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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MAP3K14 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006468protein phosphorylationIDA
GO:0006955immune responseISS
GO:0007249I-kappaB kinase/NF-kappaB cascadeISS
GO:0031295T cell costimulationTAS
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIMP
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeRCA
GO:0071260cellular response to mechanical stimulusIEP
cellular_component
GO:0005737cytoplasmIEA
GO:0005829cytosolTAS
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityIDA
GO:0004674protein serine/threonine kinase activityIEA
GO:0004704NF-kappaB-inducing kinase activityISS
GO:0004709MAP kinase kinase kinase activityIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA

Protein-protein interaction details for MAP3K14 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CHUKTwo-hybridphysical9244310
CHUKAffinity Capture-Westernphysical9244310
MAP3K8Affinity Capture-Westernphysical10072079
IKBKGAffinity Capture-Westernphysical9927690
CHUKAffinity Capture-Westernphysical10887201
MAP3K14Affinity Capture-Westernphysical10887201
NFKB2Affinity Capture-Westernphysical11239468
CFLARAffinity Capture-Westernphysical11002417
CASP8Affinity Capture-Westernphysical11002417
CASP10Affinity Capture-Westernphysical11002417
CASP3Affinity Capture-Westernphysical11002417
EGFRAffinity Capture-Westernphysical11116146
RIPK1Affinity Capture-Westernphysical11116146
NFKBIAReconstituted Complexphysical9751059
IKBKAPAffinity Capture-Westernphysical9751059
TRAF1Reconstituted Complexphysical11278268
TRAF2Reconstituted Complexphysical11278268
TRAF3Reconstituted Complexphysical11278268
TRAF2Affinity Capture-Westernphysical11278268
CHUKReconstituted Complexphysical11278268
IKBKBReconstituted Complexphysical11278268
TRAF2Two-hybridphysical9020361
TRAF2Two-hybridphysical9020361
TRAF2Affinity Capture-Westernphysical9020361
MAP3K14Biochemical Activityphysical9020361
IKBKBAffinity Capture-Westernphysical9346485
MAP3K7Affinity Capture-Westernphysical10094049
CHUKAffinity Capture-Westernphysical10094049
CHUKBiochemical Activityphysical10094049
TRAF6Affinity Capture-Westernphysical10921914
BIRC2Affinity Capture-Westernphysical18022362
UBCAffinity Capture-Westernphysical18022362
ZFP91Affinity Capture-Westernphysical20682767
ZFP91Reconstituted Complexphysical20682767
UBCAffinity Capture-Westernphysical20682767
ZFP91Affinity Capture-Westernphysical20682767
ZFP91Biochemical Activityphysical20682767
EEF1A1Two-hybridphysical21900206