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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FGB (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002576platelet degranulationTAS
GO:0007165signal transductionIEA
GO:0007596blood coagulationTAS
GO:0030168platelet activationIEA
GO:0030168platelet activationTAS
GO:0051258protein polymerizationIEA
GO:0051592response to calcium ionIDA
cellular_component
GO:0005576extracellular regionNAS
GO:0005576extracellular regionTAS
GO:0005577fibrinogen complexIEA
GO:0005615extracellular spaceIDA
GO:0005615extracellular spaceIEA
GO:0005625soluble fractionTAS
GO:0005886plasma membraneTAS
GO:0005938cell cortexIEA
GO:0009897external side of plasma membraneIDA
GO:0031091platelet alpha granuleIDA
GO:0031093platelet alpha granule lumenTAS
molecular_function
GO:0005102receptor bindingIEA
GO:0030674protein binding, bridgingIEA
GO:0043499eukaryotic cell surface bindingIDA
GO:0051087chaperone bindingIPI

Protein-protein interaction details for FGB (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CALRAffinity Capture-MSphysical7592883
FGGCo-crystal Structurephysical12356313
FGACo-crystal Structurephysical12356313
NID1Reconstituted Complexphysical1680863
FBLN1Reconstituted Complexphysical7642629
LPAReconstituted Complexphysical10980194
LPAAffinity Capture-Westernphysical10980194
KHDRBS2Affinity Capture-MSphysical17643375
MIS12Affinity Capture-MSphysical20360068
GRB7Two-hybridphysical21900206
AIMP2Two-hybridphysical21900206
TK1Two-hybridphysical21900206
CDKN1ATwo-hybridphysical21900206
SMN1Two-hybridphysical21900206
PIK3R3Two-hybridphysical21900206
ANXA7Two-hybridphysical21900206