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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PIAS1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA GO:0007259 JAK-STAT cascade TAS GO:0019221 cytokine-mediated signaling pathway TAS GO:0030521 androgen receptor signaling pathway NAS GO:0033235 positive regulation of protein sumoylation IDA GO:0045893 positive regulation of transcription, DNA-dependent NAS GO:0060333 interferon-gamma-mediated signaling pathway TAS GO:0060334 regulation of interferon-gamma-mediated signaling pathway TAS cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS GO:0016607 nuclear speck IEA molecular_function GO:0003676 nucleic acid binding IEA GO:0003677 DNA binding IEA GO:0003713 transcription coactivator activity NAS GO:0003714 transcription corepressor activity TAS GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0019789 SUMO ligase activity IDA GO:0019899 enzyme binding IPI GO:0031625 ubiquitin protein ligase binding IEA GO:0046872 metal ion binding IEA GO:0050681 androgen receptor binding NAS

Protein-protein interaction details for PIAS1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID STAT1 Two-hybrid physical 10805787 DNMT3A Two-hybrid physical 14752048 DNMT3A Affinity Capture-Western physical 14752048 DNMT3A Affinity Capture-Western physical 14752048 DNMT3A Reconstituted Complex physical 14752048 STAB2 Affinity Capture-Western physical 14701874 UBE2I Two-hybrid physical 14609633 SUMO1 Two-hybrid physical 14609633 SP3 Two-hybrid physical 12356736 SP3 Reconstituted Complex physical 12356736 UBE2I Reconstituted Complex physical 12356736 TP53 Two-hybrid physical 10380882 CSRP2 Two-hybrid physical 11672422 AR Two-hybrid physical 11117529 SUMO1 Two-hybrid physical 11583632 UBE2I Two-hybrid physical 11583632 TP53 Reconstituted Complex physical 11583632 TP53 Biochemical Activity physical 11583632 STAT1 Reconstituted Complex physical 10805787 MX1 Two-hybrid physical 11716541 SUMO2 Reconstituted Complex physical 18806873 SIAH1 Two-hybrid physical 17533377 SIAH2 Two-hybrid physical 17533377 AKT1 Two-hybrid physical 17533377 SIAH2 Reconstituted Complex physical 17533377 SIAH1 Reconstituted Complex physical 17533377 SIAH2 Affinity Capture-Western physical 17533377 SIAH2 Biochemical Activity physical 17533377 ZMIZ2 Affinity Capture-Western physical 20159969 SUMO2 Co-localization physical 20016603 SUMO3 Co-localization physical 20016603 BRCA1 Co-localization physical 20016603 BRCA1 Biochemical Activity physical 20016594 BRCA1 Co-localization physical 20016594 MBD1 Affinity Capture-Western physical 19074829 UBE2I Two-hybrid physical 20936779 CREB1 Two-hybrid physical 20936779 SREBF2 Two-hybrid physical 20936779 GLUL Two-hybrid physical 20936779 MITF Reconstituted Complex physical 16029420 MBD1 Two-hybrid physical 17066076 MBD1 Reconstituted Complex physical 17066076 SUMO2 Affinity Capture-MS physical 19394292 NCOR1 Reconstituted Complex physical 16421255 NCOR1 Two-hybrid physical 16421255 NCOR1 Affinity Capture-Western physical 16421255 NCOR1 Affinity Capture-Western physical 16421255 PPARG Affinity Capture-Western physical 16127449 PPARG Co-localization physical 16127449 TRIM27 Two-hybrid physical 15907835 TRIM27 Affinity Capture-Western physical 15907835 ZNF76 Affinity Capture-Western physical 15280358 ZNF76 Two-hybrid physical 15280358 JUN Reconstituted Complex physical 11867732 TP53 Reconstituted Complex physical 11867732 HIC1 Biochemical Activity physical 17283066 DDX5 Affinity Capture-Western physical 17369852 DDX5 Reconstituted Complex physical 17369852 SATB1 Two-hybrid physical 20351170 SATB1 Affinity Capture-Western physical 20351170 SATB1 Affinity Capture-Western physical 20351170 SATB1 Reconstituted Complex physical 20351170 SATB1 Reconstituted Complex physical 20351170 MAML1 Biochemical Activity physical 20203086 DCLRE1A Two-hybrid physical 15572677 DCLRE1A Affinity Capture-Western physical 15572677 DCLRE1A Affinity Capture-Western physical 15572677 UBE2I Affinity Capture-Western physical 19965618 NEDD8 Affinity Capture-MS physical 18274552 DNMT3A Affinity Capture-Western physical 20966256 DNMT3B Affinity Capture-Western physical 20966256 DNMT3A Co-localization physical 20966256 DNMT3B Co-localization physical 20966256 RBBP6 Two-hybrid physical 18624398 SAFB Affinity Capture-Western physical 21527249 ESR1 Two-hybrid physical 15666801