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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SMC3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000087 M phase of mitotic cell cycle TAS GO:0000236 mitotic prometaphase TAS GO:0000278 mitotic cell cycle TAS GO:0006275 regulation of DNA replication IMP GO:0006281 DNA repair IEA GO:0007052 mitotic spindle organization IEP GO:0007062 sister chromatid cohesion IMP GO:0007062 sister chromatid cohesion NAS GO:0007067 mitosis TAS GO:0007091 mitotic metaphase/anaphase transition TAS GO:0007126 meiosis IDA GO:0007165 signal transduction IDA GO:0009294 DNA mediated transformation TAS GO:0032876 negative regulation of DNA endoreduplication IMP GO:0051301 cell division IEA cellular_component GO:0000775 chromosome, centromeric region IEA GO:0000785 chromatin IDA GO:0000800 lateral element IEA GO:0000922 spindle pole IDA GO:0005604 basement membrane IEA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005694 chromosome IEA GO:0005737 cytoplasm IDA GO:0008278 cohesin complex NAS GO:0016363 nuclear matrix IDA GO:0030893 meiotic cohesin complex IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003777 microtubule motor activity NAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0045502 dynein binding IDA GO:0046982 protein heterodimerization activity IPI

Protein-protein interaction details for SMC3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CASP4 Affinity Capture-MS physical 17353931 NEK6 Affinity Capture-MS physical 17353931 CDK4 Affinity Capture-MS physical 17353931 MAGED1 Affinity Capture-MS physical 17353931 SMC1A Affinity Capture-Western physical 11877376 REC8 Affinity Capture-Western physical 12759374 SMC1A Affinity Capture-Western physical 12759374 SMC1A Affinity Capture-Western physical 12759374 SYCP3 Affinity Capture-Western physical 12759374 REC8 Affinity Capture-Western physical 12759374 SMARCA5 Co-purification physical 12198550 HDAC2 Co-purification physical 12198550 SMC1A Affinity Capture-Western physical 9789013 SMC1A Affinity Capture-Western physical 11590136 NUMA1 Affinity Capture-Western physical 11590136 TUBB Affinity Capture-Western physical 11590136 STAG1 Co-purification physical 11076961 MXI1 Two-hybrid physical 9528857 MXD3 Two-hybrid physical 9528857 MXD4 Two-hybrid physical 9528857 MXD1 Two-hybrid physical 9528857 MXD3 Reconstituted Complex physical 9528857 MXD4 Reconstituted Complex physical 9528857 MXI1 Reconstituted Complex physical 9528857 MXD1 Reconstituted Complex physical 9528857 KIFAP3 Two-hybrid physical 9506951 KIFAP3 Reconstituted Complex physical 9506951 STAG3 Affinity Capture-Western physical 11483963 RAE1 Affinity Capture-Western physical 18832153 USP13 Affinity Capture-MS physical 19615732 ATM Affinity Capture-Western physical 17478428 PMS1 Affinity Capture-Western physical 17148452 AIRE Affinity Capture-MS physical 20085707 BECN1 Affinity Capture-MS physical 20562859 CAMKK2 Affinity Capture-MS physical 20562859 APC Two-hybrid physical 20936779 WFDC5 Affinity Capture-Western physical 19906707 PDS5A Affinity Capture-Western physical 19906707 CDCA5 Reconstituted Complex physical 15837422 CDCA5 Affinity Capture-Western physical 15837422 FEZ1 Two-hybrid physical 16484223 FEZ1 Reconstituted Complex physical 16484223 FEZ2 Two-hybrid physical 16484223 SRRM1 Co-fractionation physical 16159877 SRRM1 Affinity Capture-MS physical 16159877 RPGR Affinity Capture-Western physical 16043481 RPGR Reconstituted Complex physical 16043481 RPGR Reconstituted Complex physical 16043481 PAXIP1 Affinity Capture-MS physical 17925232 TERF2 Affinity Capture-MS physical 20811636 SSU72 Affinity Capture-Western physical 20818333 RAD21 Affinity Capture-Western physical 20818333 STAG1 Affinity Capture-MS physical 17113138 STAG2 Affinity Capture-MS physical 17113138 RAD21 Affinity Capture-MS physical 17113138 SMC1A Affinity Capture-MS physical 17113138 STAG1 Affinity Capture-MS physical 17113138 STAG2 Affinity Capture-MS physical 17113138 PDS5A Affinity Capture-MS physical 17113138 PDS5B Affinity Capture-MS physical 17113138 WFDC5 Affinity Capture-MS physical 17113138 PDS5A Affinity Capture-MS physical 17113138 PDS5B Affinity Capture-MS physical 17113138 WFDC5 Affinity Capture-MS physical 17113138 WFDC5 Affinity Capture-Western physical 17113138 WFDC5 Affinity Capture-Western physical 17113138 STAG1 Affinity Capture-Western physical 17113138 STAG2 Affinity Capture-Western physical 17113138 RAD21 Affinity Capture-Western physical 17113138 RAD21 Co-fractionation physical 17113138 PDS5A Affinity Capture-Western physical 17113138 STAG1 Reconstituted Complex physical 17112726 HDAC5 Affinity Capture-MS physical 21081666 SMC1A Affinity Capture-MS physical 17349791 RAD21 Affinity Capture-MS physical 17349791 STAG1 Affinity Capture-MS physical 17349791 STAG2 Affinity Capture-MS physical 17349791 PDS5A Affinity Capture-MS physical 17349791 PDS5B Affinity Capture-MS physical 17349791 WAPAL Affinity Capture-MS physical 17349791 CDCA5 Affinity Capture-MS physical 17349791 SMC1A Affinity Capture-Western physical 17349791 RAD21 Affinity Capture-Western physical 17349791 PDS5B Affinity Capture-Western physical 17349791 CDCA5 Affinity Capture-Western physical 17349791 WAPAL Affinity Capture-MS physical 20360068 DISC1 Two-hybrid physical 17043677 Cep63 Two-hybrid physical 17043677 TRAF3IP1 Two-hybrid physical 17043677 PDS5A Affinity Capture-Western physical 15855230 PDS5B Affinity Capture-Western physical 15855230 RAD21 Affinity Capture-Western physical 15855230 STAG1 Affinity Capture-Western physical 15855230 STAG2 Affinity Capture-Western physical 15855230 PDS5A Affinity Capture-Western physical 15855230 PDS5B Affinity Capture-Western physical 15855230 STAG1 Affinity Capture-Western physical 17962804 STAG2 Affinity Capture-Western physical 17962804