATGTCCTCTCCTACCACGAGTT CCCTGGATACCCCCCTGCCTGGTGAGTGACTCTCTTCCCCACCCAGCCCTTATCACACAC GAGCAGAAGCTCACTGTACCTCTCCCGGATTCCACCCTCTTCCAGGAAATGGCCCCCCTC AGCCTGGCGCCCCTTCTTCTTCACCCACTGTAAAGGAGGAGGGTCCGGAGCCGTGGCCCG GGGGTCCGGACCCTGATGTCCCAGGCACTGATGAGGCCAGCTCAGCCTGCAGCACAGACT GGGGTGAGACAGGGCCCTGGAGTTGATGTGGGGGCTTGGGGAGGGGTTTAGGAAGGGAGA AAGAAATAGAAATGGGAATGGGAGGCCCTGATCTTTGCTTTTTGTTCTTGCTTTCTCCTT AACATATACATCTTTCTAAATTGCAATTTCCCTGAATGTGAGCAGCAACTCCTCTCTCCC TCCATCCTCTGGCTCTTTGCCTGGGGATCTCCTGTGGGCCCATCTCTCTGGTTCCTGTTT CTCCTTGTGGCTTTCTCATGGCCTCTACCTACCCACCCCAGTCATCCCAGATCCCGAAGA GGAACCAGAGCGCAAGCGAAAGAAGGGCCCAGCCCCGAAGATGCTGGGCCACGAGCTTTG CCGTGTCTGTGGGGACAAGGCCTCCGGCTTCCACTACAACGTGCTCAGCTGCGAAGGCTG CAAGGGCTTCTTCCGGCGCAGTGTGGTCCGTGGTGGGGCCAGGCGCTATGCCTGCCGGGG TGGCGGAACCTGCCAGATGGACGCTTTCATGCGGCGCAAGTGCCAGCAGTGCCGGCTGCG CAAGTGCAAGGAGGCAGGGATGAGGGAGCAGTGTGAGTGCAGCGGGAGGGGGCGGTGCCG GCCTGGCCCCCCGCCTAGCCCTGGGGTTCTGCTGAGGCCTGCATCCCCCTACAGGCGTCC TTTCTGAAGAACAGATCCGGAAGAAGAAGATTCGGAAACAGCAGCAGGAGTCACAGTCAC AGTCGCAGTCACCTGTGGGGCCGCAGGGCAGCAGCAGCTCAGCCTCTGGGCCTGGGGCTT CCCCTGGTGGATCTGAGGCAGGCAGCCAGGGCTCCGGGGAAGGCGAGGGTGTCCAGCTAA CAGCGGCTCAAGAACTAATGATCCAGCAGTTGGTGGCGGCCCAACTGCAGTGCAACAAAC GCTCCTTCTCCGACCAGCCCAAAGTCACGGTACTGCCCCCTCCACAACCTTGAGTGTGAC GGTCCCAATGGGGTAGAGCCAGCTGGGCCATCACCCAGGGTGTGGGAGAATGAGGCTCCA GAGGGCAGGGGCTTTGGGAAGAGGATCCCCCAGGGTGCAGGCTTGGCCTCAAGGTGGCCA CCCAGACTTAGGCTCACAAAGACCTGGGAGTGACCCTGGTCTCCTGTGTCCCAGCCCTGG CCCCTGGGCGCAGACCCCCAGTCCCGAGATGCCCGCCAGCAACGCTTTGCCCACTTCACG GAGCTGGCCATCATCTCAGTCCAGGAGATCGTGGACTTCGCTAAGCAAGTGCCTGGTTTC CTGCAGCTGGGCCGGGAGGACCAGATCGCCCTCCTGAAGGCATCCACTATCGAGGTAATG GTCCATCTGCCCACAAGGAACCCCAGAGATAGCTCCAGGACAGATGCTGGGAGCAGAGTT AAGGAAGACCAGTGCTTGCCGTTGTAGGATGACATTCCACGGCGAATAGAGTCTTCTATG AGCCAAGGAGAGAAAGGAAAAAGGGTCTGAGGCTGAGAAAATTGAGGATCAGGCTAGAGG CGCTATTGCAGAGAAAAGTTGCCAAAAAGGCTTTTCAGAGGAGTTAGCATTTGAATCAAA GTAGGGATAACATATAAGTATTGAGCACGTGCTGTATGCCAGGCTCTATTCCAAGTGTTG GCATATGGGGCAAAGAACAAAGCAGATCAAACCCCGTGCCCCAAACCTTGTGCTCACCTG GGGAAAGAGTATCCTAAGGAGATGGGGATGCAGCATGTGCGGAAGCCTGAAGTGGAGAAA GAGCTCGGGCTGTCTCACGTGATGGCTGCACGCTGGTGTGGCTGAGAGAACAGGGGGGAA GGGGACAAGGGATAATCCTGGTGAGATTAGACCCCCATTTGGGCCAGGAGGGGAGGGACT AGCAGCTGAAGGGTCACAGGGCTCAAGCTCCCCCTCCCGCTGCCGCCCTTAGATCATGCT GCTAGAGACAGCCAGGCGCTACAACCACGAGACAGAGTGTATCACCTTCTTGAAGGACTT CACCTACAGCAAGGACGACTTCCACCGTGCAGGTAGGGCCCAGGGGAGGCTTCGGGGAGG CTTGGCGCCCCTGCTGGCTGGAAGACCTGGGGCCAACTCATCCCTGTTGGAGTCTCTGTT TCTTTATCTCCAAAGTTGGGGTGAGGGTTGAGCCAAGGTGAGAGTGAGGTAAGAGTGCAT GTGCCACGTGTGGTGGTGCACGCCAATAGTCCCAGCCACTCGAGGCTGAGGAGGGCAGAT TGCTTGAGGCTATAGTGAGCCGTGATTGTGCGACGGCATTCCAGCCTGGTGACAGAGAAG ACCGTGTCTCTATTTTTTAAAAAAAGCATGTATTGAGTGCCGACTCTGTACATTGGGTTG CAGTGGAAGTTGAGATGGGAGGAGCCCTGTTACCACATCAGGCATCTTGGTGGGCATTAG GAAAAGCATTCCCCGCCCCCGCCAAAACGTGGTCTCACCCAAGGGAGGCGGGCTGGAGCT CGGTCCATTGTGAAGCGGGCAGCCTTCTTTACTGTCTAGGGGAGCACTGCTTCCTGCCCT CTGAGAGCGCTAACCTGCGTGGGTGGGCTTCTGGAAGAAGGCCTGGGCAGTGAGAGGCAC TGCCTAGGAAAAGGGTGGGAGGAGCATTGCTAGTGCTGCAGAGCATGCACCAGGGCCTCG CTCCCTCATTGTCCCACAATCTCTGGGGGACCTCTCTGTATTTCCCGACATCTGTCCAAA CCCCACCCTCTCCCCTTCCTCTTACTCCGGCCCTTTCACCACCCGAGACGGTCCCAGTAA CCCTTTTAGTATGAGCTTAGCAGGGCAGGGCTGCAGGGAAGCGTTTCTGGCAGAGGAGAT TGGCGATTGCAGAGGCCCTGAGGTTGGGGAGAGCTGGTGGTTTGGAGGAACTACAGGGAG GCCCAGGCAGCTGGAGCACAAGGAGATGGGGTGGAGAGGAGGTCGGGAATCCCACCCTAC CCCTTCCCAGCCGCTCCTCTGCCACCACCCTGGAACACTGCCAGGGTCCCCTTGAGGGGC CGCCTGCCTCCACCCCTGCCTGATGGGGCTGCTCACAGCACAGGCAGAAGGGTCCTGTCA GCACTTAAGGCTGCCCACTTCCCTCCTCCGCTCAGAACCCTCCGCGGCTCCCGTCTCACT GGGAGAAGAGCTAGAGTCCTCTCTGTGGCCCACAAAGCCCTTTAGGACCTGGCCTCGCTC ACTCTCTGCCCTCAGCTCTCACCCTCTCCCCCTGTTCCAGCCACTCTGGCCTCTTACTGG CACCCATCCAGCATGCTGCAGCCAAGGGCCTGTGTACTTGGAGTTTCCTCTGCCCAGAAC TAGGGGGACCAACTGGTCCTAGTTTGCCCAGGACCTTCCCAGTTTTAACACTGAAAGTCT CATGGCCTGGGTAGCCCCCGTCCCAAGTCATGGGAACAGCAGACGTTGGTCACCCTCACA ATCCCTCATCTCCTTCGGATTGGTCACTGCTCCAGCGTCACCCAGAGCGCAGCCTTCCCT GCCCGCCTTGTGTAAAATAGAACCATGGCTCAGCAGGGCCCTTCACACTTCTCTGCACTG CCTGGTTCCATTGAACTCACAGCCCTCTGACAGGCTGGGCCTCTTCCTAATGTGTTTGTC TATGACCGGTCCCCTAGGCTCTCAAATGTAAGTGCTGGAGCCTGGCACGTGGCAGGTACT CAGTGACATTTGATGACTGAATGAACAAGTCAGTTTTGGGAATGAGTTTGGGCTTTACCT TGAGCAGTGGAAGCCAGCGCTGGGACCAGCACGATGTGACCTAGGTTTTAAAAGCTTCCC TTTGCCTTTGTGAAGGGGACAAGAATAGGGACTCGGGAAGCTGCAGCCACCGCCCAGGTG GGAAGGGAGGGTGGTGATAGGATAGTAGAAAATACTGAAGAAACATGCACCCTCATTCAT TCCTTCACTGGGCAGCATGTGTGGCACACCTACTACATGCCAGCACTCATGGGCACGGGG CACAGGTGGACAGAAATGACAAGAACGCTGTAATTACTGCTGTGTTCCCAGCCCCAGAGA CTGTGGGCAGCGCCAGGGTCCAGGATGTGGGGCACGGTTTCGGGCTGAGGGAGTCACGGG CTGCCTCCCGCCCCGCAGGCCTGCAGGTGGAGTTCATCAACCCCATCTTCGAGTTCTCGC GGGCCATGCGGCGGCTGGGCCTGGACGACGCTGAGTACGCCCTGCTCATCGCCATCAACA TCTTCTCGGCCGACCGGCCCAACGTGCAGGAGCCGGGCCGCGTGGAGGCGTTGCAGCAGC CCTACGTGGAGGCGCTGCTGTCCTACACGCGCATCAAGAGGCCGCAGGTAGGGCCCCGCA GAGCCTCTGCGCAGAGCCAACTACGTCCCGCGGCCCACGTGGTCCGTTCAGGCTGGGTTC TGCCAGCCACACTGCCCTCCCCTCCGCAGAGTCTTTCCTCAGGCCCCACCCTGCTCGACT GGGAGCCAGGTCTAGTCCAAGCACAGAGGCGGGCCCCACGCTGGCTCCCACGCCTGGTCG GGGAGGGGCCCTCCTTTCTGTTGGGGTGGGCCTCCCAAAGCCTGGCAGGGCAGGGGCTCA GCCAGCGCCCACCTGCCTCCTCCCTCAGGACCAGCTGCGCTTCCCGCGCATGCTCATGAA GCTGGTGAGCCTGCGCACGCTGAGCTCTGTGCACTCGGAGCAGGTCTTCGCCTTGCGGCT CCAGGACAAGAAGCTGCCGCCTCTGCTGTCGGAGATCTGGGACGTCCACGAGTGAGGGGC TGGCCACCCAGCCCCACAGCCTTGCCTGACCACCCTCCAGCAGATAGACGCCGGCACCCC TTCCTCTTCCTAGGGTGGAAGGGGCCCTGGGCCGAGCCTGTAGACCTATCGGCTCTCATC CCTTGGGATAAGCCCCAGTCCAGGTCCAGGAGGCTCCCTCCCTGCCCAGCGAGTCTTCCA GAAGGGGTGAAAGGGTTGCAGGTCCCGACCACTGACCCTTCCCGGCTGCCCTCCCTCCCC AGCTTACACCTCAAGCCCAGCACGCAGTGCACCTTGAACAGAGGGAGGGGAGGACCCATG GCTCTCCCCCCTAGCCCGGGAGACCAGGGCCTTCCTCTTCCTCTGCTTTTATTTAATAAA AACTAAAAACAGAAACAGGAAAATAAAATATGAATACAATCCA OMIM ID 600380