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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DAXX (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000281 cytokinesis after mitosis IEA GO:0006355 regulation of transcription, DNA-dependent IDA GO:0006915 apoptosis TAS GO:0006917 induction of apoptosis ISS GO:0007257 activation of JUN kinase activity TAS GO:0008625 induction of apoptosis via death domain receptors TAS GO:0030521 androgen receptor signaling pathway IDA GO:0031396 regulation of protein ubiquitination IDA GO:0044419 interspecies interaction between organisms IEA GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045892 negative regulation of transcription, DNA-dependent IEA cellular_component GO:0000775 chromosome, centromeric region IEA GO:0000792 heterochromatin IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005634 nucleus IMP GO:0005654 nucleoplasm IEA GO:0005694 chromosome IEA GO:0005730 nucleolus IEA GO:0005737 cytoplasm IEA GO:0005737 cytoplasm TAS GO:0005829 cytosol ISS GO:0005938 cell cortex IEA GO:0016605 PML body IDA GO:0016605 PML body IEA GO:0016605 PML body TAS GO:0043005 neuron projection IEA GO:0044297 cell body IEA molecular_function GO:0002039 p53 binding IPI GO:0005057 receptor signaling protein activity TAS GO:0005515 protein binding IPI GO:0008134 transcription factor binding IDA GO:0019899 enzyme binding IPI GO:0031072 heat shock protein binding TAS GO:0031625 ubiquitin protein ligase binding IPI GO:0042803 protein homodimerization activity IDA GO:0047485 protein N-terminus binding IPI GO:0050681 androgen receptor binding IPI

Protein-protein interaction details for DAXX (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SLC2A4 Two-hybrid physical 11842083 ETS1 Two-hybrid physical 10698492 MCRS1 Two-hybrid physical 11948183 AR Two-hybrid physical 15572661 AR Reconstituted Complex physical 15572661 AR Affinity Capture-Western physical 15572661 PML Two-hybrid physical 10525530 FANCA Two-hybrid physical 14499622 HIPK2 Reconstituted Complex physical 14678985 HIPK2 Affinity Capture-Western physical 14678985 DAPK3 Affinity Capture-Western physical 12917339 DAPK3 Affinity Capture-Western physical 12917339 NR3C1 Affinity Capture-Western physical 12595526 NR3C1 Reconstituted Complex physical 12595526 NR3C1 Two-hybrid physical 12595526 SUMO1 Two-hybrid physical 11948183 MCRS1 Reconstituted Complex physical 11948183 MCRS1 Affinity Capture-Western physical 11948183 MCRS1 Affinity Capture-Western physical 11948183 PML Two-hybrid physical 10669754 PML Affinity Capture-Western physical 10669754 HDAC1 Far Western physical 10669754 HDAC2 Far Western physical 10669754 HDAC3 Far Western physical 10669754 HDAC1 Reconstituted Complex physical 10669754 HDAC1 Affinity Capture-Western physical 10669754 PML Co-localization physical 10669754 PAX5 Two-hybrid physical 11799127 PAX5 Reconstituted Complex physical 11799127 CENPC1 Two-hybrid physical 9645950 SLC2A4 Reconstituted Complex physical 11842083 SLC2A4 Affinity Capture-Western physical 11842083 SLC2A4 Affinity Capture-Western physical 11842083 SUMO1 Two-hybrid physical 11112409 SUMO1 Reconstituted Complex physical 11112409 SUMO1 Affinity Capture-Western physical 11112409 UBE2I Two-hybrid physical 11112409 PAX3 Affinity Capture-Western physical 10393185 PML Two-hybrid physical 11244500 UBE2I Biochemical Activity physical 18691969 ETS1 Reconstituted Complex physical 10698492 PML Affinity Capture-Western physical 10684855 TGFB2 Reconstituted Complex physical 11483955 FAS Reconstituted Complex physical 11483955 MAP3K5 Affinity Capture-Western physical 9743501 MAP3K5 Affinity Capture-Western physical 9743501 HIPK1 Affinity Capture-Western physical 12529400 MX1 Two-hybrid physical 11716541 CDKN2A Reconstituted Complex physical 18583933 CDKN2A Affinity Capture-Western physical 18583933 CDKN2A Affinity Capture-Western physical 18583933 MDM2 Affinity Capture-Western physical 18583933 MDM2 Affinity Capture-Western physical 18583933 UBC Affinity Capture-Western physical 18583933 SUMO1 Affinity Capture-Western physical 18583933 RASSF1 Affinity Capture-Western physical 18566590 RASSF1 Reconstituted Complex physical 18566590 PLAGL1 Two-hybrid physical 20097304 PLAGL1 Reconstituted Complex physical 20097304 UBC Affinity Capture-Western physical 16810318 RASSF1 Affinity Capture-Western physical 16810318 RASSF1 Affinity Capture-Western physical 16810318 TCF3 Reconstituted Complex physical 19308989 AXIN1 Two-hybrid physical 17210684 AXIN1 Affinity Capture-Western physical 17210684 AXIN1 Affinity Capture-Western physical 17210684 MYH11 Two-hybrid physical 20936779 UBC Two-hybrid physical 20936779 HIST1H4A Affinity Capture-MS physical 19862764 HIST1H4A Affinity Capture-Western physical 19862764 TCF4 Two-hybrid physical 20211142 RELB Affinity Capture-Western physical 16982744 ETS1 Affinity Capture-Western physical 16861237 ETS1 Affinity Capture-Western physical 16861237 HABP4 Two-hybrid physical 16455055 SUMO2 Affinity Capture-MS physical 19394292 CREBBP Two-hybrid physical 16287980 CREBBP Affinity Capture-Western physical 16287980 ATRX Affinity Capture-Western physical 12953102 ATRX Affinity Capture-MS physical 12953102 ATRX Co-purification physical 12953102 ATRX Affinity Capture-MS physical 12953102 ATRX Affinity Capture-Western physical 12953102 DEK Affinity Capture-Western physical 12140263 HDAC2 Affinity Capture-Western physical 12140263 HIST1H4A Affinity Capture-Western physical 12140263 SMAD4 Two-hybrid physical 15637079 SMAD4 Affinity Capture-Western physical 15637079 SMAD4 Affinity Capture-Western physical 15637079 ATRX Affinity Capture-Western physical 15252119 ATRX Reconstituted Complex physical 14990586 ATRX Affinity Capture-Western physical 14990586 ATRX Affinity Capture-Western physical 14990586 ATRX Co-fractionation physical 14990586 H3F3A Affinity Capture-Western physical 20651253 H3F3A Reconstituted Complex physical 20651253 SUMO1 Affinity Capture-Western physical 19465479 STUB1 Affinity Capture-Western physical 19465479 HIPK2 Affinity Capture-Western physical 19465479 UBC Reconstituted Complex physical 19465479 STUB1 Reconstituted Complex physical 19465479 H3F3A Affinity Capture-MS physical 20504901 H3F3A Affinity Capture-Western physical 20504901 H3F3A Reconstituted Complex physical 20504901 MDM2 Affinity Capture-Western physical 16845383 MDM2 Reconstituted Complex physical 16845383 USP7 Reconstituted Complex physical 16845383 USP7 Affinity Capture-Western physical 16845383 MDM2 Affinity Capture-Western physical 16845383 TP53 Affinity Capture-Western physical 16845383 USP7 Co-localization physical 16845383 USP7 Affinity Capture-Western physical 16845383 MAP3K5 Affinity Capture-Western physical 19789334 UBC Affinity Capture-Western physical 19789334 UBC Affinity Capture-Western physical 19789334 RPL13 Two-hybrid physical 21900206 CA12 Two-hybrid physical 21900206 DMAP1 Affinity Capture-Western physical 14978102 DMAP1 Affinity Capture-Western physical 14978102 DNMT1 Affinity Capture-Western physical 14978102 DNMT1 Affinity Capture-Western physical 14978102 PML Co-localization physical 21779164 MDM2 Affinity Capture-Western physical 18566590 USP7 Affinity Capture-Western physical 18566590 SUMO1 Reconstituted Complex physical 20972456 PML Biochemical Activity physical 20972456 SUMO1 Co-crystal Structure physical 21383010 SUMO2 Co-crystal Structure physical 21383010 SUMO1 Reconstituted Complex physical 21383010 SUMO2 Reconstituted Complex physical 21383010