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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAP3K14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9020
Official gene symbolMAP3K14
Full namemitogen-activated protein kinase kinase kinase 14
Aliases,FTDCR1B,HS,HSNIK,NIK,
Gene summaryThis gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21
Gene position43394414 - 43340488  Map Viewer
Gene orientationminus
Gene size53927 bp
Gene sequence
OMIM ID604655