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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CYP3A4 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006629 lipid metabolic process TAS GO:0006706 steroid catabolic process IMP GO:0006805 xenobiotic metabolic process TAS GO:0008202 steroid metabolic process IMP GO:0008209 androgen metabolic process TAS GO:0009822 alkaloid catabolic process IDA GO:0016098 monoterpenoid metabolic process IDA GO:0017144 drug metabolic process IDA GO:0042359 vitamin D metabolic process IC GO:0042737 drug catabolic process IDA GO:0042737 drug catabolic process IMP GO:0042738 exogenous drug catabolic process IDA GO:0046483 heterocycle metabolic process IDA GO:0055114 oxidation-reduction process IDA GO:0055114 oxidation-reduction process IEA GO:0070989 oxidative demethylation IDA cellular_component GO:0005737 cytoplasm IDA GO:0005783 endoplasmic reticulum IEA GO:0005789 endoplasmic reticulum membrane TAS GO:0005792 microsome IDA GO:0009986 cell surface IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA molecular_function GO:0004497 monooxygenase activity IDA GO:0004497 monooxygenase activity IEA GO:0004497 monooxygenase activity ISS GO:0005496 steroid binding IDA GO:0005506 iron ion binding IDA GO:0008395 steroid hydroxylase activity IMP GO:0009055 electron carrier activity IEA GO:0016491 oxidoreductase activity IDA GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA GO:0019825 oxygen binding TAS GO:0019899 enzyme binding IPI GO:0020037 heme binding IEA GO:0030343 vitamin D3 25-hydroxylase activity IDA GO:0033780 taurochenodeoxycholate 6alpha-hydroxylase activity IEA GO:0034875 caffeine oxidase activity IDA GO:0046872 metal ion binding IEA GO:0047638 albendazole monooxygenase activity IEA GO:0050591 quinine 3-monooxygenase activity IEA GO:0050649 testosterone 6-beta-hydroxylase activity IMP GO:0070576 vitamin D 24-hydroxylase activity IDA

Protein-protein interaction details for CYP3A4 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID AMFR Biochemical Activity physical 19103148 STUB1 Biochemical Activity physical 19103148 AMFR Biochemical Activity physical 22101235 STUB1 Biochemical Activity physical 22101235 AMFR Biochemical Activity physical 21209460