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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SOCS3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 9021 Official gene symbol SOCS3 Full name suppressor of cytokine signaling 3 Aliases ,ATOD4,CIS3,Cish3,MGC71791,SOCS-3,SSI-3,SSI3, Gene summary This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq] Location Chromosome: 17   Locus: 17q25.3 Gene position 76356158 - 76352859  Map Viewer Gene orientation minus Gene size 3300 bp Gene sequence >SOCS3:complement(41627011..41630310):Length=3300 GGCTCCGACTTGGACTCCCTGCTCCGCTGCTGCCGCTTCGGCCCCGCACGCAGCCAGCCG CCAGCCGCCCGCCCGGCCCAGCTCCCGCCGCGGCCCCTTGCCGCGGTCCCTCTCCTGGTC CCCTCCCGGTTGGTCCGGGGGTGCGCAGGGGGCAGGGCGGGCGCCCAGGGGAAGCTCGAG GGACGCGCGCGCGAAGGCTCCTTTGTGGACTTCACGGCCGCCAACATCTGGGCGCAGCGC GGGCCACCGCTGGCCGTCTCGCCGCCGCGTCGCCTTGGGGACCCGAGGGGGCTCAGCCCC AAGGACGGAGACTTCGATTCGGGACCAGGTAGGAAGGAGGAGCGCGGCGTGGGGAGGGGT CTCGCTCAGTCCCGGGAGCTTTTCCCGGTTTCCCCTCCCCTTCCCGGGTCATTCCCGGCA GGGAGGTGACGAGGTAGGGGCAGAGCGGATGGAAGCCGGAGATCCCAGGTTCCCGGAATA CTCCGGCTGGGGCCTTCGGGCTTCTCCTGTCCCCTCCCTACCCCCGTGCCTCGGGTTTCT CCCTCCGTCCACACCGCCCGGGGCTACTGGACTGAGCGGCGCCCAGGCAGTCCCGGGGGC CCTTCTCCTGCTCCCCACCCGGCCACACTCCTGGAGACCTAACTTCCGCGCGCGAGTTTC CCACGCTGCGCCCTTGCAGTGCGCGCCTGGGAAGGGGCTGCCCGGGGCCACCCTGCCGGC AGGGGCGGGAGCCGTGCGGGCTCCGTGAGGCGCCTGGATCGGAGCGCGGGCCCAGGAGAG GGCCCCCGGGGCAGTGGGTGCCCCAGTCGCTCGGCGAAGGCAGGGGAGCCGGGGCGGGCC GGGCGCGCTGGAGGGTTCCGGGCACTCAACGCGCTCGCGCCTTCCTCTCCGCAGCCCCCC GGGATGCGGTAGCGGCCGCTGTGCGGAGGCCGCGAAGCAGCTGCAGCCGCCGCCGCGCAG ATCCACGCTGGCTCCGTGCGCCATGGTCACCCACAGCAAGTTTCCCGCCGCCGGGATGAG CCGCCCCCTGGACACCAGCCTGCGCCTCAAGACCTTCAGCTCCAAGAGCGAGTACCAGCT GGTGGTGAACGCAGTGCGCAAGCTGCAGGAGAGCGGCTTCTACTGGAGCGCAGTGACCGG CGGCGAGGCGAACCTGCTGCTCAGTGCCGAGCCCGCCGGCACCTTTCTGATCCGCGACAG CTCGGACCAGCGCCACTTCTTCACGCTCAGCGTCAAGACCCAGTCTGGGACCAAGAACCT GCGCATCCAGTGTGAGGGGGGCAGCTTCTCTCTGCAGAGCGATCCCCGGAGCACGCAGCC CGTGCCCCGCTTCGACTGCGTGCTCAAGCTGGTGCACCACTACATGCCGCCCCCTGGAGC CCCCTCCTTCCCCTCGCCACCTACTGAACCCTCCTCCGAGGTGCCCGAGCAGCCGTCTGC CCAGCCACTCCCTGGGAGTCCCCCCAGAAGAGCCTATTACATCTACTCCGGGGGCGAGAA GATCCCCCTGGTGTTGAGCCGGCCCCTCTCCTCCAACGTGGCCACTCTTCAGCATCTCTG TCGGAAGACCGTCAACGGCCACCTGGACTCCTATGAGAAAGTCACCCAGCTGCCGGGGCC CATTCGGGAGTTCCTGGACCAGTACGATGCCCCGCTTTAAGGGGTAAAGGGCGCAAAGGG CATGGGTCGGGAGAGGGGACGCAGGCCCCTCTCCTCCGTGGCACATGGCACAAGCACAAG AAGCCAACCAGGAGAGAGTCCTGTAGCTCTGGGGGGAAAGAGGGCGGACAGGCCCCTCCC TCTGCCCTCTCCCTGCAGAATGTGGCAGGCGGACCTGGAATGTGTTGGAGGGAAGGGGGA GTACCACCTGAGTCTCCAGCTTCTCCGGAGGAGCCAGCTGTCCTGGTGGGACGATAGCAA CCACAAGTGGATTCTCCTTCAATTCCTCAGCTTCCCCTCTGCCTCCAAACAGGGGACACT TCGGGAATGCTGAACTAATGAGAACTGCCAGGGAATCTTCAAACTTTCCAACGGAACTTG TTTGCTCTTTGATTTGGTTTAAACCTGAGCTGGTTGTGGAGCCTGGGAAAGGTGGAAGAG AGAGAGGTCCTGAGGGCCCCAGGGCTGCGGGCTGGCGAAGGAAATGGTCACACCCCCCGC CCACCCCAGGCGAGGATCCTGGTGACATGCTCCTCTCCCTGGCTCCGGGGAGAAGGGCTT GGGGTGACCTGAAGGGAACCATCCTGGTACCCCACATCCTCTCCTCCGGGACAGTCACCG AAAACACAGGTTCCAAAGTCTACCTGGTGCCTGAGAGCCCAGGGCCCTTCCTCCGTTTTA AGGGGGAAGCAACATTTGGAGGGGATGGATGGGCTGGTCAGCTGGTCTCCTTTTCCTACT CATACTATACCTTCCTGTACCTGGGTGGATGGAGCGGGAGGATGGAGGAGACGGGACATC TTTCACCTCAGGCTCCTGGTAGAGAAGACAGGGGATTCTACTCTGTGCCTCCTGACTATG TCTGGCTAAGAGATTCGCCTTAAATGCTCCCTGTCCCATGGAGAGGGACCCAGCATAGGA AAGCCACATACTCAGCCTGGATGGGTGGAGAGGCTGAGGGACTCACTGGAGGGCACCAAG CCAGCCCACAGCCAGGGAAGTGGGGAGGGGGGGCGGAAACCCATGCCTCCCAGCTGAGCA CTGGGAATGTCAGCCCAGTAAGTATTGGCCAGTCAGGCGCCTCGTGGTCAGAGCAGAGCC ACCAGGTCCCACTGCCCCGAGCCCTGCACAGCCCTCCCTCCTGCCTGGGTGGGGGAGGCT GGAGGTCATTGGAGAGGCTGGACTGCTGCCACCCCGGGTGCTCCCGCTCTGCCATAGCAC TGATCAGTGACAATTTACAGGAATGTAGCAGCGATGGAATTACCTGGAACAGTTTTTTGT TTTTGTTTTTGTTTTTGTTTTTGTGGGGGGGGGCAACTAAACAAACACAAAGTATTCTGT GTCAGGTATTGGGCTGGACAGGGCAGTTGTGTGTTGGGGTGGTTTTTTTCTCTATTTTTT TGTTTGTTTCTTGTTTTTTAATAATGTTTACAATCTGCCTCAATCACTCTGTCTTTTATA AAGATTCCACCTCCAGTCCTCTCTCCTCCCCCCTACTCAGGCCCTTGAGGCTATTAGGAG ATGCTTGAAGAACTCAACAAAATCCCAATCCAAGTCAAACTTTGCACATATTTATATTTA TATTCAGAAAAGAAACATTTCAGTAATTTATAATAAAGAGCACTATTTTTTAATGAAAAA OMIM ID 604176