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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DUSP6 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000188inactivation of MAPK activityIDA
GO:0001933negative regulation of protein phosphorylationIEA
GO:0002224toll-like receptor signaling pathwayTAS
GO:0002755MyD88-dependent toll-like receptor signaling pathwayTAS
GO:0002756MyD88-independent toll-like receptor signaling pathwayTAS
GO:0006470protein dephosphorylationIEA
GO:0008063Toll signaling pathwayTAS
GO:0009953dorsal/ventral pattern formationIBA
GO:0014070response to organic cyclic compoundIEA
GO:0030154cell differentiationIEA
GO:0034130toll-like receptor 1 signaling pathwayTAS
GO:0034134toll-like receptor 2 signaling pathwayTAS
GO:0034138toll-like receptor 3 signaling pathwayTAS
GO:0034142toll-like receptor 4 signaling pathwayTAS
GO:0035335peptidyl-tyrosine dephosphorylationIDA
GO:0040036regulation of fibroblast growth factor receptor signaling pathwayIBA
GO:0042493response to drugIEA
GO:0042663regulation of endodermal cell fate specificationIBA
GO:0043065positive regulation of apoptosisIDA
GO:0045087innate immune responseTAS
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0051403stress-activated MAPK cascadeTAS
GO:0051409response to nitrosative stressIEP
GO:0060420regulation of heart growthIBA
GO:0070373negative regulation of ERK1 and ERK2 cascadeIMP
GO:0070848response to growth factor stimulusIEA
cellular_component
GO:0005654nucleoplasmTAS
GO:0005737cytoplasmIDA
GO:0005829cytosolIBA
molecular_function
GO:0004725protein tyrosine phosphatase activityIEA
GO:0016787hydrolase activityIEA
GO:0016791phosphatase activityIEA
GO:0017017MAP kinase tyrosine/serine/threonine phosphatase activityIDA
GO:0017017MAP kinase tyrosine/serine/threonine phosphatase activityIEA

Protein-protein interaction details for DUSP6 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
MDFITwo-hybridphysical16189514
TEX11Two-hybridphysical16189514
MAPK14Affinity Capture-Westernphysical11359773
MAPK3Reconstituted Complexphysical9535927
MAPK1Reconstituted Complexphysical9535927
MAPK3Affinity Capture-Westernphysical9535927