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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for RUNX3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006355 regulation of transcription, DNA-dependent NAS GO:0006355 regulation of transcription, DNA-dependent TAS GO:0006366 transcription from RNA polymerase II promoter TAS GO:0006468 protein phosphorylation IDA GO:0006917 induction of apoptosis ISS GO:0008283 cell proliferation NAS GO:0045786 negative regulation of cell cycle ISS GO:0048935 peripheral nervous system neuron development TAS GO:0050680 negative regulation of epithelial cell proliferation ISS cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005634 nucleus NAS GO:0005737 cytoplasm IDA molecular_function GO:0003677 DNA binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0005524 ATP binding NAS

Protein-protein interaction details for RUNX3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PHB2 Affinity Capture-MS physical 17353931 YAP1 Reconstituted Complex physical 10228168 SMAD3 Affinity Capture-Western physical 10531362 SMAD1 Affinity Capture-Western physical 10531362 SMAD2 Affinity Capture-Western physical 10531362 SMAD5 Affinity Capture-Western physical 10531362 TLE1 Two-hybrid physical 9751710 TLE1 Far Western physical 9751710 SP110 Two-hybrid physical 20211142 SUV39H1 Affinity Capture-Western physical 16652147 EP300 Affinity Capture-Western physical 15138260 EP300 Affinity Capture-Western physical 15138260 CBFB Affinity Capture-Western physical 15138260 SMAD3 Affinity Capture-Western physical 15138260 HDAC9 Affinity Capture-Western physical 15138260 SMURF1 Affinity Capture-Western physical 15138260 SMURF2 Affinity Capture-Western physical 15138260 UBC Affinity Capture-Western physical 15138260 EZH2 Affinity Capture-Western physical 20714105 EZH2 Affinity Capture-Western physical 20714105 MDM2 Affinity Capture-Western physical 19808967 UBC Affinity Capture-Western physical 19808967 UBC Affinity Capture-Western physical 19351720 UBC Affinity Capture-Western physical 20676134