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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for XRCC1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7515
Official gene symbolXRCC1
Full nameX-ray repair complementing defective repair in Chinese hamster cells 1
Aliases,RCC,
Gene summaryThe protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
LocationChromosome: 19   Locus: 19q13.2
Gene position44079730 - 44047464  Map Viewer
Gene orientationminus
Gene size32267 bp
Gene sequence
OMIM ID194360