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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RUNX3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID864
Official gene symbolRUNX3
Full namerunt-related transcription factor 3
Aliases,AML2,CBFA3,FLJ34510,MGC16070,PEBP2aC,
Gene summaryThis gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36
Gene position25291501 - 25226002  Map Viewer
Gene orientationminus
Gene size65500 bp
Gene sequence
OMIM ID600210