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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NR1H2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0010467gene expressionTAS
GO:0010745negative regulation of macrophage derived foam cell differentiationIC
GO:0010867positive regulation of triglyceride biosynthetic processIMP
GO:0010875positive regulation of cholesterol effluxIMP
GO:0010887negative regulation of cholesterol storageIMP
GO:0030522intracellular receptor mediated signaling pathwayTAS
GO:0032270positive regulation of cellular protein metabolic processIMP
GO:0032369negative regulation of lipid transportIMP
GO:0032376positive regulation of cholesterol transportIDA
GO:0034339regulation of transcription from RNA polymerase II promoter by nuclear hormone receptorTAS
GO:0044255cellular lipid metabolic processIEA
GO:0045723positive regulation of fatty acid biosynthetic processIMP
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0048384retinoic acid receptor signaling pathwayIEA
GO:0048550negative regulation of pinocytosisIMP
GO:0051006positive regulation of lipoprotein lipase activityIMP
GO:0060336negative regulation of interferon-gamma-mediated signaling pathwayNAS
cellular_component
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005654nucleoplasmTAS
GO:0005737cytoplasmIDA
molecular_function
GO:0003677DNA bindingIEA
GO:0003677DNA bindingTAS
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0003707steroid hormone receptor activityIEA
GO:0004872receptor activityIEA
GO:0004879ligand-dependent nuclear receptor activityTAS
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0043565sequence-specific DNA bindingIEA
GO:0046872metal ion bindingIEA
GO:0046965retinoid X receptor bindingIEA

Protein-protein interaction details for NR1H2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
MDFITwo-hybridphysical16189514
NCOA6Two-hybridphysical11158331
NCOA6Reconstituted Complexphysical11158331
RXRBReconstituted Complexphysical10187832
NR0B2Reconstituted Complexphysical12198243
RXRATwo-hybridphysical7760852
RXRAReconstituted Complexphysical7760852
SIRT1Affinity Capture-Westernphysical17936707
HDAC4Biochemical Activityphysical17218271
HDAC4Reconstituted Complexphysical17218271
NCOR1Two-hybridphysical12663743
SMARCA4Affinity Capture-Westernphysical15774904
ZXDCTwo-hybridphysical15604093
NRIP1Two-hybridphysical15604093
MED1Two-hybridphysical15604093
NCOR2Two-hybridphysical15604093
NCOA3Two-hybridphysical15604093
NCOA6Two-hybridphysical15604093
RARATwo-hybridphysical15604093
NPYTwo-hybridphysical15604093
FOXO3Two-hybridphysical15604093
RXRATwo-hybridphysical15604093
SCG5Two-hybridphysical15604093
UBE2ITwo-hybridphysical15604093
SRCTwo-hybridphysical15604093
NCOR2Two-hybridphysical15604093
NCOR1Two-hybridphysical15604093
NCOA3Two-hybridphysical15604093
RXRGTwo-hybridphysical15604093
TMEM161ATwo-hybridphysical15604093
ING3Two-hybridphysical15604093
RXRBTwo-hybridphysical15604093
PCDH17Two-hybridphysical15604093
VDRTwo-hybridphysical15604093
RXRBTwo-hybridphysical15604093
DUSP12Two-hybridphysical21900206
SPRY2Two-hybridphysical21900206
RXRGTwo-hybridphysical21900206
C14orf1Two-hybridphysical21900206
ROBO2Two-hybridphysical21900206
CHD3Two-hybridphysical21900206
MPP1Two-hybridphysical21900206
SMPD1Two-hybridphysical21900206
CSADTwo-hybridphysical21900206
VIMTwo-hybridphysical21900206
COL4A5Two-hybridphysical21900206
SORBS2Two-hybridphysical21900206
BAT3Two-hybridphysical21900206
UBE2D1Two-hybridphysical21900206
RMI1Two-hybridphysical21900206
HMGXB4Two-hybridphysical21900206
FAF1Two-hybridphysical21900206
CORO2AAffinity Capture-Westernphysical21331046
CORO2AAffinity Capture-Westernphysical21331046
SENP3Affinity Capture-Westernphysical21331046
SENP3Affinity Capture-Westernphysical21331046