Entrez gene ID | | 9126 |
Official gene symbol | | SMC3 |
Full name | | structural maintenance of chromosomes 3 |
Aliases | | ,BAM,BMH,CDLS3,CSPG6,HCAP,SMC3L1, |
Gene summary | | This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q25 |
Gene position | | 112327449 - 112364392 Map Viewer |
Gene orientation | | plus |
Gene size | | 36944 bp |
Gene sequence |
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OMIM ID | | 606062 |
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