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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FLNA (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002576 platelet degranulation TAS GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway IMP GO:0007596 blood coagulation TAS GO:0030168 platelet activation TAS GO:0031532 actin cytoskeleton reorganization IDA GO:0034329 cell junction assembly TAS GO:0034394 protein localization at cell surface IDA GO:0042177 negative regulation of protein catabolic process IMP GO:0042993 positive regulation of transcription factor import into nucleus IMP GO:0043113 receptor clustering IDA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IMP GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity IDA GO:0045022 early endosome to late endosome transport IEA GO:0045184 establishment of protein localization IDA GO:0050821 protein stabilization IMP GO:0051220 cytoplasmic sequestering of protein IMP GO:0051764 actin crosslink formation IDA cellular_component GO:0005576 extracellular region TAS GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IMP GO:0005802 trans-Golgi network IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0005938 cell cortex IEA GO:0015629 actin cytoskeleton IC GO:0015629 actin cytoskeleton IDA molecular_function GO:0001948 glycoprotein binding IDA GO:0003779 actin binding IEA GO:0004871 signal transducer activity IMP GO:0005080 protein kinase C binding IEA GO:0005515 protein binding IPI GO:0008134 transcription factor binding IPI GO:0017048 Rho GTPase binding IDA GO:0031267 small GTPase binding IDA GO:0034988 Fc-gamma receptor I complex binding IDA GO:0034989 GTP-Ral binding IDA GO:0042803 protein homodimerization activity IDA GO:0048365 Rac GTPase binding IDA GO:0051015 actin filament binding IDA

Protein-protein interaction details for FLNA (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID DRD3 Two-hybrid physical 11911837 ITGB1 Two-hybrid physical 11807098 VHL Two-hybrid physical 8674032 VHL Two-hybrid physical 12169691 CMIP Two-hybrid physical 15128042 AR Two-hybrid physical 12682292 TRIO Two-hybrid physical 11146652 CASR Two-hybrid physical 11390380 BRCA2 Reconstituted Complex physical 11602572 BRCA2 Affinity Capture-Western physical 11602572 CMIP Affinity Capture-Western physical 15128042 FBLIM1 Two-hybrid physical 12679033 FBLIM1 Affinity Capture-Western physical 12679033 NPHP1 Two-hybrid physical 12006559 NPHP1 Affinity Capture-Western physical 12006559 FLNB Two-hybrid physical 12393796 FLNB Affinity Capture-Western physical 12393796 ITGB3 Two-hybrid physical 11807098 ITGB6 Two-hybrid physical 11807098 ITGB1 Reconstituted Complex physical 11807098 DCN Reconstituted Complex physical 12106908 DRD2 Affinity Capture-Western physical 12181426 F3 Reconstituted Complex physical 9490735 ITGB7 Reconstituted Complex physical 11781567 ITGB1 Two-hybrid physical 9722563 ITGB1 Reconstituted Complex physical 9722563 ITGB1 Affinity Capture-Western physical 9722563 TRAF2 Affinity Capture-Western physical 10617615 BRCA2 Two-hybrid physical 11602572 RALA Affinity Capture-Western physical 10051605 RALA Reconstituted Complex physical 10051605 CASR Reconstituted Complex physical 11390380 GP1BA Affinity Capture-Western physical 11700320 TRIO Reconstituted Complex physical 11146652 MYOT Affinity Capture-Western physical 11038172 CASR Two-hybrid physical 11390379 CASR Affinity Capture-Western physical 11390379 CASR Affinity Capture-Western physical 11390379 SH2B3 Two-hybrid physical 11163396 SH2B3 Affinity Capture-Western physical 11163396 FILIP1 Affinity Capture-Western physical 12055638 FILIP1 Two-hybrid physical 12055638 OTUD1 Affinity Capture-MS physical 19615732 OTUD5 Affinity Capture-MS physical 19615732 USP45 Affinity Capture-MS physical 19615732 G3BP1 Affinity Capture-MS physical 19615732 DMWD Affinity Capture-MS physical 19615732 CAMKK2 Affinity Capture-MS physical 20562859 MAPK14 Two-hybrid physical 20936779 SRC Two-hybrid physical 20936779 APC Two-hybrid physical 20936779 BANF1 Affinity Capture-MS physical 19759913 UBC Affinity Capture-MS physical 16335966 EIF2C3 Affinity Capture-MS physical 19167051 TJP1 Affinity Capture-MS physical 16944923 HDAC5 Affinity Capture-MS physical 21081666 SUMO1 Reconstituted Complex physical 19596686 SVIL Two-hybrid physical 20309963 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572