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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for EIF4E (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000082 G1/S transition of mitotic cell cycle IMP GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay TAS GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening TAS GO:0006406 mRNA export from nucleus TAS GO:0006412 translation TAS GO:0006413 translational initiation ISS GO:0006413 translational initiation TAS GO:0006417 regulation of translation IEA GO:0008286 insulin receptor signaling pathway TAS GO:0010467 gene expression TAS GO:0016070 RNA metabolic process TAS GO:0016071 mRNA metabolic process TAS GO:0044267 cellular protein metabolic process TAS GO:0044419 interspecies interaction between organisms IEA GO:0045931 positive regulation of mitotic cell cycle IMP cellular_component GO:0000932 cytoplasmic mRNA processing body IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005845 mRNA cap binding complex IDA GO:0005845 mRNA cap binding complex IEA GO:0016281 eukaryotic translation initiation factor 4F complex TAS GO:0016442 RNA-induced silencing complex IDA molecular_function GO:0000339 RNA cap binding TAS GO:0003723 RNA binding IEA GO:0003743 translation initiation factor activity IEA GO:0003743 translation initiation factor activity ISS GO:0005515 protein binding IPI

Protein-protein interaction details for EIF4E (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EIF4EBP1 Two-hybrid physical 16189514 EIF4EBP1 Affinity Capture-MS physical 17353931 EIF4A2 Affinity Capture-MS physical 17353931 EIF4A1 Affinity Capture-MS physical 17353931 EIF4ENIF1 Far Western physical 10856257 EIF4ENIF1 Affinity Capture-Western physical 10856257 PML Reconstituted Complex physical 11500381 EIF4G2 Affinity Capture-Western physical 9418880 EIF4G2 Far Western physical 9418880 EIF4G1 Affinity Capture-Western physical 10600798 EIF4G1 Far Western physical 7651417 EIF4EBP1 Reconstituted Complex physical 7651417 EIF4EBP2 Reconstituted Complex physical 7651417 EIF4A1 Affinity Capture-Western physical 16648488 EIF4E Affinity Capture-Western physical 16648488 EIF4EBP1 Affinity Capture-Western physical 16242075 EIF4EBP1 Affinity Capture-Western physical 16824195 EIF4EBP1 Reconstituted Complex physical 10405182 EIF4G1 Affinity Capture-Western physical 16648488 EIF4G1 Affinity Capture-Western physical 16541103 EIF3B Affinity Capture-Western physical 16541103 EIF4EBP1 Co-purification physical 12071973 EIF4EBP1 Affinity Capture-Western physical 10753870 EIF4EBP1 Affinity Capture-Western physical 10698949 EIF4EBP1 Reconstituted Complex physical 10364159 EIF4EBP1 Affinity Capture-Western physical 16648488 EIF4G1 Affinity Capture-Western physical 10753870 EIF4G1 Affinity Capture-Western physical 16648488 EIF4G1 Affinity Capture-Western physical 16541103 EIF4EBP1 Reconstituted Complex physical 11605658 MKNK1 Affinity Capture-Western physical 9878069 EIF4EBP2 Reconstituted Complex physical 7935836 EIF4EBP3 Affinity Capture-Western physical 12482586 EIF4EBP3 Affinity Capture-Western physical 9593750 EIF4EBP1 Affinity Capture-Western physical 18957614 EIF3F Affinity Capture-MS physical 19615732 EIF4G1 Affinity Capture-Western physical 16720573 UBC Affinity Capture-Western physical 16720573 STUB1 Affinity Capture-Western physical 16720573 DCC Co-fractionation physical 20434207 DCC Affinity Capture-Western physical 20434207 HSPB2 Affinity Capture-Western physical 20101233 UBC Affinity Capture-Western physical 20101233 RPS6KA5 Biochemical Activity physical 9873047