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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NLRP12 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006919activation of caspase activityNAS
GO:0007165signal transductionNAS
GO:0008588release of cytoplasmic sequestered NF-kappaBIDA
GO:0009968negative regulation of signal transductionIDA
GO:0031953negative regulation of protein autophosphorylationIDA
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB cascadeIDA
GO:0045381regulation of interleukin-18 biosynthetic processNAS
GO:0045409negative regulation of interleukin-6 biosynthetic processIDA
GO:0045751negative regulation of Toll signaling pathwayIDA
GO:0050710negative regulation of cytokine secretionIDA
GO:0050711negative regulation of interleukin-1 secretionIDA
GO:0050718positive regulation of interleukin-1 beta secretionNAS
GO:0050729positive regulation of inflammatory responseNAS
cellular_component
GO:0005737cytoplasmIDA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0008656caspase activator activityNAS

Protein-protein interaction details for NLRP12 (Homo sapiens)
(Information is obtained from BioGRID)
Not available