Entrez gene ID | | 8554 |
Official gene symbol | | PIAS1 |
Full name | | protein inhibitor of activated STAT, 1 |
Aliases | | ,DDXBP1,GBP,GU/RH-II,MGC141878,MGC141879,ZMIZ3, |
Gene summary | | This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q |
Gene position | | 68346572 - 68480413 Map Viewer |
Gene orientation | | plus |
Gene size | | 133842 bp |
Gene sequence |
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OMIM ID | | 603566 |
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