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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CXCR4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7852 Official gene symbol CXCR4 Full name chemokine (C-X-C motif) receptor 4 Aliases ,CD184,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM, Gene summary This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] Location Chromosome: 2   Locus: 2q21 Gene position 136875725 - 136871919  Map Viewer Gene orientation minus Gene size 3807 bp Gene sequence >CXCR4:complement(26620582..26624388):Length=3807 AACTTCAGTTTGTTGGCTGCGGCAGCAGGTAGCAAAGTGACGCCGAGGGCCTGAGTGCTC CAGTAGCCACCGCATCTGGAGAACCAGCGGTTACCATGGAGGGGATCAGTGTAAGTCCAG TTTCAACCTGCTTTGTCATAAATGTACAAACGTTTGAACTTAGAGCGCAGCCCCTCTCCG AGCGGGCAGAAGCGGCCAGGACATTGGAGGTACCCGTACTCCAAAAAAGGGTCACCGAAA GGAGTTTTCTTGACCATGCCTATATAGTGCGGGTGGGTGGGGGGGGAGCAGGATTGGAAT CTTTTTCTCTGTGAGTCGAGGAGAAACGACTGGAAAGAGCGTTCCAGTGGCTGCATGTGT CTCCCCCTTGAGTCCCGCCGCGCGCGGCGGCTTGCACGCTGTTTGCAAACGTAAGAACAT TCTGTGCACAAGTGCAGAGAAGGCGTGCGCGCTGCCTCGGGACTCAGACCACCGGTCTCT TCCTTGGGGAAGCGGGGATGTCTTGGAGCGAGTTACATTGTCTGAATTTAGAGGCGGAGG GCGGCGTGCCTGGGCTGAGTTCCCAGGAGGAGATTGCGCCCGCTTTAACTTCGGGGTTAA GCGCCTGGTGACTGTTCTTGACACTGGGTGCGTGTTTGTTAAACTCTGTGCGGCCGACGG AGCTGTGCCAGTCTCCCAGCACAGTAGGCAGAGGGCGGGAGAGGCGGGTGGACCCACCGC GCCGATCCTCTGAGGGGATCGAGTGGTGGCAGCAGCTAGGAGTTGATCCGCCCGCGCGCT TTGGGTTTGAGGGGGAAAACCTTCCCGCCGTCCGAAGCGCGCCTCTTCCCCACGGCCGCG AGTGGGTCCTGCAGTTCGAGAGTTTGGGGTCGTGCAGAGGTCAGCGGAGTGGTTTGACCT CCCCTTTGACACCGCGCAGCTGCCAGCCCTGAGATTTGCGCTCCGGGGATAGGAGCGGGT ACGGGGTGAGGGGCGGGGGCGGTTAAGACCGCACCTGGGCTGCCAGGTCGCCGCCGCGAA GACTGGCAGGTGCAAGTGGGGAAACCGTTTGGCTCTCTCCGAGTCCAGTTGTGATGTTTA ACCGTCGGTGGTTTCCAGAAACCTTTTGAAACCCTCTTGCTAGGGAGTTTTTGGTTTCCT GCAGCGGCGCGCAATTCAAAGACGCTCGCGGCGGAGCCGCCCAGTCGCTCCCCAGCACCC TGTGGGACAGAGCCTGGCGTGTCGCCCAGCGGAGCCCCTGCAGCGCTGCTTGCGGGCGGT TGGCGTGGGTGTAGTGGGCAGCCGCGGCGGCCCGGGGCTGGACGACCCGGCCCCCCGCGT GCCCACCGCCTGGAGGCTTCCAGCTGCCCACCTCCGGCCGGGTTAACTGGATCAGTGGCG GGGTAATGGGAAGCCACCCGGGAGAGTGAGGAAATGAAACTTGGGGCGAGGACCACGGGT GCAGACCCCGTTACCTTCTCCACCCAGGAAAATGCCCCGCTCCCTAACGTCCCAAACGCG CCAAGTGATAAACACGAGGATGGCAAGAGACCCACACACCGGAGGAGCGCCCGCTTGGGG GAGGAGGTGCCGTTTGTTCATTTTCTGACACTCCCGCCCAATATACCCCAAGCACCGAAG GGCCTTCGTTTTAAGACCGCATTCTCTTTACCCACTACAAGTTGCTTGAAGCCCAGAATG GTTTGTATTTAGGCAGGCGTGGGAAAATTAAGTTTTTGCGCTTTAGGAGAATGAGTCTTT GCAACGCCCCCGCCCTCCCCCCGTGATCCTCCCTTCTCCCCTCTTCCCTCCCTGGGCGAA AAACTTCTTACAAAAAGTTAATCACTGCCCCTCCTAGCAGCACCCACCCCACCCCCCACG CCGCCTGGGAGTGGCCTCTTTGTGTGTATTTTTTTTTTCCTCCTAAGGAAGGTTTTTTTT CTTCCCTCTAGTGGGCGGGGCAGAGGAGTTAGCCAAGATGTGACTTTGAAACCCTCAGCG TCTCAGTGCCCTTTTGTTCTAAACAAAGAATTTTGTAATTGGTTCTACCAAAGAAGGATA TAATGAAGTCACTATGGGAAAAGATGGGGAGGAGAGTTGTAGGATTCTACATTAATTCTC TTGTGCCCTTAGCCCACTACTTCAGAATTTCCTGAAGAAAGCAAGCCTGAATTGGTTTTT TAAATTGCTTTAAAAATTTTTTTTAACTGGGTTAATGCTTGCTGAATTGGAAGTGAATGT CCATTCCTTTGCCTCTTTTGCAGATATACACTTCAGATAACTACACCGAGGAAATGGGCT CAGGGGACTATGACTCCATGAAGGAACCCTGTTTCCGTGAAGAAAATGCTAATTTCAATA AAATCTTCCTGCCCACCATCTACTCCATCATCTTCTTAACTGGCATTGTGGGCAATGGAT TGGTCATCCTGGTCATGGGTTACCAGAAGAAACTGAGAAGCATGACGGACAAGTACAGGC TGCACCTGTCAGTGGCCGACCTCCTCTTTGTCATCACGCTTCCCTTCTGGGCAGTTGATG CCGTGGCAAACTGGTACTTTGGGAACTTCCTATGCAAGGCAGTCCATGTCATCTACACAG TCAACCTCTACAGCAGTGTCCTCATCCTGGCCTTCATCAGTCTGGACCGCTACCTGGCCA TCGTCCACGCCACCAACAGTCAGAGGCCAAGGAAGCTGTTGGCTGAAAAGGTGGTCTATG TTGGCGTCTGGATCCCTGCCCTCCTGCTGACTATTCCCGACTTCATCTTTGCCAACGTCA GTGAGGCAGATGACAGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTGGTTG TGTTCCAGTTTCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCT GCTATTGCATTATCATCTCCAAGCTGTCACACTCCAAGGGCCACCAGAAGCGCAAGGCCC TCAAGACCACAGTCATCCTCATCCTGGCTTTCTTCGCCTGTTGGCTGCCTTACTACATTG GGATCAGCATCGACTCCTTCATCCTCCTGGAAATCATCAAGCAAGGGTGTGAGTTTGAGA ACACTGTGCACAAGTGGATTTCCATCACCGAGGCCCTAGCTTTCTTCCACTGTTGTCTGA ACCCCATCCTCTATGCTTTCCTTGGAGCCAAATTTAAAACCTCTGCCCAGCACGCACTCA CCTCTGTGAGCAGAGGGTCCAGCCTCAAGATCCTCTCCAAAGGAAAGCGAGGTGGACATT CATCTGTTTCCACTGAGTCTGAGTCTTCAAGTTTTCACTCCAGCTAACACAGATGTAAAA GACTTTTTTTTATACGATAAATAACTTTTTTTTAAGTTACACATTTTTCAGATATAAAAG ACTGACCAATATTGTACAGTTTTTATTGCTTGTTGGATTTTTGTCTTGTGTTTCTTTAGT TTTTGTGAAGTTTAATTGACTTATTTATATAAATTTTTTTTGTTTCATATTGATGTGTGT CTAGGCAGGACCTGTGGCCAAGTTCTTAGTTGCTGTATGTCTCGTGGTAGGACTGTAGAA AAGGGAACTGAACATTCCAGAGCGTGTAGTGAATCACGTAAAGCTAGAAATGATCCCCAG CTGTTTATGCATAGATAATCTCTCCATTCCCGTGGAACGTTTTTCCTGTTCTTAAGACGT GATTTTGCTGTAGAAGATGGCACTTATAACCAAAGCCCAAAGTGGTATAGAAATGCTGGT TTTTCAGTTTTCAGGAGTGGGTTGATTTCAGCACCTACAGTGTACAGTCTTGTATTAAGT TGTTAATAAAAGTACATGTTAAACTTA OMIM ID 162643