Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PHF8 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000082G1/S transition of mitotic cell cycleIMP
GO:0007049cell cycleIEA
GO:0007420brain developmentISS
GO:0016568chromatin modificationIEA
GO:0033169histone H3-K9 demethylationIDA
GO:0035574histone H4-K20 demethylationIDA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentIMP
GO:0045943positive regulation of transcription from RNA polymerase I promoterIDA
GO:0061188negative regulation of chromatin silencing at rDNAIDA
GO:0070544histone H3-K36 demethylationIDA
GO:0071557histone H3-K27 demethylationIDA
cellular_component
GO:0005634nucleusIC
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005730nucleolusIDA
molecular_function
GO:0003682chromatin bindingIDA
GO:0005506iron ion bindingIDA
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIDA
GO:0008270zinc ion bindingIEA
GO:0016491oxidoreductase activityIEA
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenIEA
GO:0016706oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donorsIDA
GO:0032452histone demethylase activityIDA
GO:0032454histone demethylase activity (H3-K9 specific)IDA
GO:0035064methylated histone residue bindingIDA
GO:0035575histone demethylase activity (H4-K20 specific)IDA
GO:0046872metal ion bindingIEA
GO:0051864histone demethylase activity (H3-K36 specific)IDA
GO:0071558histone demethylase activity (H3-K27 specific)IDA

Protein-protein interaction details for PHF8 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
RPAP1Affinity Capture-MSphysical17643375
HIST1H3AReconstituted Complexphysical20208542
WDR5Affinity Capture-Westernphysical20208542
ASH2LAffinity Capture-Westernphysical20208542
WDR5Co-localizationphysical20208542
HIST1H3ABiochemical Activityphysical20208542
SUMO2Affinity Capture-MSphysical19394292
HCFC1Affinity Capture-Westernphysical20622854
HIST1H3ABiochemical Activityphysical20346720
HIST1H3AReconstituted Complexphysical20346720
ZNF711Affinity Capture-Westernphysical20346720
ZNF711Two-hybridphysical20346720
ZNF711Affinity Capture-Westernphysical20346720
ZNF711Affinity Capture-MSphysical20346720
SUMO1Reconstituted Complexphysical19596686