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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for GLI2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000122negative regulation of transcription from RNA polymerase II promoterIMP
GO:0001501skeletal system developmentIEA
GO:0001501skeletal system developmentISS
GO:0001649osteoblast differentiationIDA
GO:0001701in utero embryonic developmentIEA
GO:0001822kidney developmentIEA
GO:0001822kidney developmentISS
GO:0002009morphogenesis of an epitheliumIEA
GO:0002076osteoblast developmentIEA
GO:0002076osteoblast developmentISS
GO:0006351transcription, DNA-dependentIDA
GO:0006355regulation of transcription, DNA-dependentIDA
GO:0006915apoptosisIEA
GO:0007224smoothened signaling pathwayIDA
GO:0007382specification of segmental identity, maxillary segmentIEA
GO:0007389pattern specification processIEA
GO:0007389pattern specification processISS
GO:0007411axon guidanceIEA
GO:0007411axon guidanceISS
GO:0007418ventral midline developmentISS
GO:0007442hindgut morphogenesisIEA
GO:0007442hindgut morphogenesisISS
GO:0007507heart developmentIEA
GO:0007507heart developmentISS
GO:0008283cell proliferationIDA
GO:0008284positive regulation of cell proliferationIEA
GO:0008589regulation of smoothened signaling pathwayIEA
GO:0009913epidermal cell differentiationIDA
GO:0009954proximal/distal pattern formationISS
GO:0021508floor plate formationIEA
GO:0021508floor plate formationISS
GO:0021513spinal cord dorsal/ventral patterningIEA
GO:0021513spinal cord dorsal/ventral patterningISS
GO:0021517ventral spinal cord developmentIEA
GO:0021517ventral spinal cord developmentISS
GO:0021696cerebellar cortex morphogenesisIEA
GO:0021696cerebellar cortex morphogenesisISS
GO:0021775smoothened signaling pathway involved in ventral spinal cord interneuron specificationIEA
GO:0021775smoothened signaling pathway involved in ventral spinal cord interneuron specificationISS
GO:0021776smoothened signaling pathway involved in spinal cord motor neuron cell fate specificationIEA
GO:0021915neural tube developmentIEA
GO:0021938smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferationIEA
GO:0021965spinal cord ventral commissure morphogenesisIEA
GO:0021965spinal cord ventral commissure morphogenesisISS
GO:0021983pituitary gland developmentIEA
GO:0021983pituitary gland developmentISS
GO:0030154cell differentiationIEA
GO:0030324lung developmentIEA
GO:0030324lung developmentISS
GO:0030879mammary gland developmentIEA
GO:0030879mammary gland developmentISS
GO:0030902hindbrain developmentIEA
GO:0030902hindbrain developmentISS
GO:0032331negative regulation of chondrocyte differentiationIEA
GO:0033089positive regulation of T cell differentiation in thymusISS
GO:0035295tube developmentIEA
GO:0035295tube developmentISS
GO:0042475odontogenesis of dentine-containing toothIEA
GO:0042475odontogenesis of dentine-containing toothISS
GO:0042733embryonic digit morphogenesisIEA
GO:0045666positive regulation of neuron differentiationIEA
GO:0045740positive regulation of DNA replicationIDA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0048566embryonic digestive tract developmentIEA
GO:0048566embryonic digestive tract developmentISS
GO:0048589developmental growthIEA
GO:0048589developmental growthISS
GO:0048666neuron developmentIEA
GO:0048666neuron developmentISS
GO:0048754branching morphogenesis of a tubeIEA
GO:0048754branching morphogenesis of a tubeISS
GO:0060032notochord regressionIEA
GO:0060513prostatic bud formationIEA
GO:0060603mammary gland duct morphogenesisIEA
GO:0060831smoothened signaling pathway involved in dorsal/ventral neural tube patterningIEA
GO:0071407cellular response to organic cyclic compoundIEA
GO:0090103cochlea morphogenesisIEA
cellular_component
GO:0005622intracellularIEA
GO:0005624membrane fractionIEA
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005737cytoplasmIEA
GO:0005929ciliumIEA
GO:0031512motile primary ciliumIEA
molecular_function
GO:0003677DNA bindingIEA
GO:0003682chromatin bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIDA
GO:0043565sequence-specific DNA bindingIDA
GO:0044212transcription regulatory region DNA bindingIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for GLI2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CREB1Reconstituted Complexphysical10074179
SUFUReconstituted Complexphysical10564661
ZIC1Affinity Capture-Westernphysical11238441
ZIC2Affinity Capture-Westernphysical11238441
ZIC1Reconstituted Complexphysical11238441
STK36Affinity Capture-Westernphysical10806483
HDAC1Affinity Capture-Westernphysical20081843
SKITwo-hybridphysical12435627
SKIReconstituted Complexphysical12435627