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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FLT1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000186 activation of MAPKK activity IEA GO:0001569 patterning of blood vessels IEA GO:0001666 response to hypoxia IEA GO:0002040 sprouting angiogenesis IEA GO:0006468 protein phosphorylation IEA GO:0006940 regulation of smooth muscle contraction IEA GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS GO:0007275 multicellular organismal development IEA GO:0007565 female pregnancy TAS GO:0008284 positive regulation of cell proliferation TAS GO:0016477 cell migration IMP GO:0018108 peptidyl-tyrosine phosphorylation IDA GO:0030154 cell differentiation IEA GO:0030335 positive regulation of cell migration IEA GO:0030522 intracellular receptor mediated signaling pathway IEA GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway IDA GO:0043406 positive regulation of MAP kinase activity IDA GO:0043410 positive regulation of MAPKKK cascade IDA GO:0046777 protein autophosphorylation IDA GO:0048010 vascular endothelial growth factor receptor signaling pathway IDA GO:0048010 vascular endothelial growth factor receptor signaling pathway TAS GO:0048514 blood vessel morphogenesis ISS GO:0048598 embryonic morphogenesis ISS GO:0048661 positive regulation of smooth muscle cell proliferation IEA cellular_component GO:0005576 extracellular region IEA GO:0005615 extracellular space TAS GO:0005634 nucleus IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005794 Golgi apparatus IDA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane IEA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IDA GO:0005887 integral to plasma membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004713 protein tyrosine kinase activity IEA GO:0004714 transmembrane receptor protein tyrosine kinase activity TAS GO:0004872 receptor activity IEA GO:0005021 vascular endothelial growth factor-activated receptor activity IDA GO:0005021 vascular endothelial growth factor-activated receptor activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0019838 growth factor binding IEA GO:0019838 growth factor binding IPI GO:0042802 identical protein binding IEA

Protein-protein interaction details for FLT1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SHC1 Two-hybrid physical 10749680 KDR Biochemical Activity physical 12796773 PGF Reconstituted Complex physical 9452434 VEGFB Affinity Capture-Western physical 9751730 VEGFB Reconstituted Complex physical 9751730 SHC2 Two-hybrid physical 10749680 PLCG1 Reconstituted Complex physical 9398617 PLCG1 Two-hybrid physical 9398617 VEGFB Reconstituted Complex physical 10409677 UBC Affinity Capture-Western physical 19883397