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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for PHF8 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000082
G1/S transition of mitotic cell cycle
IMP
GO:0007049
cell cycle
IEA
GO:0007420
brain development
ISS
GO:0016568
chromatin modification
IEA
GO:0033169
histone H3-K9 demethylation
IDA
GO:0035574
histone H4-K20 demethylation
IDA
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
GO:0045893
positive regulation of transcription, DNA-dependent
IMP
GO:0045943
positive regulation of transcription from RNA polymerase I promoter
IDA
GO:0061188
negative regulation of chromatin silencing at rDNA
IDA
GO:0070544
histone H3-K36 demethylation
IDA
GO:0071557
histone H3-K27 demethylation
IDA
cellular_component
GO:0005634
nucleus
IC
GO:0005634
nucleus
IDA
GO:0005634
nucleus
IEA
GO:0005730
nucleolus
IDA
molecular_function
GO:0003682
chromatin binding
IDA
GO:0005506
iron ion binding
IDA
GO:0005515
protein binding
IPI
GO:0008270
zinc ion binding
IDA
GO:0008270
zinc ion binding
IEA
GO:0016491
oxidoreductase activity
IEA
GO:0016702
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
IEA
GO:0016706
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
IDA
GO:0032452
histone demethylase activity
IDA
GO:0032454
histone demethylase activity (H3-K9 specific)
IDA
GO:0035064
methylated histone residue binding
IDA
GO:0035575
histone demethylase activity (H4-K20 specific)
IDA
GO:0046872
metal ion binding
IEA
GO:0051864
histone demethylase activity (H3-K36 specific)
IDA
GO:0071558
histone demethylase activity (H3-K27 specific)
IDA
Protein-protein interaction details for PHF8 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
RPAP1
Affinity Capture-MS
physical
17643375
HIST1H3A
Reconstituted Complex
physical
20208542
WDR5
Affinity Capture-Western
physical
20208542
ASH2L
Affinity Capture-Western
physical
20208542
WDR5
Co-localization
physical
20208542
HIST1H3A
Biochemical Activity
physical
20208542
SUMO2
Affinity Capture-MS
physical
19394292
HCFC1
Affinity Capture-Western
physical
20622854
HIST1H3A
Biochemical Activity
physical
20346720
HIST1H3A
Reconstituted Complex
physical
20346720
ZNF711
Affinity Capture-Western
physical
20346720
ZNF711
Two-hybrid
physical
20346720
ZNF711
Affinity Capture-Western
physical
20346720
ZNF711
Affinity Capture-MS
physical
20346720
SUMO1
Reconstituted Complex
physical
19596686