Entrez gene ID | | 91662 |
Official gene symbol | | NLRP12 |
Full name | | NLR family, pyrin domain containing 12 |
Aliases | | ,CLR19.3,FCAS2,NALP12,PAN6,PYPAF7,RNO,RNO2, |
Gene summary | | This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.42 |
Gene position | | 54327648 - 54296838 Map Viewer |
Gene orientation | | minus |
Gene size | | 30811 bp |
Gene sequence |
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OMIM ID | | 609648 |
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