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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for COPS5 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000338 protein deneddylation IMP GO:0006366 transcription from RNA polymerase II promoter TAS GO:0006412 translation TAS GO:0006413 translational initiation TAS GO:0010388 cullin deneddylation IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0046328 regulation of JNK cascade IDA GO:0051726 regulation of cell cycle IEA cellular_component GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IEA GO:0005852 eukaryotic translation initiation factor 3 complex TAS GO:0008180 signalosome IDA GO:0008180 signalosome IEA molecular_function GO:0003713 transcription coactivator activity TAS GO:0003743 translation initiation factor activity TAS GO:0005515 protein binding IPI GO:0008233 peptidase activity IEA GO:0008237 metallopeptidase activity IMP GO:0046872 metal ion binding IEA

Protein-protein interaction details for COPS5 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HAND2 Two-hybrid physical 11812799 S100A7 Two-hybrid physical 12702588 S100A7 Affinity Capture-Western physical 12702588 BCL3 Two-hybrid physical 10362352 BCL3 Reconstituted Complex physical 10362352 BCL3 Affinity Capture-Western physical 10362352 UCHL1 Two-hybrid physical 12082530 UCHL1 Affinity Capture-Western physical 12082530 CDKN1B Affinity Capture-Western physical 12082530 COPS8 Co-purification physical 9707402 JUN Two-hybrid physical 8837781 JUN Affinity Capture-Western physical 8837781 JUN Co-localization physical 8837781 JUND Co-localization physical 8837781 MIF Affinity Capture-Western physical 11089976 MIF Reconstituted Complex physical 11089976 SMAD4 Two-hybrid physical 11818334 SMAD4 Reconstituted Complex physical 11818334 SMAD4 Affinity Capture-Western physical 11818334 SMAD4 Affinity Capture-Western physical 11818334 GFER Two-hybrid physical 11709497 GFER Reconstituted Complex physical 11709497 GFER Affinity Capture-Western physical 11709497 SAP130 Affinity Capture-Western physical 18173839 CPSF1 Affinity Capture-Western physical 18173839 TP53 Affinity Capture-Western physical 17879958 TP53 Reconstituted Complex physical 17879958 TP53 Affinity Capture-Western physical 17879958 MDM2 Affinity Capture-Western physical 17879958 MDM2 Reconstituted Complex physical 17879958 MAPRE1 Reconstituted Complex physical 17350042 ERCC8 Affinity Capture-MS physical 19615732 DDB2 Affinity Capture-MS physical 19615732 GPS1 Affinity Capture-MS physical 19615732 NEDD8 Affinity Capture-MS physical 19615732 SKP2 Affinity Capture-MS physical 19615732 UCHL3 Affinity Capture-MS physical 19615732 CUL4B Affinity Capture-MS physical 19615732 CUL4A Affinity Capture-MS physical 19615732 CUL3 Affinity Capture-MS physical 19615732 CUL2 Affinity Capture-MS physical 19615732 CUL1 Affinity Capture-MS physical 19615732 COPS3 Affinity Capture-MS physical 19615732 COPS2 Affinity Capture-MS physical 19615732 LRRC14 Affinity Capture-MS physical 19615732 VprBP Affinity Capture-MS physical 19615732 COPS8 Affinity Capture-MS physical 19615732 COPS6 Affinity Capture-MS physical 19615732 COPS6 Affinity Capture-MS physical 19615732 KLHL18 Affinity Capture-MS physical 19615732 DCAF4 Affinity Capture-MS physical 19615732 FBXO22 Affinity Capture-MS physical 19615732 COPS7A Affinity Capture-MS physical 19615732 COPS4 Affinity Capture-MS physical 19615732 KLHL24 Affinity Capture-MS physical 19615732 BTBD2 Affinity Capture-MS physical 19615732 KLHL9 Affinity Capture-MS physical 19615732 COPS7B Affinity Capture-MS physical 19615732 FBXO11 Affinity Capture-MS physical 19615732 KLHL15 Affinity Capture-MS physical 19615732 DCAF11 Affinity Capture-MS physical 19615732 KLHL22 Affinity Capture-MS physical 19615732 KLHL13 Affinity Capture-MS physical 19615732 FBXO17 Affinity Capture-MS physical 19615732 PPIL5 Affinity Capture-MS physical 19615732 KLHL13 Affinity Capture-MS physical 19615732 PTGS2 Co-fractionation physical 17429597 PTGS2 Affinity Capture-Western physical 17429597 COPS7A Affinity Capture-Western physical 17429597 GFER Two-hybrid physical 14500725 GFER Affinity Capture-Western physical 14500725 DDB1 Affinity Capture-MS physical 16964240 CUL4A Affinity Capture-MS physical 16964240 CDKN1B Reconstituted Complex physical 16951171 CDKN1B Reconstituted Complex physical 16951171 CDKN1B Affinity Capture-Western physical 16951171 DDB1 Affinity Capture-MS physical 16949367 TRAF2 Affinity Capture-Western physical 16936264 TRAF2 Affinity Capture-Western physical 16936264 TP53 Affinity Capture-Western physical 16936264 TOR1AIP2 Affinity Capture-MS physical 19615732 MAP3K3 Two-hybrid physical 20936779 MAP3K11 Two-hybrid physical 20936779 MAP2K2 Two-hybrid physical 20936779 MAP3K7 Two-hybrid physical 20936779 MAP4K3 Two-hybrid physical 20936779 MAP4K5 Two-hybrid physical 20936779 MEF2D Two-hybrid physical 20936779 SREBF2 Two-hybrid physical 20936779 YWHAZ Two-hybrid physical 20936779 MAX Two-hybrid physical 20936779 MEF2C Two-hybrid physical 20936779 YWHAG Two-hybrid physical 20936779 WNK1 Two-hybrid physical 20936779 COPS3 Affinity Capture-MS physical 16036220 CUL1 Affinity Capture-Western physical 16036220 CUL1 Affinity Capture-Western physical 16036220 BRE Affinity Capture-Western physical 19214193 BRCC3 Affinity Capture-Western physical 19214193 VCP Affinity Capture-Western physical 19826004 VCP Affinity Capture-Western physical 19826004 VCP Reconstituted Complex physical 19826004 VCP Co-fractionation physical 19826004 EDNRA Two-hybrid physical 20034471 EDNRA Reconstituted Complex physical 20034471 EDNRA Affinity Capture-Western physical 20034471 EDNRA Affinity Capture-Western physical 20034471 EDNRB Affinity Capture-Western physical 20034471 CSN1S1 Affinity Capture-MS physical 18850735 COPS2 Affinity Capture-MS physical 18850735 COPS3 Affinity Capture-MS physical 18850735 COPS4 Affinity Capture-MS physical 18850735 COPS6 Affinity Capture-MS physical 18850735 COPS7A Affinity Capture-MS physical 18850735 COPS7B Affinity Capture-MS physical 18850735 COPS8 Affinity Capture-MS physical 18850735 COPS3 Affinity Capture-MS physical 20399188 IKBKB Two-hybrid physical 19656241 IKBKB Affinity Capture-Western physical 19656241 IKBKB FRET physical 19656241 COPS7A Affinity Capture-Western physical 19656241 IKBKB Biochemical Activity physical 19656241 CHUK Biochemical Activity physical 19656241 UBC Affinity Capture-Western physical 19656241 UBC Affinity Capture-Western physical 19656241 ABCA1 Affinity Capture-Western physical 19268428 ABCA1 Affinity Capture-Western physical 19268428 PPARG Two-hybrid physical 15604093 RORA Two-hybrid physical 15604093 HNF4A Two-hybrid physical 15604093 HNF4G Two-hybrid physical 15604093 NR4A2 Two-hybrid physical 15604093 NR4A3 Two-hybrid physical 15604093 NR5A2 Two-hybrid physical 15604093 MALT1 Affinity Capture-Western physical 19444310 CARD11 Affinity Capture-Western physical 19444310 CARD11 Affinity Capture-Western physical 19444310 GNB2L1 Two-hybrid physical 18624398 MAP2K2 Two-hybrid physical 18624398 ATRN Two-hybrid physical 18624398 LOC284014 Two-hybrid physical 18624398 C12orf10 Two-hybrid physical 18624398 PLAC8 Two-hybrid physical 18624398 PPOX Two-hybrid physical 18624398 SHISA5 Two-hybrid physical 18624398 USP14 Two-hybrid physical 18624398 VTN Two-hybrid physical 18624398 MAPK14 Two-hybrid physical 18624398 IRF8 Affinity Capture-MS physical 21903422 UBC Co-purification physical 17623298 CUL1 Affinity Capture-Western physical 21249194