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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for XRCC1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000012 single strand break repair IEA GO:0001666 response to hypoxia IEA GO:0006281 DNA repair TAS GO:0006284 base-excision repair TAS GO:0010033 response to organic substance IEA GO:0042493 response to drug IEA cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS molecular_function GO:0003684 damaged DNA binding IEA GO:0005515 protein binding IPI

Protein-protein interaction details for XRCC1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID LIG3 Two-hybrid physical 11163244 PNKP Two-hybrid physical 11163244 APTX Affinity Capture-Western physical 15555565 APTX Two-hybrid physical 15555565 APTX Affinity Capture-Western physical 15555565 APTX Two-hybrid physical 15555565 POLB Two-hybrid physical 15520167 PNKP Affinity Capture-MS physical 17353931 LIG3 Affinity Capture-MS physical 17353931 PNKP Affinity Capture-MS physical 17353931 NEIL1 Reconstituted Complex physical 15260972 PCNA Affinity Capture-Western physical 15107487 PCNA Affinity Capture-Western physical 15107487 PCNA Reconstituted Complex physical 15107487 POLB Reconstituted Complex physical 15107487 PCNA Co-localization physical 15107487 PCNA FRET physical 15107487 APTX Affinity Capture-Western physical 15044383 PARP1 Affinity Capture-Western physical 15044383 APTX Affinity Capture-Western physical 15044383 TP53 Affinity Capture-Western physical 15044383 PARP1 Affinity Capture-Western physical 15044383 APTX Reconstituted Complex physical 15044383 OGG1 Reconstituted Complex physical 12933815 OGG1 Two-hybrid physical 12933815 POLB Reconstituted Complex physical 8978692 POLB Far Western physical 8978692 LIG3 Co-purification physical 8264637 LIG3 Affinity Capture-Western physical 9136882 LIG3 Reconstituted Complex physical 11352725 POLB Reconstituted Complex physical 11467963 POLB Affinity Capture-Western physical 11467963 PARP1 Two-hybrid physical 9584196 PARP1 Reconstituted Complex physical 9584196 LIG3 Reconstituted Complex physical 9705932 APEX1 Two-hybrid physical 11707423 APEX1 Far Western physical 11707423 PARP2 Affinity Capture-Western physical 11948190 PARP2 Affinity Capture-Western physical 11948190 PNKP Affinity Capture-Western physical 11163244 PNKP Affinity Capture-Western physical 11163244 PNKP Far Western physical 11163244 CHD1L Affinity Capture-Western physical 19661379 NCAPG Affinity Capture-Western physical 16543152 PARP1 Affinity Capture-Western physical 20303835 PARP1 Affinity Capture-Western physical 20302655 RAN Affinity Capture-Western physical 20805321 PCNA Affinity Capture-Western physical 20227374 LIG3 Affinity Capture-Western physical 20227374 POLK Affinity Capture-Western physical 20227374 POLD1 Affinity Capture-Western physical 20227374 POLK Affinity Capture-Western physical 20227374 ARL6IP5 Affinity Capture-Western physical 19208635 ARL6IP5 Affinity Capture-Western physical 19208635 PARP1 Affinity Capture-Western physical 12897160 RNF146 Affinity Capture-MS physical 21825151 RNF146 Affinity Capture-Western physical 21825151 RNF146 Biochemical Activity physical 21825151