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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CRK (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000186 activation of MAPKK activity TAS GO:0006357 regulation of transcription from RNA polymerase II promoter TAS GO:0007596 blood coagulation TAS GO:0008286 insulin receptor signaling pathway TAS GO:0032319 regulation of Rho GTPase activity IDA GO:0032956 regulation of actin cytoskeleton organization IDA GO:0035020 regulation of Rac protein signal transduction IEA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0048013 ephrin receptor signaling pathway IDA cellular_component GO:0005634 nucleus TAS GO:0005737 cytoplasm IC GO:0005768 endosome TAS GO:0005829 cytosol TAS GO:0005886 plasma membrane IEA molecular_function GO:0005070 SH3/SH2 adaptor activity IEA GO:0005515 protein binding IPI GO:0042169 SH2 domain binding IPI GO:0045309 protein phosphorylated amino acid binding IEA GO:0046875 ephrin receptor binding IPI

Protein-protein interaction details for CRK (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PLSCR1 Two-hybrid physical 16189514 DPPA4 Two-hybrid physical 16189514 BUB1 Two-hybrid physical 16189514 PSMC6 Two-hybrid physical 16189514 EGFR Affinity Capture-MS physical 16729043 ERBB4 Affinity Capture-MS physical 16729043 BCAR1 Affinity Capture-Western physical 15492270 BCAR1 Affinity Capture-Western physical 14657239 SRCIN1 Affinity Capture-Western physical 14657239 ARHGAP32 Reconstituted Complex physical 12819203 ARHGAP32 Affinity Capture-Western physical 12819203 DOCK1 Reconstituted Complex physical 12615911 BCAR1 Affinity Capture-Western physical 12615911 DOCK1 Affinity Capture-Western physical 12615911 SRC Affinity Capture-Western physical 12615911 BCAR1 Affinity Capture-Western physical 12615911 DOCK1 Affinity Capture-Western physical 12615911 PTK2 Affinity Capture-Western physical 12615911 MAP4K1 Reconstituted Complex physical 9788432 EPHA3 Affinity Capture-Western physical 11870224 SH3KBP1 Affinity Capture-Western physical 11071869 SH3KBP1 Affinity Capture-Western physical 11071869 SOCS1 Reconstituted Complex physical 10022833 DOCK1 Affinity Capture-Western physical 10559471 DOCK1 Co-fractionation physical 8657152 DOCK1 Affinity Capture-Western physical 8657152 IRS4 Affinity Capture-Western physical 11316748 MAPK8 Affinity Capture-Western physical 11432831 MAPK8 Reconstituted Complex physical 11432831 KHDRBS1 Reconstituted Complex physical 1545818 DOCK1 Affinity Capture-Western physical 11369773 BCAR1 Affinity Capture-Western physical 11369773 BCAR1 Affinity Capture-Western physical 9920935 ASAP1 Reconstituted Complex physical 9819391 PDGFRA Affinity Capture-Western physical 9546424 EGFR Biochemical Activity physical 9642287 EGFR Affinity Capture-Western physical 9642287 AVIL Reconstituted Complex physical 11287316 GRB2 Reconstituted Complex physical 10970810 ARHGAP17 Reconstituted Complex physical 11431473 DOCK1 Reconstituted Complex physical 8662907 GRB2 Far Western physical 8662907 RET Reconstituted Complex physical 9393871 BCAR1 Reconstituted Complex physical 10085298 PTK2 Reconstituted Complex physical 10085298 PXN Reconstituted Complex physical 10085298 PDGFRA Affinity Capture-Western physical 10733900 PDGFRB Affinity Capture-Western physical 10733900 PDGFRA Reconstituted Complex physical 10733900 PDGFRB Reconstituted Complex physical 10733900 NEDD9 Affinity Capture-Western physical 8879209 NCK1 Reconstituted Complex physical 8879209 IRS4 Reconstituted Complex physical 9614078 EPHB3 Reconstituted Complex physical 9674711 ARHGAP32 Affinity Capture-Western physical 12454018 FRS2 Reconstituted Complex physical 10092678 MAP4K5 Affinity Capture-Western physical 10648385 EPHB2 Reconstituted Complex physical 10644995 RAPGEF1 Affinity Capture-Western physical 7512734 RAPGEF1 Affinity Capture-Western physical 7512734 RAPGEF1 Far Western physical 7512734 SH3BP1 Reconstituted Complex physical 1379745 SOS1 Reconstituted Complex physical 8810325 GRB2 Affinity Capture-Western physical 8810325 GRB2 Affinity Capture-Western physical 8810325 SOS1 Affinity Capture-Western physical 8810325 SOS1 Affinity Capture-Western physical 8810325 PXN Affinity Capture-Western physical 12198159 XPO1 Two-hybrid physical 11839808 WEE1 Affinity Capture-Western physical 11839808 NEDD9 Affinity Capture-Western physical 9497377 NEDD9 Affinity Capture-Western physical 9497377 NEDD9 Reconstituted Complex physical 9497377 SHB Affinity Capture-Western physical 10964504 ZAP70 Reconstituted Complex physical 10419455 EPS15 Far Western physical 7797522 EPS15 Reconstituted Complex physical 7797522 BCAR1 Affinity Capture-Western physical 9581808 CBL Affinity Capture-Western physical 9461587 KCNIP3 Affinity Capture-Western physical 10854253 CBL Affinity Capture-Western physical 9178909 PTPN1 Reconstituted Complex physical 8940134 BCAR1 Affinity Capture-Western physical 10329689 MAP4K1 Reconstituted Complex physical 9891069 MAP4K1 Affinity Capture-Western physical 9891069 CBLC Reconstituted Complex physical 10362357 MICAL1 Reconstituted Complex physical 11827972 MAP4K1 Affinity Capture-Western physical 11279207 SYN1 Affinity Capture-Western physical 10899172 BCAR1 Affinity Capture-Western physical 10753828 BCAR1 Affinity Capture-Western physical 16267043