Entrez gene ID | | 7849 |
Official gene symbol | | PAX8 |
Full name | | paired box 8 |
Aliases | | ,-, |
Gene summary | | This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q12-q14 |
Gene position | | 114036498 - 113973574 Map Viewer |
Gene orientation | | minus |
Gene size | | 62925 bp |
Gene sequence |
| |
|