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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ERBB3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0003197 endocardial cushion development IEA GO:0006468 protein phosphorylation IEA GO:0007162 negative regulation of cell adhesion IDA GO:0007165 signal transduction IDA GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ISS GO:0007409 axonogenesis IEA GO:0007422 peripheral nervous system development IEA GO:0007422 peripheral nervous system development ISS GO:0007507 heart development ISS GO:0007519 skeletal muscle tissue development IEA GO:0007623 circadian rhythm IEA GO:0009611 response to wounding IEA GO:0009968 negative regulation of signal transduction IDA GO:0014037 Schwann cell differentiation ISS GO:0014065 phosphatidylinositol 3-kinase cascade IDA GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade TAS GO:0021545 cranial nerve development ISS GO:0032869 cellular response to insulin stimulus IEA GO:0042060 wound healing NAS GO:0042127 regulation of cell proliferation IDA GO:0042476 odontogenesis IEA GO:0042493 response to drug IEA GO:0043524 negative regulation of neuron apoptosis ISS GO:0043586 tongue development IEA GO:0046326 positive regulation of glucose import IEA GO:0051048 negative regulation of secretion IDA GO:0051402 neuron apoptosis IMP GO:0060056 mammary gland involution IEA GO:0061098 positive regulation of protein tyrosine kinase activity IDA cellular_component GO:0005576 extracellular region IEA GO:0005615 extracellular space IDA GO:0005634 nucleus IEA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane TAS GO:0016020 membrane IEA GO:0016323 basolateral plasma membrane IDA GO:0016324 apical plasma membrane IEA GO:0016328 lateral plasma membrane IEA GO:0043235 receptor complex ISS GO:0045211 postsynaptic membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IEA GO:0004713 protein tyrosine kinase activity IDA GO:0004713 protein tyrosine kinase activity IEA GO:0004714 transmembrane receptor protein tyrosine kinase activity IEA GO:0004716 receptor signaling protein tyrosine kinase activity IEA GO:0004872 receptor activity IEA GO:0004888 transmembrane signaling receptor activity ISS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0019838 growth factor binding IPI GO:0019838 growth factor binding ISS GO:0030296 protein tyrosine kinase activator activity IDA GO:0042803 protein homodimerization activity NAS GO:0046982 protein heterodimerization activity IDA GO:0046982 protein heterodimerization activity IPI

Protein-protein interaction details for ERBB3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID GRB2 Affinity Capture-MS physical 16729043 PIK3R2 Affinity Capture-MS physical 16729043 CSK Affinity Capture-MS physical 16729043 SHC1 Affinity Capture-MS physical 16729043 CD82 Affinity Capture-Western physical 14576349 RGS4 Affinity Capture-Western physical 12840049 RGS4 Affinity Capture-Western physical 12840049 ODF2L Two-hybrid physical 16169070 GRB7 Affinity Capture-Western physical 9516479 PA2G4 Affinity Capture-Western physical 11325528 EGF Reconstituted Complex physical 12093292 RNF41 Reconstituted Complex physical 11867753 NRG1 Reconstituted Complex physical 11555649 NRG1 Reconstituted Complex physical 11555649 NRG1 Reconstituted Complex physical 7592681 PIK3R1 Affinity Capture-Western physical 11546794 PA2G4 Reconstituted Complex physical 10682683 PA2G4 Affinity Capture-Western physical 10682683 IL6ST Affinity Capture-Western physical 11821958 PTK6 Affinity Capture-Western physical 11114724 PIK3R1 Affinity Capture-Western physical 10383151 EGFR Affinity Capture-Western physical 10527633 MUC1 Affinity Capture-Western physical 11278868 NRG1 Reconstituted Complex physical 9168115 NRG2 Reconstituted Complex physical 9168115 ERBB2 Affinity Capture-Western physical 19060928 UBC Affinity Capture-Western physical 17210635 RPN1 PCA physical 12840049 EGR1 PCA physical 12840049 ZNF207 PCA physical 12840049 HDAC6 PCA physical 20029029 LRIG1 Affinity Capture-Western physical 15282549 RNF41 Affinity Capture-Western physical 12411582 RNF41 Reconstituted Complex physical 12411582 UBC Affinity Capture-Western physical 12411582 UBC Affinity Capture-Western physical 10369675 MDM2 Affinity Capture-Western physical 21930127 MDM2 Affinity Capture-Western physical 21930127 AKT1 Affinity Capture-Western physical 21930127 RNF41 Co-fractionation physical 21576364 RNF41 Affinity Capture-Western physical 21576364 UBC Affinity Capture-Western physical 21576364