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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PAX8 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001655urogenital system developmentISS
GO:0001658branching involved in ureteric bud morphogenesisIEP
GO:0001822kidney developmentIEP
GO:0001823mesonephros developmentISS
GO:0003337mesenchymal to epithelial transition involved in metanephros morphogenesisIEP
GO:0006351transcription, DNA-dependentIDA
GO:0006351transcription, DNA-dependentTAS
GO:0006355regulation of transcription, DNA-dependentTAS
GO:0007275multicellular organismal developmentIEA
GO:0007417central nervous system developmentIEP
GO:0009653anatomical structure morphogenesisTAS
GO:0030154cell differentiationIEA
GO:0030878thyroid gland developmentIEP
GO:0030878thyroid gland developmentIMP
GO:0039003pronephric field specificationISS
GO:0042472inner ear morphogenesisISS
GO:0042981regulation of apoptosisISS
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentISS
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0048793pronephros developmentISS
GO:0071371cellular response to gonadotropin stimulusIDA
GO:0071599otic vesicle developmentIEP
GO:0072108positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisISS
GO:0072164mesonephric tubule developmentIEA
GO:0072205metanephric collecting duct developmentISS
GO:0072207metanephric epithelium developmentIEP
GO:0072221metanephric distal convoluted tubule developmentISS
GO:0072278metanephric comma-shaped body morphogenesisIEP
GO:0072284metanephric S-shaped body morphogenesisIEP
GO:0072289metanephric nephron tubule formationISS
GO:0072305negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesisISS
GO:0072307regulation of metanephric nephron tubule epithelial cell differentiationISS
GO:0090190positive regulation of branching involved in ureteric bud morphogenesisISS
GO:2000594positive regulation of metanephric DCT cell differentiationISS
GO:2000611positive regulation of thyroid hormone generationIMP
GO:2000612regulation of thyroid-stimulating hormone secretionIMP
cellular_component
GO:0005634nucleusIDA
GO:0005654nucleoplasmISS
GO:0005730nucleolusIDA
molecular_function
GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIDA
GO:0003677DNA bindingIDA
GO:0003677DNA bindingIMP
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0004996thyroid-stimulating hormone receptor activityTAS
GO:0005515protein bindingIPI
GO:0043565sequence-specific DNA bindingIEA
GO:0044212transcription regulatory region DNA bindingIDA

Protein-protein interaction details for PAX8 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
NKX2-1Reconstituted Complexphysical12441357
NKX2-1Affinity Capture-Westernphysical12441357
POU2AF1Two-hybridphysical20211142